Gene Review:
DIO3 - deiodinase, iodothyronine, type III
Homo sapiens
Synonyms:
5DIII, D3, DIOIII, ITDI3, TXDI3, ...
Galton,
Huang,
Newman-Tancredi,
Cussac,
Brocco,
Rivet,
Chaput,
Touzard,
Pasteau,
Millan,
Newman-Tancredi,
Cussac,
Audinot,
Millan,
Hernandez,
Martinez,
Croteau,
St Germain,
Huang,
Mulcahey,
Crescenzi,
Chung,
Kim,
Barnes,
Kuijt,
Turano,
Harney,
Larsen,
Hernandez,
Napadow,
Kettner,
Ryan,
Kwong,
Audette,
Hui,
Newman-Tancredi,
Cussac,
Audinot,
Pasteau,
Gavaudan,
Millan,
Kuiper,
Klootwijk,
Visser,
- Regulation of Type III Iodothyronine Deiodinase Expression in Human Cell Lines. Kester, M.H., Kuiper, G.G., Versteeg, R., Visser, T.J. Endocrinology (2006)
- A comparative in vitro and in vivo pharmacological characterization of the novel dopamine D3 receptor antagonists (+)-S 14297, nafadotride, GR 103,691 and U 99194. Audinot, V., Newman-Tancredi, A., Gobert, A., Rivet, J.M., Brocco, M., Lejeune, F., Gluck, L., Desposte, I., Bervoets, K., Dekeyne, A., Millan, M.J. J. Pharmacol. Exp. Ther. (1998)
- Human type 3 iodothyronine selenodeiodinase is located in the plasma membrane and undergoes rapid internalization to endosomes. Baqui, M., Botero, D., Gereben, B., Curcio, C., Harney, J.W., Salvatore, D., Sorimachi, K., Larsen, P.R., Bianco, A.C. J. Biol. Chem. (2003)
- Physiology and pathophysiology of type 3 deiodinase in humans. Huang, S.A. Thyroid (2005)
- The roles of the iodothyronine deiodinases in mammalian development. Galton, V.A. Thyroid (2005)
- The role of central dopamine D3 receptors in drug addiction: a review of pharmacological evidence. Heidbreder, C.A., Gardner, E.L., Xi, Z.X., Thanos, P.K., Mugnaini, M., Hagan, J.J., Ashby, C.R. Brain Res. Brain Res. Rev. (2005)
- Association study of dopamine receptor gene polymorphisms with drug-induced hallucinations in patients with idiopathic Parkinson's disease. Makoff, A.J., Graham, J.M., Arranz, M.J., Forsyth, J., Li, T., Aitchison, K.J., Shaikh, S., Grünewald, R.A. Pharmacogenetics (2000)
- Association between the dopamine D3 receptor gene locus (DRD3) and unipolar affective disorder. Dikeos, D.G., Papadimitriou, G.N., Avramopoulos, D., Karadima, G., Daskalopoulou, E.G., Souery, D., Mendlewicz, J., Vassilopoulos, D., Stefanis, C.N. Psychiatr. Genet. (1999)
- Relative expression of D3 dopamine receptor and alternative splice variant D3nf mRNA in high and low responders to novelty. Pritchard, L.M., Logue, A.D., Taylor, B.C., Ahlbrand, R., Welge, J.A., Tang, Y., Sharp, F.R., Richtand, N.M. Brain Res. Bull. (2006)
- Cloning of the gene for a human dopamine D4 receptor with high affinity for the antipsychotic clozapine. Van Tol, H.H., Bunzow, J.R., Guan, H.C., Sunahara, R.K., Seeman, P., Niznik, H.B., Civelli, O. Nature (1991)
- Biochemistry, cellular and molecular biology, and physiological roles of the iodothyronine selenodeiodinases. Bianco, A.C., Salvatore, D., Gereben, B., Berry, M.J., Larsen, P.R. Endocr. Rev. (2002)
- Type 3 lodothyronine deiodinase: cloning, in vitro expression, and functional analysis of the placental selenoenzyme. Salvatore, D., Low, S.C., Berry, M., Maia, A.L., Harney, J.W., Croteau, W., St Germain, D.L., Larsen, P.R. J. Clin. Invest. (1995)
- G protein activation by human dopamine D3 receptors in high-expressing Chinese hamster ovary cells: A guanosine-5'-O-(3-[35S]thio)- triphosphate binding and antibody study. Newman-Tancredi, A., Cussac, D., Audinot, V., Pasteau, V., Gavaudan, S., Millan, M.J. Mol. Pharmacol. (1999)
- Androgens induce prostate cancer cell proliferation through mammalian target of rapamycin activation and post-transcriptional increases in cyclin D proteins. Xu, Y., Chen, S.Y., Ross, K.N., Balk, S.P. Cancer Res. (2006)
