Gene Review:
Htr1b - 5-hydroxytryptamine (serotonin) receptor 1B
Mus musculus
Synonyms:
5-HT receptor, 5-HT-1B, 5-HT1B, 5-HT1B receptor, 5-hydroxytryptamine receptor 1B, ...
- The effects of a 5-HT1 receptor ligand isapirone (TVX Q 7821) on 5-HT synthesis and the behavioural effects of 5-HT agonists in mice and rats. Goodwin, G.M., De Souza, R.J., Green, A.R. Psychopharmacology (Berl.) (1986)
- Corticosterone responses in 5-HT1B receptor knockout mice to stress or 5-HT1A receptor activation are normal. Bouwknecht, J.A., van der Gugten, J., Hijzen, T.H., Maes, R.A., Hen, R., Olivier, B. Psychopharmacology (Berl.) (2001)
- 5-HT1B receptors modulate the feeding inhibitory effects of enterostatin. Lin, L., York, D.A. Brain Res. (2005)
- Mouse 5HT1B serotonin receptor: cloning, functional expression, and localization in motor control centers. Maroteaux, L., Saudou, F., Amlaiky, N., Boschert, U., Plassat, J.L., Hen, R. Proc. Natl. Acad. Sci. U.S.A. (1992)
- Modulation of airway hyperresponsiveness and eosinophilia by selective histamine and 5-HT receptor antagonists in a mouse model of allergic asthma. De Bie, J.J., Henricks, P.A., Cruikshank, W.W., Hofman, G., Jonker, E.H., Nijkamp, F.P., Van Oosterhout, A.J. Br. J. Pharmacol. (1998)
- Key role of 5-HT1B receptors in the regulation of paradoxical sleep as evidenced in 5-HT1B knock-out mice. Boutrel, B., Franc, B., Hen, R., Hamon, M., Adrien, J. J. Neurosci. (1999)
- 3,4-N-methlenedioxymethamphetamine-induced hypophagia is maintained in 5-HT1B receptor knockout mice, but suppressed by the 5-HT2C receptor antagonist RS102221. Conductier, G., Crosson, C., Hen, R., Bockaert, J., Compan, V. Neuropsychopharmacology (2005)
- Pharmacogenetic evidence for the involvement of 5-hydroxytryptamine (Serotonin)-1B receptors in the mediation of morphine antinociceptive sensitivity. Hain, H.S., Belknap, J.K., Mogil, J.S. J. Pharmacol. Exp. Ther. (1999)
- Elevated alcohol consumption in null mutant mice lacking 5-HT1B serotonin receptors. Crabbe, J.C., Phillips, T.J., Feller, D.J., Hen, R., Wenger, C.D., Lessov, C.N., Schafer, G.L. Nat. Genet. (1996)
- Increased vulnerability to cocaine in mice lacking the serotonin-1B receptor. Rocha, B.A., Scearce-Levie, K., Lucas, J.J., Hiroi, N., Castanon, N., Crabbe, J.C., Nestler, E.J., Hen, R. Nature (1998)
- Enhanced aggressive behavior in mice lacking 5-HT1B receptor. Saudou, F., Amara, D.A., Dierich, A., LeMeur, M., Ramboz, S., Segu, L., Buhot, M.C., Hen, R. Science (1994)
- Contribution of 5-HT2A receptor in nematode infection-induced murine intestinal smooth muscle hypercontractility. Zhao, A., Urban, J.F., Morimoto, M., Elfrey, J.E., Madden, K.B., Finkelman, F.D., Shea-Donohue, T. Gastroenterology (2006)
- Evidence that RU 24969-induced locomotor activity in C57/B1/6 mice is specifically mediated by the 5-HT1B receptor. Cheetham, S.C., Heal, D.J. Br. J. Pharmacol. (1993)
- Blockade of serotonin 5-HT1B and 5-HT2A receptors suppresses the induction of locomotor activity by 5-HT reuptake inhibitors, citalopram and fluvoxamine, in NMRI mice exposed to a novel environment: a comparison to other 5-HT receptor subtypes. Millan, M.J., Veiga, S., Girardon, S., Brocco, M. Psychopharmacology (Berl.) (2003)
- Analysis of the nature of antagonism of the reserpine-induced hypothermia by imipramine. Francès, H. Naunyn Schmiedebergs Arch. Pharmacol. (1987)
- Roxindole, a dopamine autoreceptor agonist with a potential antidepressant activity. II. Effects on the 5-hydroxytryptamine system. Maj, J., Kołodziejczyk, K., Rogóz, Z., Skuza, G. Pharmacopsychiatry (1997)
- Regional changes in density of serotonin transporter in the brain of 5-HT1A and 5-HT1B knockout mice, and of serotonin innervation in the 5-HT1B knockout. Ase, A.R., Reader, T.A., Hen, R., Riad, M., Descarries, L. J. Neurochem. (2001)
