Gene Review:
Slc22a1 - solute carrier family 22 (organic cation...
Mus musculus
Synonyms:
Lx1, Oct1, Orct, Orct1, Organic cation transporter 1, ...
- Cell size regulation, a mechanism that controls cellular RNA accumulation: consequences on regulation of the ubiquitous transcription factors Oct1 and NF-Y and the liver-enriched transcription factor DBP. Schmidt, E.E., Schibler, U. J. Cell Biol. (1995)
- The POU transcription factor Oct-1 represses virus-induced interferon A gene expression. Mesplède, T., Island, M.L., Christeff, N., Petek, F., Doly, J., Navarro, S. Mol. Cell. Biol. (2005)
- Deficiency in the organic cation transporters 1 and 2 (Oct1/Oct2 [Slc22a1/Slc22a2]) in mice abolishes renal secretion of organic cations. Jonker, J.W., Wagenaar, E., Van Eijl, S., Schinkel, A.H. Mol. Cell. Biol. (2003)
- Cloning and functional expression of a mouse liver organic cation transporter. Green, R.M., Lo, K., Sterritt, C., Beier, D.R. Hepatology (1999)
- Transcriptional regulation of murine Slc22a1 (Oct1) by peroxisome proliferator agonist receptor-alpha and -gamma. Nie, W., Sweetser, S., Rinella, M., Green, R.M. Am. J. Physiol. Gastrointest. Liver Physiol. (2005)
- The Lx1 gene maps to mouse chromosome 17 and codes for a protein that is homologous to glucose and polyspecific transmembrane transporters. Schweifer, N., Barlow, D.P. Mamm. Genome (1996)
- T to C substitution at -175 or -173 of the gamma-globin promoter affects GATA-1 and Oct-1 binding in vitro differently but can independently reproduce the hereditary persistence of fetal hemoglobin phenotype in transgenic mice. Liu, L.R., Du, Z.W., Zhao, H.L., Liu, X.L., Huang, X.D., Shen, J., Ju, L.M., Fang, F.D., Zhang, J.W. J. Biol. Chem. (2005)
- Functional expression of a high affinity mammalian hepatic choline/organic cation transporter. Sinclair, C.J., Chi, K.D., Subramanian, V., Ward, K.L., Green, R.M. J. Lipid Res. (2000)
- Reduced hepatic uptake and intestinal excretion of organic cations in mice with a targeted disruption of the organic cation transporter 1 (Oct1 [Slc22a1]) gene. Jonker, J.W., Wagenaar, E., Mol, C.A., Buitelaar, M., Koepsell, H., Smit, J.W., Schinkel, A.H. Mol. Cell. Biol. (2001)
- Involvement of organic cation transporter 1 in hepatic and intestinal distribution of metformin. Wang, D.S., Jonker, J.W., Kato, Y., Kusuhara, H., Schinkel, A.H., Sugiyama, Y. J. Pharmacol. Exp. Ther. (2002)
- Functional characterization of mouse cation transporter mOCT2 compared with mOCT1. Kakehi, M., Koyabu, N., Nakamura, T., Uchiumi, T., Kuwano, M., Ohtani, H., Sawada, Y. Biochem. Biophys. Res. Commun. (2002)
- Yin Yang 1, Oct1, and NFAT-4 form repeating, cyclosporin-sensitive regulatory modules within the murine CD21 intronic control region. Zabel, M.D., Wheeler, W., Weis, J.J., Weis, J.H. J. Immunol. (2002)