- Staphylococcus saprophyticus hemagglutinin binds fibronectin. Gatermann, S., Meyer, H.G. Infect. Immun. (1994)
- Localization of the type 3 iodothyronine deiodinase (DIO3) gene to human chromosome 14q32 and mouse chromosome 12F1. Hernandez, A., Park, J.P., Lyon, G.J., Mohandas, T.K., St Germain, D.L. Genomics (1998)
- Substitution of cysteine for selenocysteine in the catalytic center of type III iodothyronine deiodinase reduces catalytic efficiency and alters substrate preference. Kuiper, G.G., Klootwijk, W., Visser, T.J. Endocrinology (2003)
- Structure and function of the type 3 deiodinase gene. Hernandez, A. Thyroid (2005)
- Complex organization and structure of sense and antisense transcripts expressed from the DIO3 gene imprinted locus. Hernandez, A., Martinez, M.E., Croteau, W., St Germain, D.L. Genomics (2004)
- Dopamine D2 receptor-mediated G-protein activation in rat striatum: functional autoradiography and influence of unilateral 6-hydroxydopamine lesions of the substantia nigra. Newman-Tancredi, A., Cussac, D., Brocco, M., Rivet, J.M., Chaput, C., Touzard, M., Pasteau, V., Millan, M.J. Brain Res. (2001)
- S 16924 ((R)-2-[1-[2-(2,3-dihydro-benzo[1,4] dioxin-5-Yloxy)-ethyl]-pyrrolidin-3yl]-1-(4-fluoro-phenyl)-ethanone), a novel, potential antipsychotic with marked serotonin (5-HT)1A agonist properties: I. Receptorial and neurochemical profile in comparison with clozapine and haloperidol. Millan, M.J., Gobert, A., Newman-Tancredi, A., Audinot, V., Lejeune, F., Rivet, J.M., Cussac, D., Nicolas, J.P., Muller, O., Lavielle, G. J. Pharmacol. Exp. Ther. (1998)
- S 18126 ([2-[4-(2,3-dihydrobenzo[1,4]dioxin-6-yl)piperazin-1-yl methyl]indan-2-yl]), a potent, selective and competitive antagonist at dopamine D4 receptors: an in vitro and in vivo comparison with L 745,870 (3-(4-[4-chlorophenyl]piperazin-1-yl)methyl-1H-pyrrolo[2, 3b]pyridine) and raclopride. Millan, M.J., Newman-Tancredi, A., Brocco, M., Gobert, A., Lejeune, F., Audinot, V., Rivet, J.M., Schreiber, R., Dekeyne, A., Spedding, M., Nicolas, J.P., Peglion, J.L. J. Pharmacol. Exp. Ther. (1998)
- Transforming growth factor-beta promotes inactivation of extracellular thyroid hormones via transcriptional stimulation of type 3 iodothyronine deiodinase. Huang, S.A., Mulcahey, M.A., Crescenzi, A., Chung, M., Kim, B.W., Barnes, C., Kuijt, W., Turano, H., Harney, J., Larsen, P.R. Mol. Endocrinol. (2005)
- IL-2-dependent induction of G1 cyclins in primary T cells is not blocked by rapamycin or cyclosporin A. Turner, J.M. Int. Immunol. (1993)
- Actions of roxindole at recombinant human dopamine D2, D3 and D4 and serotonin 5-HT1A, 5-HT1B and 5-HT1D receptors. Newman-Tancredi, A., Cussac, D., Audinot, V., Millan, M.J. Naunyn Schmiedebergs Arch. Pharmacol. (1999)
- Somatosensory cortical plasticity in carpal tunnel syndrome--a cross-sectional fMRI evaluation. Napadow, V., Kettner, N., Ryan, A., Kwong, K.K., Audette, J., Hui, K.K. Neuroimage (2006)
- D2-like dopamine receptors are not detectable on human peripheral blood lymphocytes. Vile, J.M., Strange, P.G. Biol. Psychiatry (1996)
- Ontogeny of iodothyronine deiodinases in human liver. Richard, K., Hume, R., Kaptein, E., Sanders, J.P., van Toor, H., De Herder, W.W., den Hollander, J.C., Krenning, E.P., Visser, T.J. J. Clin. Endocrinol. Metab. (1998)
- Reduced activation and increased inactivation of thyroid hormone in tissues of critically ill patients. Peeters, R.P., Wouters, P.J., Kaptein, E., van Toor, H., Visser, T.J., Van den Berghe, G. J. Clin. Endocrinol. Metab. (2003)