Gene Review:
Adcy5 - adenylate cyclase 5
Mus musculus
Synonyms:
AC5, ATP pyrophosphate-lyase 5, AW121902, Ac5, Adenylate cyclase type 5, ...
- Adenylyl cyclase type 5 (AC5) is an essential mediator of morphine action. Kim, K.S., Lee, K.W., Lee, K.W., Im, J.Y., Yoo, J.Y., Kim, S.W., Lee, J.K., Nestler, E.J., Han, P.L. Proc. Natl. Acad. Sci. U.S.A. (2006)
- Impaired D2 dopamine receptor function in mice lacking type 5 adenylyl cyclase. Lee, K.W., Hong, J.H., Choi, I.Y., Che, Y., Lee, J.K., Yang, S.D., Song, C.W., Kang, H.S., Lee, J.H., Noh, J.S., Shin, H.S., Han, P.L. J. Neurosci. (2002)
- Disruption of type 5 adenylyl cyclase gene preserves cardiac function against pressure overload. Okumura, S., Takagi, G., Kawabe, J., Yang, G., Lee, M.C., Hong, C., Liu, J., Vatner, D.E., Sadoshima, J., Vatner, S.F., Ishikawa, Y. Proc. Natl. Acad. Sci. U.S.A. (2003)
- Zinc inhibition of cAMP signaling. Klein, C., Sunahara, R.K., Hudson, T.Y., Heyduk, T., Howlett, A.C. J. Biol. Chem. (2002)
- The type 8 adenylyl cyclase is critical for Ca2+ stimulation of cAMP accumulation in mouse parotid acini. Watson, E.L., Jacobson, K.L., Singh, J.C., Idzerda, R., Ott, S.M., DiJulio, D.H., Wong, S.T., Storm, D.R. J. Biol. Chem. (2000)
- The calcium paradoxon of renin release: calcium suppresses renin exocytosis by inhibition of calcium-dependent adenylate cyclases AC5 and AC6. Gr??nberger, C., Obermayer, B., Klar, J., Kurtz, A., Schweda, F. Circ. Res. (2006)
- Adenylyl cyclase activity and gene expression during mesodermal differentiation of the P19 embryonal carcinoma cells. Lipskaia, L., Grépin, C., Defer, N., Hanoune, J. J. Cell. Physiol. (1998)
- Type 5 adenylyl cyclase disruption alters not only sympathetic but also parasympathetic and calcium-mediated cardiac regulation. Okumura, S., Kawabe, J., Yatani, A., Takagi, G., Lee, M.C., Hong, C., Liu, J., Takagi, I., Sadoshima, J., Vatner, D.E., Vatner, S.F., Ishikawa, Y. Circ. Res. (2003)
- Role of the calcium modulated cyclases in the development of the retinal projections. Nicol, X., Bennis, M., Ishikawa, Y., Chan, G.C., Repérant, J., Storm, D.R., Gaspar, P. Eur. J. Neurosci. (2006)
- Nitric oxide inhibitable isoforms of adenylate cyclase mediate epithelial secretory dysfunction following exposure to ionising radiation. Freeman, S.L., MacNaughton, W.K. Gut (2004)
- Inhibition by calcium of mammalian adenylyl cyclases. Guillou, J.L., Nakata, H., Cooper, D.M. J. Biol. Chem. (1999)
- Photoactivatable agonist of the nicotinic acetylcholine receptor: potential probe to characterize the structural transitions of the acetylcholine binding site in different states of the receptor. Chatrenet, B., Kotzba-Hibert, F., Mulle, C., Changeux, J.P., Goeldner, M.P., Hirth, C. Mol. Pharmacol. (1992)
- Nitric oxide inhibition of cAMP synthesis in parotid acini: regulation of type 5/6 adenylyl cyclase. Watson, E.L., Singh, J.C., Jacobson, K.L., Ott, S.M. Cell. Signal. (2001)
- Forskolin-resistant Y1 adrenal cell mutants are deficient in adenylyl cyclase type 4. Al-Hakim, A., Rui, X., Tsao, J., Albert, P.R., Schimmer, B.P. Mol. Cell. Endocrinol. (2004)