Gene Review:
Ltb - lymphotoxin B
Mus musculus
Synonyms:
AI662801, LT-beta, LTbeta, Lymphotoxin-beta, TNF-C, ...
Tumanov,
Kuprash,
Lagarkova,
Grivennikov,
Abe,
Shakhov,
Drutskaya,
Stewart,
Chervonsky,
Nedospasov,
Mackay,
Majeau,
Lawton,
Hochman,
Browning,
Ehlers,
Hölscher,
Scheu,
Tertilt,
Hehlgans,
Suwinski,
Endres,
Pfeffer,
Tumanov,
Grivennikov,
Shakhov,
Rybtsov,
Koroleva,
Takeda,
Nedospasov,
Kuprash,
Manuelidis,
Zaitsev,
Koni,
Lu,
Flavell,
Fritch,
Mabbott,
Young,
McConnell,
Bruce,
Debard,
Sierro,
Browning,
Kraehenbuhl,
- The role of lipopolysaccharide, pro-inflammatory cytokines and bacterial superantigens in the transcriptional regulation of lymphotoxin alpha and beta in mouse splenocytes. Zinetti, M., Agyekum, S., Evans, T., Polak, J., Cohen, J. Cytokine (1998)
- Secreted lymphotoxin-alpha is essential for the control of an intracellular bacterial infection. Roach, D.R., Briscoe, H., Saunders, B., France, M.P., Riminton, S., Britton, W.J. J. Exp. Med. (2001)
- Abnormal development of secondary lymphoid tissues in lymphotoxin beta-deficient mice. Alimzhanov, M.B., Kuprash, D.V., Kosco-Vilbois, M.H., Luz, A., Turetskaya, R.L., Tarakhovsky, A., Rajewsky, K., Nedospasov, S.A., Pfeffer, K. Proc. Natl. Acad. Sci. U.S.A. (1997)
- MAdCAM-1 expressing sacral lymph node in the lymphotoxin beta-deficient mouse provides a site for immune generation following vaginal herpes simplex virus-2 infection. Soderberg, K.A., Linehan, M.M., Ruddle, N.H., Iwasaki, A. J. Immunol. (2004)
- Follicular dendritic cells and dissemination of Creutzfeldt-Jakob disease. Manuelidis, L., Zaitsev, I., Koni, P., Lu, Z.Y., Flavell, R.A., Fritch, W. J. Virol. (2000)
- Defective lymphotoxin-beta receptor-induced NF-kappaB transcriptional activity in NIK-deficient mice. Yin, L., Wu, L., Wesche, H., Arthur, C.D., White, J.M., Goeddel, D.V., Schreiber, R.D. Science (2001)
- Distinct role of surface lymphotoxin expressed by B cells in the organization of secondary lymphoid tissues. Tumanov, A., Kuprash, D., Lagarkova, M., Grivennikov, S., Abe, K., Shakhov, A., Drutskaya, L., Stewart, C., Chervonsky, A., Nedospasov, S. Immunity (2002)
- Distinct roles in lymphoid organogenesis for lymphotoxins alpha and beta revealed in lymphotoxin beta-deficient mice. Koni, P.A., Sacca, R., Lawton, P., Browning, J.L., Ruddle, N.H., Flavell, R.A. Immunity (1997)
- On the role of APC-activation for in vitro versus in vivo T cell priming. Storni, T., Bachmann, M.F. Cell. Immunol. (2003)
- Distinct contributions of TNF and LT cytokines to the development of dendritic cells in vitro and their recruitment in vivo. Abe, K., Yarovinsky, F.O., Murakami, T., Shakhov, A.N., Tumanov, A.V., Ito, D., Drutskaya, L.N., Pfeffer, K., Kuprash, D.V., Komschlies, K.L., Nedospasov, S.A. Blood (2003)
- Differential lymphotoxin-beta and interferon gamma signaling during mouse liver regeneration induced by chronic and acute injury. Akhurst, B., Matthews, V., Husk, K., Smyth, M.J., Abraham, L.J., Yeoh, G.C. Hepatology (2005)
- Dissecting the role of lymphotoxin in lymphoid organs by conditional targeting. Tumanov, A.V., Grivennikov, S.I., Shakhov, A.N., Rybtsov, S.A., Koroleva, E.P., Takeda, J., Nedospasov, S.A., Kuprash, D.V. Immunol. Rev. (2003)
