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Gene Review: 

Agfg2  -  ArfGAP with FG repeats 2

Mus musculus

Synonyms: A630095P14Rik, Arf-GAP domain and FG repeat-containing protein 2, HIV-1 Rev-binding protein-like protein, Hrbl, RAB-R, ...
 
 
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High impact information on Hrbl

  • Conversely, coating of thymus cells with rabbit anti-brain serum (RABR) inhibited the binding of C16-31 [1].
  • In previous studies it was demonstrated that rabbit anti-mouse thymus sera (RAT) but not rabbit anti-brain serum (RABR), block the activity of cytotoxic T lymphocytes (CTL) [2].
  • Following heat inactivation RAT and RABR were absorbed with mouse liver and kidney and tested for their capacity to inhibit the attachment of sensitized peritoneal exudate T lymphocytes (PEL) to various target cells [2].
  • Rabbit anti-brain serum (RABR) caused a marked increase of the proliferation of lymphocytes both in the presence or absence of various stimuli and had no effect on the CML [3].

References

  1. A new autoreactive monoclonal antibody specific for the Thy-1 antigen. Rabinowitz, R., Hadar, R., Laskov, R., Schlesinger, M. Thymus (1986) [Pubmed]
  2. Cell surface receptors involved in the attachment of murine cytotoxic T lymphocytes to target cells - a study with xenoantisera to T-cell antigens. Rabinowitz, R., Levy, J., Schlesinger, M. Thymus (1983) [Pubmed]
  3. The effect of xenoantisera on T-lymphocyte functions in the absence of complement. Rabinowitz, R., Laskov, R., Schlesinger, M. Adv. Exp. Med. Biol. (1979) [Pubmed]
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