The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

Links

 

Gene Review

gpd-3  -  Protein GPD-3

Caenorhabditis elegans

 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

Disease relevance of gpd-3

  • We found that not only is the daf-2(e1370)-enhanced anoxia phenotype dependent upon gpd-2 and gpd-3, but also the motility of animals exposed to brief periods of anoxia is prematurely arrested in gpd-2/3(RNAi) and daf-2(e1370);gpd-2/3(RNAi) animals [1].
 

High impact information on gpd-3

  • Previous studies have indicated a relationship between these two events in the processing of a heat shock-induced gpd-2-gpd-3 polycistronic pre-mRNA [2].
  • The G + T-rich and T-rich regions essential for vertebrate beta-globin polyadenylation were also observed for gpd-3 [3].
 

Biological context of gpd-3

 

Other interactions of gpd-3

  • These data suggest that gpd-2 and gpd-3 may serve a protective role in tissue exposed to oxygen deprivation [1].

References

  1. Glyceraldehyde-3-Phosphate Dehydrogenase Mediates Anoxia Response and Survival in Caenorhabditis elegans. Mendenhall, A.R., Larue, B., Padilla, P.A. Genetics (2006) [Pubmed]
  2. Intercistronic region required for polycistronic pre-mRNA processing in Caenorhabditis elegans. Huang, T., Kuersten, S., Deshpande, A.M., Spieth, J., MacMorris, M., Blumenthal, T. Mol. Cell. Biol. (2001) [Pubmed]
  3. Genomic organization of the glyceraldehyde-3-phosphate dehydrogenase gene family of Caenorhabditis elegans. Huang, X.Y., Barrios, L.A., Vonkhorporn, P., Honda, S., Albertson, D.G., Hecht, R.M. J. Mol. Biol. (1989) [Pubmed]
  4. Conservation of gene organization and trans-splicing in the glyceraldehyde-3-phosphate dehydrogenase-encoding genes of Caenorhabditis briggsae. Lee, Y.H., Huang, X.Y., Hirsh, D., Fox, G.E., Hecht, R.M. Gene (1992) [Pubmed]
 
WikiGenes - Universities