Gene Review:
Ube3a - ubiquitin protein ligase E3A
Mus musculus
Synonyms:
4732496B02, 5830462N02Rik, A130086L21Rik, E6-AP ubiquitin protein ligase, Hpve6a, ...
- Paternal deletion from Snrpn to Ube3a in the mouse causes hypotonia, growth retardation and partial lethality and provides evidence for a gene contributing to Prader-Willi syndrome. Tsai, T.F., Jiang, Y.H., Bressler, J., Armstrong, D., Beaudet, A.L. Hum. Mol. Genet. (1999)
- Discovery of a novel, paternally expressed ubiquitin-specific processing protease gene through comparative analysis of an imprinted region of mouse chromosome 7 and human chromosome 19q13.4. Kim, J., Noskov, V.N., Lu, X., Bergmann, A., Ren, X., Warth, T., Richardson, P., Kouprina, N., Stubbs, L. Genome Res. (2000)
- The Prader-Willi syndrome imprinting center activates the paternally expressed murine Ube3a antisense transcript but represses paternal Ube3a. Chamberlain, S.J., Brannan, C.I. Genomics (2001)
- Fast cerebellar oscillation associated with ataxia in a mouse model of Angelman syndrome. Cheron, G., Servais, L., Wagstaff, J., Dan, B. Neuroscience (2005)
- Atp10a, the mouse ortholog of the human imprinted ATP10A gene, escapes genomic imprinting. Kayashima, T., Yamasaki, K., Joh, K., Yamada, T., Ohta, T., Yoshiura, K., Matsumoto, N., Nakane, Y., Mukai, T., Niikawa, N., Kishino, T. Genomics (2003)
- Sleep disturbances in Ube3a maternal-deficient mice modeling Angelman syndrome. Colas, D., Wagstaff, J., Fort, P., Salvert, D., Sarda, N. Neurobiol. Dis. (2005)
- Imprinted expression of the murine Angelman syndrome gene, Ube3a, in hippocampal and Purkinje neurons. Albrecht, U., Sutcliffe, J.S., Cattanach, B.M., Beechey, C.V., Armstrong, D., Eichele, G., Beaudet, A.L. Nat. Genet. (1997)
- Mutation of the Angelman ubiquitin ligase in mice causes increased cytoplasmic p53 and deficits of contextual learning and long-term potentiation. Jiang, Y.H., Armstrong, D., Albrecht, U., Atkins, C.M., Noebels, J.L., Eichele, G., Sweatt, J.D., Beaudet, A.L. Neuron (1998)
- Neurons but not glial cells show reciprocal imprinting of sense and antisense transcripts of Ube3a. Yamasaki, K., Joh, K., Ohta, T., Masuzaki, H., Ishimaru, T., Mukai, T., Niikawa, N., Ogawa, M., Wagstaff, J., Kishino, T. Hum. Mol. Genet. (2003)
- Analysis of imprinting in mice with uniparental duplication of proximal chromosomes 7 and 15 by use of a custom oligonucleotide microarray. Buettner, V.L., Longmate, J.A., Barish, M.E., Mann, J.R., Singer-Sam, J. Mamm. Genome (2004)
- A novel ATPase on mouse chromosome 7 is a candidate gene for increased body fat. Dhar, M., Webb, L.S., Smith, L., Hauser, L., Johnson, D., West, D.B. Physiol. Genomics (2000)
- Regulation of the large (approximately 1000 kb) imprinted murine Ube3a antisense transcript by alternative exons upstream of Snurf/Snrpn. Landers, M., Bancescu, D.L., Le Meur, E., Rougeulle, C., Glatt-Deeley, H., Brannan, C., Muscatelli, F., Lalande, M. Nucleic Acids Res. (2004)
- Dynamic developmental regulation of the large non-coding RNA associated with the mouse 7C imprinted chromosomal region. Le Meur, E., Watrin, F., Landers, M., Sturny, R., Lalande, M., Muscatelli, F. Dev. Biol. (2005)
- Physical mapping of the pink-eyed dilution complex in mouse chromosome 7 shows that Atp10c is the only transcript between Gabrb3 and Ube3a. Dhar, M.S., Hauser, L.J., Nicholls, R.D., Johnson, D.K. DNA Seq. (2004)
- Ube3a expression is not altered in Mecp2 mutant mice. Jordan, C., Francke, U. Hum. Mol. Genet. (2006)
- Neurobehavioral and electroencephalographic abnormalities in Ube3a maternal-deficient mice. Miura, K., Kishino, T., Li, E., Webber, H., Dikkes, P., Holmes, G.L., Wagstaff, J. Neurobiol. Dis. (2002)