Gene Review:
Hoxb1 - homeobox B1
Mus musculus
Synonyms:
Homeobox protein Hox-2.9, Homeobox protein Hox-B1, Hox-2.9, Hoxb-1
- Analysis of two distinct retinoic acid response elements in the homeobox gene Hoxb1 in transgenic mice. Huang, D., Chen, S.W., Gudas, L.J. Dev. Dyn. (2002)
- Cross-talk between glucocorticoid and retinoic acid signals involving glucocorticoid receptor interaction with the homoeodomain protein Pbx1. Subramaniam, N., Campión, J., Rafter, I., Okret, S. Biochem. J. (2003)
- Segmental expression of Hoxb-1 is controlled by a highly conserved autoregulatory loop dependent upon exd/pbx. Pöpperl, H., Bienz, M., Studer, M., Chan, S.K., Aparicio, S., Brenner, S., Mann, R.S., Krumlauf, R. Cell (1995)
- Altered segmental identity and abnormal migration of motor neurons in mice lacking Hoxb-1. Studer, M., Lumsden, A., Ariza-McNaughton, L., Bradley, A., Krumlauf, R. Nature (1996)
- A conserved retinoic acid response element required for early expression of the homeobox gene Hoxb-1. Marshall, H., Studer, M., Pöpperl, H., Aparicio, S., Kuroiwa, A., Brenner, S., Krumlauf, R. Nature (1994)
- Hoxb1 enhancer and control of rhombomere 4 expression: complex interplay between PREP1-PBX1-HOXB1 binding sites. Ferretti, E., Cambronero, F., Tümpel, S., Longobardi, E., Wiedemann, L.M., Blasi, F., Krumlauf, R. Mol. Cell. Biol. (2005)
- Neuronal defects in the hindbrain of Hoxa1, Hoxb1 and Hoxb2 mutants reflect regulatory interactions among these Hox genes. Gavalas, A., Ruhrberg, C., Livet, J., Henderson, C.E., Krumlauf, R. Development (2003)
- Shifting boundaries of retinoic acid activity control hindbrain segmental gene expression. Sirbu, I.O., Gresh, L., Barra, J., Duester, G. Development (2005)
- Hox cluster polarity in early transcriptional availability: a high order regulatory level of clustered Hox genes in the mouse. Roelen, B.A., de Graaff, W., Forlani, S., Deschamps, J. Mech. Dev. (2002)
- Loss of retinoic acid receptor gamma function in F9 cells by gene disruption results in aberrant Hoxa-1 expression and differentiation upon retinoic acid treatment. Boylan, J.F., Lohnes, D., Taneja, R., Chambon, P., Gudas, L.J. Proc. Natl. Acad. Sci. U.S.A. (1993)
- Cross-regulation in the mouse HoxB complex: the expression of Hoxb2 in rhombomere 4 is regulated by Hoxb1. Maconochie, M.K., Nonchev, S., Studer, M., Chan, S.K., Pöpperl, H., Sham, M.H., Mann, R.S., Krumlauf, R. Genes Dev. (1997)
- Ectopic Hoxa-1 induces rhombomere transformation in mouse hindbrain. Zhang, M., Kim, H.J., Marshall, H., Gendron-Maguire, M., Lucas, D.A., Baron, A., Gudas, L.J., Gridley, T., Krumlauf, R., Grippo, J.F. Development (1994)
- Hoxa1 and Hoxb1 synergize in patterning the hindbrain, cranial nerves and second pharyngeal arch. Gavalas, A., Studer, M., Lumsden, A., Rijli, F.M., Krumlauf, R., Chambon, P. Development (1998)
- Cyp26 genes a1, b1 and c1 are down-regulated in Tbx1 null mice and inhibition of Cyp26 enzyme function produces a phenocopy of DiGeorge Syndrome in the chick. Roberts, C., Ivins, S., Cook, A.C., Baldini, A., Scambler, P.J. Hum. Mol. Genet. (2006)
- Postimplantation mouse embryos cultured in vitro. Assessment with whole-mount immunostaining and in situ hybridization. Van Maele-Fabry, G., Clotman, F., Gofflot, F., Bosschaert, J., Picard, J.J. Int. J. Dev. Biol. (1997)
- MEIS C termini harbor transcriptional activation domains that respond to cell signaling. Huang, H., Rastegar, M., Bodner, C., Goh, S.L., Rambaldi, I., Featherstone, M. J. Biol. Chem. (2005)
- Hoxb1 controls effectors of sonic hedgehog and Mash1 signaling pathways. Gaufo, G.O., Flodby, P., Capecchi, M.R. Development (2000)
- PIASxbeta acts as an activator of Hoxb1 and is antagonized by Krox20 during hindbrain segmentation. Garcia-Dominguez, M., Gilardi-Hebenstreit, P., Charnay, P. EMBO J. (2006)
- Roles of Hoxa1 and Hoxa2 in patterning the early hindbrain of the mouse. Barrow, J.R., Stadler, H.S., Capecchi, M.R. Development (2000)
- Altered rhombomere-specific gene expression and hyoid bone differentiation in the mouse segmentation mutant, kreisler (kr). Frohman, M.A., Martin, G.R., Cordes, S.P., Halamek, L.P., Barsh, G.S. Development (1993)
- Mice lacking all isoforms of retinoic acid receptor beta develop normally and are susceptible to the teratogenic effects of retinoic acid. Luo, J., Pasceri, P., Conlon, R.A., Rossant, J., Giguère, V. Mech. Dev. (1995)
- Expression of Hoxb genes in the developing mouse foregut and lung. Bogue, C.W., Lou, L.J., Vasavada, H., Wilson, C.M., Jacobs, H.C. Am. J. Respir. Cell Mol. Biol. (1996)
- Hoxb1 functions in both motoneurons and in tissues of the periphery to establish and maintain the proper neuronal circuitry. Arenkiel, B.R., Tvrdik, P., Gaufo, G.O., Capecchi, M.R. Genes Dev. (2004)
- Expression of class I homeobox genes in fetal and adult murine skin. Detmer, K., Lawrence, H.J., Largman, C. J. Invest. Dermatol. (1993)