Gene Review:
Spi1 - spleen focus forming virus (SFFV) proviral...
Mus musculus
Synonyms:
31 kDa-transforming protein, Dis-1, Dis1, PU.1, SFFV proviral integration 1 protein, ...
- The murine AIDS defective provirus acts as an insertional mutagen in its infected target B cells. Huang, M., Takac, M., Kozak, C.A., Jolicoeur, P. J. Virol. (1995)
- Granulocytic differentiation of normal hematopoietic precursor cells induced by transcription factor PU.1 correlates with negative regulation of the c-myb promoter. Bellon, T., Perrotti, D., Calabretta, B. Blood (1997)
- The role of Ets family transcription factor PU.1 in hematopoietic cell differentiation, proliferation and apoptosis. Oikawa, T., Yamada, T., Kihara-Negishi, F., Yamamoto, H., Kondoh, N., Hitomi, Y., Hashimoto, Y. Cell Death Differ. (1999)
- Transcriptional regulation of the cyclooxygenase-2 gene in macrophages by PU.1. Joo, M., Park, G.Y., Wright, J.G., Blackwell, T.S., Atchison, M.L., Christman, J.W. J. Biol. Chem. (2004)
- Deregulated expression of the PU.1 transcription factor blocks murine erythroleukemia cell terminal differentiation. Rao, G., Rekhtman, N., Cheng, G., Krasikov, T., Skoultchi, A.I. Oncogene (1997)
- Lymphoid cell growth and transformation are suppressed by a key regulatory element of the gene encoding PU.1. Rosenbauer, F., Owens, B.M., Yu, L., Tumang, J.R., Steidl, U., Kutok, J.L., Clayton, L.K., Wagner, K., Scheller, M., Iwasaki, H., Liu, C., Hackanson, B., Akashi, K., Leutz, A., Rothstein, T.L., Plass, C., Tenen, D.G. Nat. Genet. (2006)
- Down-regulation of c-myc and bcl-2 gene expression in PU.1-induced apoptosis in murine erythroleukemia cells. Kihara-Negishi, F., Yamada, T., Kubota, Y., Kondoh, N., Yamamoto, H., Abe, M., Shirai, T., Hashimoto, Y., Oikawa, T. Int. J. Cancer (1998)
- Protein acetylation regulates both PU.1 transactivation and Ig kappa 3' enhancer activity. Bai, Y., Srinivasan, L., Perkins, L., Atchison, M.L. J. Immunol. (2005)
- PU.1 Redirects Adenovirus to Lysosomes in Alveolar Macrophages, Uncoupling Internalization from Infection. Carey, B., Staudt, M.K., Bonaminio, D., van der Loo, J.C., Trapnell, B.C. J. Immunol. (2007)
- Molecular mapping of chromosome 2 deletions in murine radiation-induced AML localizes a putative tumor suppressor gene to a 1.0 cM region homologous to human chromosome segment 11p11-12. Silver, A., Moody, J., Dunford, R., Clark, D., Ganz, S., Bulman, R., Bouffler, S., Finnon, P., Meijne, E., Huiskamp, R., Cox, R. Genes Chromosomes Cancer (1999)
- Constitutive expression of PU.1 in fetal hematopoietic progenitors blocks T cell development at the pro-T cell stage. Anderson, M.K., Weiss, A.H., Hernandez-Hoyos, G., Dionne, C.J., Rothenberg, E.V. Immunity (2002)
- PU.1 regulates both cytokine-dependent proliferation and differentiation of granulocyte/macrophage progenitors. DeKoter, R.P., Walsh, J.C., Singh, H. EMBO J. (1998)
- PU.1 and GATA: components of a mast cell-specific interleukin 4 intronic enhancer. Henkel, G., Brown, M.A. Proc. Natl. Acad. Sci. U.S.A. (1994)
- The development of functional B lymphocytes in conditional PU.1 knock-out mice. Polli, M., Dakic, A., Light, A., Wu, L., Tarlinton, D.M., Nutt, S.L. Blood (2005)
- Interleukin-3 stimulation of mcl-1 gene transcription involves activation of the PU.1 transcription factor through a p38 mitogen-activated protein kinase-dependent pathway. Wang, J.M., Lai, M.Z., Yang-Yen, H.F. Mol. Cell. Biol. (2003)
- Commitment to the monocytic lineage occurs in the absence of the transcription factor PU.1. Henkel, G.W., McKercher, S.R., Leenen, P.J., Maki, R.A. Blood (1999)
- Crystal structure of PU.1/IRF-4/DNA ternary complex. Escalante, C.R., Brass, A.L., Pongubala, J.M., Shatova, E., Shen, L., Singh, H., Aggarwal, A.K. Mol. Cell (2002)
- Inducible binding of PU.1 and interacting proteins to the Toll-like receptor 4 promoter during endotoxemia. Pedchenko, T.V., Park, G.Y., Joo, M., Blackwell, T.S., Christman, J.W. Am. J. Physiol. Lung Cell Mol. Physiol. (2005)
- Prevention of PU.1-induced growth inhibition and apoptosis but not differentiation block in murine erythroleukemia cells by overexpression of CBP. Manabe, N., Yamamoto, H., Yamada, T., Kihara-Negishi, F., Hashimoto, Y., Mochizuki, M., Oikawa, T. Int. J. Oncol. (2003)
- Microphthalmia transcription factor and PU.1 synergistically induce the leukocyte receptor osteoclast-associated receptor gene expression. So, H., Rho, J., Jeong, D., Park, R., Fisher, D.E., Ostrowski, M.C., Choi, Y., Kim, N. J. Biol. Chem. (2003)
- PU.1 is required for myeloid-derived but not lymphoid-derived dendritic cells. Guerriero, A., Langmuir, P.B., Spain, L.M., Scott, E.W. Blood (2000)
- PU.1 regulates expression of the interleukin-7 receptor in lymphoid progenitors. DeKoter, R.P., Lee, H.J., Singh, H. Immunity (2002)
- Physical and functional interactions between the transcription factor PU.1 and the coactivator CBP. Yamamoto, H., Kihara-Negishi, F., Yamada, T., Hashimoto, Y., Oikawa, T. Oncogene (1999)
- Osteopetrosis in mice lacking haematopoietic transcription factor PU.1. Tondravi, M.M., McKercher, S.R., Anderson, K., Erdmann, J.M., Quiroz, M., Maki, R., Teitelbaum, S.L. Nature (1997)
- PU.1 regulates the commitment of adult hematopoietic progenitors and restricts granulopoiesis. Dakic, A., Metcalf, D., Di Rago, L., Mifsud, S., Wu, L., Nutt, S.L. J. Exp. Med. (2005)