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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
Gene Review

Mlf1  -  myeloid leukemia factor 1

Mus musculus

Synonyms: HLS7, Hematopoietic lineage switch 7, Hls7, Myelodysplasia-myeloid leukemia factor 1, Myeloid leukemia factor 1
 
 
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High impact information on Mlf1

 

Biological context of Mlf1

  • These data demonstrate that Mlf1 interferes with an Epo-responsive pathway involving p27(Kip1) accumulation, which inhibits cell cycle arrest essential for erythroid terminal differentiation [2].

References

  1. HLS7, a hemopoietic lineage switch gene homologous to the leukemia-inducing gene MLF1. Williams, J.H., Daly, L.N., Ingley, E., Beaumont, J.G., Tilbrook, P.A., Lalonde, J.P., Stillitano, J.P., Klinken, S.P. EMBO J. (1999) [Pubmed]
  2. Myeloid Leukemia Factor 1 inhibits erythropoietin-induced differentiation, cell cycle exit and p27Kip1 accumulation. Winteringham, L.N., Kobelke, S., Williams, J.H., Ingley, E., Klinken, S.P. Oncogene (2004) [Pubmed]
 

Links

 

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