Gene Review:
Pdyn - prodynorphin
Mus musculus
Synonyms:
Beta-neoendorphin-dynorphin, Dyn, Preprodynorphin, Proenkephalin-B
- Morphine-induced changes in the activity of proopiomelanocortin and prodynorphin systems in zymosan-induced peritonitis in mice. Chadzinska, M., Starowicz, K., Scislowska-Czarnecka, A., Bilecki, W., Pierzchala-Koziec, K., Przewlocki, R., Przewlocka, B., Plytycz, B. Immunol. Lett. (2005)
- A model of L-DOPA-induced dyskinesia in 6-hydroxydopamine lesioned mice: relation to motor and cellular parameters of nigrostriatal function. Lundblad, M., Picconi, B., Lindgren, H., Cenci, M.A. Neurobiol. Dis. (2004)
- Mouse insulinoma beta TC3 cells express prodynorphin messenger ribonucleic acid and derived peptides: a unique cellular model for the study of prodynorphin biosynthesis and processing. Vieau, D., Seidah, N.G., Day, R. Endocrinology (1995)
- Mouse strains that lack spinal dynorphin upregulation after peripheral nerve injury do not develop neuropathic pain. Gardell, L.R., Ibrahim, M., Wang, R., Wang, Z., Ossipov, M.H., Malan, T.P., Porreca, F., Lai, J. Neuroscience (2004)
- Big dynorphin, a prodynorphin-derived peptide produces NMDA receptor-mediated effects on memory, anxiolytic-like and locomotor behavior in mice. Kuzmin, A., Madjid, N., Terenius, L., Ogren, S.O., Bakalkin, G. Neuropsychopharmacology (2006)
- Alpha 7-type nicotinic acetylcholine receptor and prodynorphin mRNA expression after administration of (-)-nicotine and U-50,488H in beta-amyloid peptide (25-35)-treated mice. Hiramatsu, M., Watanabe, M., Baba, S., Kojima, R., Nabeshima, T. Ann. N. Y. Acad. Sci. (2004)
- DREAM is a critical transcriptional repressor for pain modulation. Cheng, H.Y., Pitcher, G.M., Laviolette, S.R., Whishaw, I.Q., Tong, K.I., Kockeritz, L.K., Wada, T., Joza, N.A., Crackower, M., Goncalves, J., Sarosi, I., Woodgett, J.R., Oliveira-dos-Santos, A.J., Ikura, M., van der Kooy, D., Salter, M.W., Penninger, J.M. Cell (2002)
- Gene expression profiling of facilitated L-LTP in VP16-CREB mice reveals that BDNF is critical for the maintenance of LTP and its synaptic capture. Barco, A., Patterson, S., Alarcon, J.M., Gromova, P., Mata-Roig, M., Morozov, A., Kandel, E.R. Neuron (2005)
- Opioid peptide gene expression primes cardiogenesis in embryonal pluripotent stem cells. Ventura, C., Maioli, M. Circ. Res. (2000)
- Mg2+ and Ca2+ differentially regulate DNA binding and dimerization of DREAM. Osawa, M., Dace, A., Tong, K.I., Valiveti, A., Ikura, M., Ames, J.B. J. Biol. Chem. (2005)
- Augmented motor activity and reduced striatal preprodynorphin mRNA induction in response to acute amphetamine administration in metabotropic glutamate receptor 1 knockout mice. Mao, L., Conquet, F., Wang, J.Q. Neuroscience (2001)
- Effects of acute "binge" cocaine on preprodynorphin, preproenkephalin, proopiomelanocortin, and corticotropin-releasing hormone receptor mRNA levels in the striatum and hypothalamic-pituitary-adrenal axis of mu-opioid receptor knockout mice. Zhou, Y., Spangler, R., Schlussman, S.D., Yuferov, V.P., Sora, I., Ho, A., Uhl, G.R., Kreek, M.J. Synapse (2002)
- Expression and posttranslational processing of preprodynorphin complementary DNA in the mouse anterior pituitary cell line AtT-20. Devi, L., Gupta, P., Douglass, J. Mol. Endocrinol. (1989)
- Glucose stimulation of pancreatic beta-cell lines induces expression and secretion of dynorphin. Josefsen, K., Buschard, K., Sørensen, L.R., Wøllike, M., Ekman, R., Birkenbach, M. Endocrinology (1998)
- Paradoxical effects of prodynorphin gene deletion on basal and cocaine-evoked dopaminergic neurotransmission in the nucleus accumbens. Chefer, V.I., Shippenberg, T.S. Eur. J. Neurosci. (2006)
- Prodynorphin knockout mice demonstrate diminished age-associated impairment in spatial water maze performance. Nguyen, X.V., Masse, J., Kumar, A., Vijitruth, R., Kulik, C., Liu, M., Choi, D.Y., Foster, T.C., Usynin, I., Bakalkin, G., Bing, G. Behav. Brain Res. (2005)
- Expression of opioid receptors and ligands in pregnant mouse uterus and placenta. Zhu, Y., Pintar, J.E. Biol. Reprod. (1998)
- Impaired preprodynorphin, but not preproenkephalin, mRNA induction in the striatum of mGluR1 mutant mice in response to acute administration of the full dopamine D(1) agonist SKF-82958. Mao, L., Conquet, F., Wang, J.Q. Synapse (2002)
- Prodynorphin and vasopressin mRNA levels are differentially affected by chronic ethanol ingestion in the mouse. Gulya, K., Orpana, A.K., Sikela, J.M., Hoffman, P.L. Brain Res. Mol. Brain Res. (1993)
- The expression of proenkephalin and prodynorphin genes and the induction of c-fos gene by dopaminergic drugs are not altered in the straitum of MPTP-treated mice. Ziolkowska, B., Horn, G., Kupsch, A., Höllt, V. Journal of neural transmission. Parkinson's disease and dementia section. (1995)
- Social defeat stress-induced behavioral responses are mediated by the endogenous kappa opioid system. McLaughlin, J.P., Li, S., Valdez, J., Chavkin, T.A., Chavkin, C. Neuropsychopharmacology (2006)
- Regulation of gene expression by chronic morphine and morphine withdrawal in the locus ceruleus and ventral tegmental area. McClung, C.A., Nestler, E.J., Zachariou, V. J. Neurosci. (2005)
- Isolation and characterization of the mouse homolog of the preprodynorphin (Pdyn) gene. Sharifi, N., Ament, M., Brennan, M.B., Hochgeschwender, U. Neuropeptides (1999)
- Tolerance develops in spinal cord, but not in brain with chronic [Dmt1]DALDA treatment. Ben, Y., Smith, A.P., Schiller, P.W., Lee, N.M. Br. J. Pharmacol. (2004)
- Endogenous opioids and oligodendroglial function: possible autocrine/paracrine effects on cell survival and development. Knapp, P.E., Itkis, O.S., Zhang, L., Spruce, B.A., Bakalkin, G., Hauser, K.F. Glia (2001)