Gene Review:
Lifr - leukemia inhibitory factor receptor
Mus musculus
Synonyms:
A230075M04Rik, AW061234, D-factor/LIF receptor, LIF, LIF receptor, ...
- Suppressor of cytokine signaling 3 limits protection of leukemia inhibitory factor receptor signaling against central demyelination. Emery, B., Cate, H.S., Marriott, M., Merson, T., Binder, M.D., Snell, C., Soo, P.Y., Murray, S., Croker, B., Zhang, J.G., Alexander, W.S., Cooper, H., Butzkueven, H., Kilpatrick, T.J. Proc. Natl. Acad. Sci. U.S.A. (2006)
- Cardiotrophin-1 activates a distinct form of cardiac muscle cell hypertrophy. Assembly of sarcomeric units in series VIA gp130/leukemia inhibitory factor receptor-dependent pathways. Wollert, K.C., Taga, T., Saito, M., Narazaki, M., Kishimoto, T., Glembotski, C.C., Vernallis, A.B., Heath, J.K., Pennica, D., Wood, W.I., Chien, K.R. J. Biol. Chem. (1996)
- The leukemia inhibitory factor receptor gene is not involved in the etiology of pituitary dwarfism in German shepherd dogs. Hanson, J.M., Mol, J.A., Leegwater, P.A., Kooistra, H.S., Meij, B.P. Res. Vet. Sci. (2006)
- LIF receptor signaling limits immune-mediated demyelination by enhancing oligodendrocyte survival. Butzkueven, H., Zhang, J.G., Soilu-Hanninen, M., Hochrein, H., Chionh, F., Shipham, K.A., Emery, B., Turnley, A.M., Petratos, S., Ernst, M., Bartlett, P.F., Kilpatrick, T.J. Nat. Med. (2002)
- Essential function of LIF receptor in motor neurons. Li, M., Sendtner, M., Smith, A. Nature (1995)
- Expression of leukemia inhibitory factor receptor and gp130 in mouse uterus during early pregnancy. Ni, H., Ding, N.Z., Harper, M.J., Yang, Z.M. Mol. Reprod. Dev. (2002)
- The ciliary neurotrophic factor/leukemia inhibitory factor/gp130 receptor complex operates in the maintenance of mammalian forebrain neural stem cells. Shimazaki, T., Shingo, T., Weiss, S. J. Neurosci. (2001)
- Leukemia inhibitory factor and its receptor promote adipocyte differentiation via the mitogen-activated protein kinase cascade. Aubert, J., Dessolin, S., Belmonte, N., Li, M., McKenzie, F.R., Staccini, L., Villageois, P., Barhanin, B., Vernallis, A., Smith, A.G., Ailhaud, G., Dani, C. J. Biol. Chem. (1999)
- Leukemia inhibitory factor, leukemia inhibitory factor receptor, and glycoprotein 130 in rhesus monkey uterus during menstrual cycle and early pregnancy. Yue, Z.P., Yang, Z.M., Wei, P., Li, S.J., Wang, H.B., Tan, J.H., Harper, M.J. Biol. Reprod. (2000)
- Leukemia inhibitory factor signaling is implicated in embrionic development of the HPA axis. Ware, C.B., Kariagina, A., Zonis, S., Alon, D., Chesnokova, V. FEBS Lett. (2005)
- SOCS3: an essential regulator of LIF receptor signaling in trophoblast giant cell differentiation. Takahashi, Y., Carpino, N., Cross, J.C., Torres, M., Parganas, E., Ihle, J.N. EMBO J. (2003)
- Cytoplasmic domains of the leukemia inhibitory factor receptor required for STAT3 activation, differentiation, and growth arrest of myeloid leukemic cells. Tomida, M., Heike, T., Yokota, T. Blood (1999)
- Evidence for heterodimeric association of leukemia inhibitory factor (LIF) receptor and gp130 in the mouse uterus for LIF signaling during blastocyst implantation. Song, H., Lim, H. Reproduction (2006)
- Role of suppressors of cytokine signaling (Socs) in leukemia inhibitory factor (LIF) -dependent embryonic stem cell survival. Duval, D., Reinhardt, B., Kedinger, C., Boeuf, H. FASEB J. (2000)
- Late gestation modulation of fetal glucocorticoid effects requires the receptor for leukemia inhibitory factor: an observational study. Ware, C.B., Nelson, A.M., Liggitt, D. Reprod. Biol. Endocrinol. (2003)
- A secreted and LIF-mediated stromal cell-derived activity that promotes ex vivo expansion of human hematopoietic stem cells. Shih, C.C., Hu, M.C., Hu, J., Weng, Y., Yazaki, P.J., Medeiros, J., Forman, S.J. Blood (2000)
- Targeted disruption of the low-affinity leukemia inhibitory factor receptor gene causes placental, skeletal, neural and metabolic defects and results in perinatal death. Ware, C.B., Horowitz, M.C., Renshaw, B.R., Hunt, J.S., Liggitt, D., Koblar, S.A., Gliniak, B.C., McKenna, H.J., Papayannopoulou, T., Thoma, B. Development (1995)
- Activation of extracellular signal-regulated kinases and CREB/ATF-1 mediate the expression of CCAAT/enhancer binding proteins beta and -delta in preadipocytes. Belmonte, N., Phillips, B.W., Massiera, F., Villageois, P., Wdziekonski, B., Saint-Marc, P., Nichols, J., Aubert, J., Saeki, K., Yuo, A., Narumiya, S., Ailhaud, G., Dani, C. Mol. Endocrinol. (2001)
- Ciliary neurotrophic factor may activate mature astrocytes via binding with the leukemia inhibitory factor receptor. Monville, C., Coulpier, M., Conti, L., De-Fraja, C., Dreyfus, P., Fages, C., Riche, D., Tardy, M., Cattaneo, E., Peschanski, M. Mol. Cell. Neurosci. (2001)
- Loss of leukemia inhibitory factor receptor beta or cardiotrophin-1 causes similar deficits in preganglionic sympathetic neurons and adrenal medulla. Oberle, S., Schober, A., Meyer, V., Holtmann, B., Henderson, C., Sendtner, M., Unsicker, K. J. Neurosci. (2006)
- LIF receptor signaling modulates neural stem cell renewal. Pitman, M., Emery, B., Binder, M., Wang, S., Butzkueven, H., Kilpatrick, T.J. Mol. Cell. Neurosci. (2004)
- mRNA expression of leukaemia inhibitory factor (LIF) and its receptor subunits glycoprotein 130 and LIF-receptor-beta in bovine embryos derived in vitro or in vivo. Eckert, J., Niemann, H. Mol. Hum. Reprod. (1998)
- The signaling pathway of cardiotrophin-1 is not activated in hypertrophied ventricles of carnitine-deficient juvenile visceral steatosis (JVS) mice. Yoshida, G., Horiuchi, M., Kobayashi, K., Jalil, M.D., Iijima, M., Hagihara, S., Nagao, N., Saheki, T. In Vivo (2000)
- Expression of interleukin-6 receptor, leukemia inhibitory factor receptor and glycoprotein 130 in the murine cerebellum and neuropathological effect of leukemia inhibitory factor on cerebellar Purkinje cells. Morikawa, Y., Tohya, K., Tamura, S., Ichihara, M., Miyajima, A., Senba, E. Neuroscience (2000)