- Hyperphagia Alters Expression of Hypothalamic 5-HT2C and 5-HT1B Receptor Genes and Plasma Des-Acyl Ghrelin Levels in Ay Mice. Nonogaki, K., Nozue, K., Oka, Y. Endocrinology (2006)
- Absence of fenfluramine-induced anorexia and reduced c-Fos induction in the hypothalamus and central amygdaloid complex of serotonin 1B receptor knock-out mice. Lucas, J.J., Yamamoto, A., Scearce-Levie, K., Saudou, F., Hen, R. J. Neurosci. (1998)
- Expression mapping of 5-HT1 serotonin receptor subtypes during fetal and early postnatal mouse forebrain development. Bonnin, A., Peng, W., Hewlett, W., Levitt, P. Neuroscience (2006)
- Serotonergic modulation of retinal input to the mouse suprachiasmatic nucleus mediated by 5-HT1B and 5-HT7 receptors. Smith, B.N., Sollars, P.J., Dudek, F.E., Pickard, G.E. J. Biol. Rhythms (2001)
- Serotonin 5-HT1D receptors. Hoyer, D., Schoeffter, P., Waeber, C., Palacios, J.M. Ann. N. Y. Acad. Sci. (1990)
- Reduced hypophagic effects of d-fenfluramine and the 5-HT2C receptor agonist mCPP in 5-HT1B receptor knockout mice. Lee, M.D., Somerville, E.M., Kennett, G.A., Dourish, C.T., Clifton, P.G. Psychopharmacology (Berl.) (2004)
- Novel potent and selective central 5-HT3 receptor ligands provided with different intrinsic efficacy. 1. Mapping the central 5-HT3 receptor binding site by arylpiperazine derivatives. Cappelli, A., Anzini, M., Vomero, S., Mennuni, L., Makovec, F., Doucet, E., Hamon, M., Bruni, G., Romeo, M.R., Menziani, M.C., De Benedetti, P.G., Langer, T. J. Med. Chem. (1998)
- Coupling of serotonin 5-HT1B receptors to activation of mitogen-activated protein kinase (ERK-2) and p70 S6 kinase signaling systems. Pullarkat, S.R., Mysels, D.J., Tan, M., Cowen, D.S. J. Neurochem. (1998)
- A regulatory role in mammalian salivary glands for 5-hydroxytryptamine receptors coupled to increased cyclic AMP production. Turner, J.T., Sullivan, D.M., Rovira, I., Camden, J.M. J. Dent. Res. (1996)
- Modulation of serotonergic receptor signaling and cross-talk by prion protein. Mouillet-Richard, S., Pietri, M., Schneider, B., Vidal, C., Mutel, V., Launay, J.M., Kellermann, O. J. Biol. Chem. (2005)
- The mouse 5HT5 receptor reveals a remarkable heterogeneity within the 5HT1D receptor family. Plassat, J.L., Boschert, U., Amlaiky, N., Hen, R. EMBO J. (1992)
- 5-HT-receptor-induced changes of the intracellular cAMP level monitored by a hyperpolarization-activated cation channel. Heine, M., Ponimaskin, E., Bickmeyer, U., Richter, D.W. Pflugers Arch. (2002)
- An autoradiographic study of serotonergic receptors in a murine genetic model of anxiety-related behaviors. Clement, Y., Kia, K.H., Daval, G., Verge, D. Brain Res. (1996)
- 5-HT1B receptor knockout mice show a compensatory reduction in 5-HT2C receptor function. Clifton, P.G., Lee, M.D., Somerville, E.M., Kennett, G.A., Dourish, C.T. Eur. J. Neurosci. (2003)
- Serotonin receptors and animal models of aggressive behavior. Olivier, B., Mos, J., van Oorschot, R., Hen, R. Pharmacopsychiatry (1995)
- Differential effects of novel ligands for 5-HT receptor subtypes on nonopioid defensive analgesia in male mice. Rodgers, R.J., Shepherd, J.K., Donát, P. Neuroscience and biobehavioral reviews. (1991)
- Serotonin1B receptor stimulation enhances cocaine reinforcement. Parsons, L.H., Weiss, F., Koob, G.F. J. Neurosci. (1998)
- Humanization of mouse 5-hydroxytryptamine1B receptor gene by homologous recombination: in vitro and in vivo characterization. Bonaventure, P., Umans, L., Bakker, M.H., Cras, P., Langlois, X., Luyten, W.H., Megens, A.A., Serneels, L., Van Leuven, F., Leysen, J.E. Mol. Pharmacol. (1999)