Gene Review:
FGF8 - fibroblast growth factor 8 (androgen-induced)
Homo sapiens
Synonyms:
AIGF, Androgen-induced growth factor, FGF-8, Fibroblast growth factor 8, HBGF-8, ...
Leung,
Frisén,
Cheng,
Lundberg,
Sung,
Fu,
Marsh,
Shih,
Beleza-Meireles,
Kamiakito,
Takayashiki,
Nakamura,
Mirjami M. Mattila,
Pirkko L. Härkönen,
Robson,
Hamdy,
Nordenskjöld,
Kim,
Chu,
Tanaka,
Chou,
Cheng,
Bovolenta,
Ko,
Sakurai,
Gnanapragasam,
Lagerstedt,
Lin,
Saito,
Zhou,
Omrani,
Robinson,
- Regulation of FGF8 expression by the androgen receptor in human prostate cancer. Gnanapragasam, V.J., Robson, C.N., Neal, D.E., Leung, H.Y. Oncogene (2002)
- Loss of Sef (similar expression to FGF) expression is associated with high grade and metastatic prostate cancer. Darby, S., Sahadevan, K., Khan, M.M., Robson, C.N., Leung, H.Y., Gnanapragasam, V.J. Oncogene (2006)
- FGFR2, FGF8, FGF10 and BMP7 as candidate genes for hypospadias. Beleza-Meireles, A., Lundberg, F., Lagerstedt, K., Zhou, X., Omrani, D., Frisén, L., Nordenskjöld, A. Eur. J. Hum. Genet. (2007)
- Forskolin cooperating with growth factor on generation of dopaminergic neurons from human fetal mesencephalic neural progenitor cells. Wang, X., Li, X., Wang, K., Zhou, H., Xue, B., Li, L., Wang, X. Neurosci. Lett. (2004)
- Fibroblast growth factor 8 expression in breast carcinoma: associations with androgen receptor and prostate-specific antigen expressions. Tanaka, A., Kamiakito, T., Takayashiki, N., Sakurai, S., Saito, K. Virchows Arch. (2002)
- Role of fibroblast growth factor 8 in growth and progression of hormonal cancer. Mattila, M.M., Härkönen, P.L. Cytokine Growth Factor Rev. (2007)
- FGF signaling controls somite boundary position and regulates segmentation clock control of spatiotemporal Hox gene activation. Dubrulle, J., McGrew, M.J., Pourquié, O. Cell (2001)
- Regionalization of the prosencephalic neural plate. Rubenstein, J.L., Shimamura, K., Martinez, S., Puelles, L. Annu. Rev. Neurosci. (1998)
- Segmentation in vertebrates: clock and gradient finally joined. Aulehla, A., Herrmann, B.G. Genes Dev. (2004)
- Regionalization of the optic tectum: combinations of gene expression that define the tectum. Nakamura, H. Trends Neurosci. (2001)
- The cephalic neural crest exerts a critical effect on forebrain and midbrain development. Creuzet, S.E., Martinez, S., Le Douarin, N.M. Proc. Natl. Acad. Sci. U.S.A. (2006)
- The human FGF-8 gene localizes on chromosome 10q24 and is subjected to induction by androgen in breast cancer cells. Payson, R.A., Wu, J., Liu, Y., Chiu, I.M. Oncogene (1996)
- NF-kappaB activation upregulates fibroblast growth factor 8 expression in prostate cancer cells. Armstrong, K., Robson, C.N., Leung, H.Y. Prostate (2006)
- Ectodermal FGFs induce perinodular inhibition of limb chondrogenesis in vitro and in vivo via FGF receptor 2. Moftah, M.Z., Downie, S.A., Bronstein, N.B., Mezentseva, N., Pu, J., Maher, P.A., Newman, S.A. Dev. Biol. (2002)
- FGF8 isoform b expression in human prostate cancer. Gnanapragasam, V.J., Robinson, M.C., Marsh, C., Robson, C.N., Hamdy, F.C., Leung, H.Y. Br. J. Cancer (2003)
- Correlation between androgen receptor expression and FGF8 mRNA levels in patients with prostate cancer and benign prostatic hypertrophy. Wang, Q., Stamp, G.W., Powell, S., Abel, P., Laniado, M., Mahony, C., Lalani, E.N., Waxman, J. J. Clin. Pathol. (1999)
- Sequential roles for Fgf4, En1 and Fgf8 in specification and regionalisation of the midbrain. Shamim, H., Mahmood, R., Logan, C., Doherty, P., Lumsden, A., Mason, I. Development (1999)
- Molecular cloning and characterization of human FGF8 alternative messenger RNA forms. Ghosh, A.K., Shankar, D.B., Shackleford, G.M., Wu, K., T'Ang, A., Miller, G.J., Zheng, J., Roy-Burman, P. Cell Growth Differ. (1996)
- Conversion of human umbilical cord mesenchymal stem cells in Wharton's jelly to dopaminergic neurons in vitro: potential therapeutic application for Parkinsonism. Fu, Y.S., Cheng, Y.C., Lin, M.Y., Cheng, H., Chu, P.M., Chou, S.C., Shih, Y.H., Ko, M.H., Sung, M.S. Stem Cells (2006)
- Efficient induction of dopaminergic neurons from embryonic stem cells for application to Parkinson's disease. Kim, D.W. Yonsei Med. J. (2004)
- A role for the hypoblast (AVE) in the initiation of neural induction, independent of its ability to position the primitive streak. Albazerchi, A., Stern, C.D. Dev. Biol. (2007)
- Control of retinoic acid synthesis and FGF expression in the nasal pit is required to pattern the craniofacial skeleton. Song, Y., Hui, J.N., Fu, K.K., Richman, J.M. Dev. Biol. (2004)
- Positive and negative regulations by FGF8 contribute to midbrain roof plate developmental plasticity. Alexandre, P., Bachy, I., Marcou, M., Wassef, M. Development (2006)
- FGF8 induces formation of an ectopic isthmic organizer and isthmocerebellar development via a repressive effect on Otx2 expression. Martinez, S., Crossley, P.H., Cobos, I., Rubenstein, J.L., Martin, G.R. Development (1999)
- Coordinate expression of Fgf8, Otx2, Bmp4, and Shh in the rostral prosencephalon during development of the telencephalic and optic vesicles. Crossley, P.H., Martinez, S., Ohkubo, Y., Rubenstein, J.L. Neuroscience (2001)
- Mapping ligand binding domains in chimeric fibroblast growth factor receptor molecules. Multiple regions determine ligand binding specificity. Chellaiah, A., Yuan, W., Chellaiah, M., Ornitz, D.M. J. Biol. Chem. (1999)
- Sef is synexpressed with FGFs during chick embryogenesis and its expression is differentially regulated by FGFs in the developing limb. Harduf, H., Halperin, E., Reshef, R., Ron, D. Dev. Dyn. (2005)
- Morphogen signaling at the vertebrate growth cone: a few cases or a general strategy? Bovolenta, P. J. Neurobiol. (2005)
- Predominant expression of fibroblast growth factor (FGF) 8, FGF4, and FGF receptor 1 in nonseminomatous and highly proliferative components of testicular germ cell tumors. Suzuki, K., Tokue, A., Kamiakito, T., Kuriki, K., Saito, K., Tanaka, A. Virchows Arch. (2001)
- Increased expression of FGF-8 isoforms and FGF receptors in human premalignant prostatic intraepithelial neoplasia lesions and prostate cancer. Valve, E.M., Nevalainen, M.T., Nurmi, M.J., Laato, M.K., Martikainen, P.M., Härkönen, P.L. Lab. Invest. (2001)