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Gene Review: 

Mical1  -  microtubule associated monoxygenase,...

Mus musculus

Synonyms: MICAL, MICAL-1, Mical, Molecule interacting with CasL protein 1, NEDD9-interacting protein with calponin homology and LIM domains, ...
 
 
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High impact information on Mical1

  • We propose that the H(2)O(2) produced by this reaction may be one of the signaling molecules involved in axon guidance by MICAL [1].
  • High-resolution structure of the catalytic region of MICAL (molecule interacting with CasL), a multidomain flavoenzyme-signaling molecule [2].
  • Here, we report the 1.45-A resolution crystal structure of the FAD-containing MO domain of mouse MICAL-1 (residues 1-489) [2].

References

  1. Structure and activity of the axon guidance protein MICAL. Nadella, M., Bianchet, M.A., Gabelli, S.B., Barrila, J., Amzel, L.M. Proc. Natl. Acad. Sci. U.S.A. (2005) [Pubmed]
  2. High-resolution structure of the catalytic region of MICAL (molecule interacting with CasL), a multidomain flavoenzyme-signaling molecule. Siebold, C., Berrow, N., Walter, T.S., Harlos, K., Owens, R.J., Stuart, D.I., Terman, J.R., Kolodkin, A.L., Pasterkamp, R.J., Jones, E.Y. Proc. Natl. Acad. Sci. U.S.A. (2005) [Pubmed]
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