- The lymphotoxin beta receptor is critically involved in controlling infections with the intracellular pathogens Mycobacterium tuberculosis and Listeria monocytogenes. Ehlers, S., Hölscher, C., Scheu, S., Tertilt, C., Hehlgans, T., Suwinski, J., Endres, R., Pfeffer, K. J. Immunol. (2003)
- A role for tumor necrosis factor receptor type 1 in gut-associated lymphoid tissue development: genetic evidence of synergism with lymphotoxin beta. Koni, P.A., Flavell, R.A. J. Exp. Med. (1998)
- Mature follicular dendritic cell networks depend on expression of lymphotoxin beta receptor by radioresistant stromal cells and of lymphotoxin beta and tumor necrosis factor by B cells. Endres, R., Alimzhanov, M.B., Plitz, T., Fütterer, A., Kosco-Vilbois, M.H., Nedospasov, S.A., Rajewsky, K., Pfeffer, K. J. Exp. Med. (1999)
- Differential activities of secreted lymphotoxin-alpha3 and membrane lymphotoxin-alpha1beta2 in lymphotoxin-induced inflammation: critical role of TNF receptor 1 signaling. Sacca, R., Cuff, C.A., Lesslauer, W., Ruddle, N.H. J. Immunol. (1998)
- Novel lymphotoxin alpha (LTalpha) knockout mice with unperturbed tumor necrosis factor expression: reassessing LTalpha biological functions. Liepinsh, D.J., Grivennikov, S.I., Klarmann, K.D., Lagarkova, M.A., Drutskaya, M.S., Lockett, S.J., Tessarollo, L., McAuliffe, M., Keller, J.R., Kuprash, D.V., Nedospasov, S.A. Mol. Cell. Biol. (2006)
- Localization of an endogenous ADP-ribose acceptor, p33, in polymorphonuclear cell granules in chicken liver interlobular connective tissue. Osago, H., Mishima, K., Tsuchiya, M., Tanigawa, Y., Umeno, T., Shimoyama, M. Biochem. Biophys. Res. Commun. (1991)
- Lymphotoxin-beta and TNF regulation in T cell subsets: differential effects of PGE2. Ferreri, N.R., Millet, I., Askari, B., Magnani, P., Ruddle, N.H. Cytokine (1997)
- Follicular dendritic cell dedifferentiation by treatment with an inhibitor of the lymphotoxin pathway dramatically reduces scrapie susceptibility. Mabbott, N.A., Young, J., McConnell, I., Bruce, M.E. J. Virol. (2003)
- Lymphotoxin but not tumor necrosis factor functions to maintain splenic architecture and humoral responsiveness in adult mice. Mackay, F., Majeau, G.R., Lawton, P., Hochman, P.S., Browning, J.L. Eur. J. Immunol. (1997)
- Lymphotoxin plays a crucial role in the development and function of nasal-associated lymphoid tissue through regulation of chemokines and peripheral node addressin. Ying, X., Chan, K., Shenoy, P., Hill, M., Ruddle, N.H. Am. J. Pathol. (2005)
- Differential regulation of lymphotoxin (LT), lymphotoxin-beta (LT-beta), and TNF-alpha in murine T cell clones activated through the TCR. Millet, I., Ruddle, N.H. J. Immunol. (1994)
- Effect of mature lymphocytes and lymphotoxin on the development of the follicle-associated epithelium and M cells in mouse Peyer's patches. Debard, N., Sierro, F., Browning, J., Kraehenbuhl, J.P. Gastroenterology (2001)
- Mature T cell reactivity altered by peptide agonist that induces positive selection. Sebzda, E., Kündig, T.M., Thomson, C.T., Aoki, K., Mak, S.Y., Mayer, J.P., Zamborelli, T., Nathenson, S.G., Ohashi, P.S. J. Exp. Med. (1996)
- Cross-presentation of virus-like particles by skin-derived CD8(-) dendritic cells: a dispensable role for TAP. Ruedl, C., Storni, T., Lechner, F., Bächi, T., Bachmann, M.F. Eur. J. Immunol. (2002)