Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

St6gal2 - beta galactoside alpha 2,6...

Mus musculus

Synonyms: Alpha 2,6-ST 2, Beta-galactoside alpha-2,6-sialyltransferase 2, C230064G14Rik, CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 2, Kiaa1877, ...

Krzewinski-Recchi, M.A. et al., Takashima, S. et al.

Krzewinski-Recchi, Julien, Juliant, Teintenier-Lelièvre, Samyn-Petit, Montiel, Mir, Cerutti, Harduin-Lepers, Delannoy,

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High impact information on St6gal2

Enzymatic assays indicate that the best acceptor substrate of ST6Gal II was the free disaccharide Galbeta1-4GlcNAc structure whereas ST6Gal I preferred Galbeta1-4GlcNAc-R disaccharide sequence linked to a protein [1].
A construction in pFlag vector transfected in COS-7 cells gave raise to a soluble active form of ST6Gal II [1].
The sequence of mouse ST6Gal II encoded a protein of 524 amino acids and showed 77.1% amino acid sequence identity with human ST6Gal II [2].
The ST6Gal II gene is located on chromosome 17 and spans over 70 kb of mouse genomic DNA consisting of at least 6 exons [2].

References

Identification and functional expression of a second human beta-galactoside alpha2,6-sialyltransferase, ST6Gal II. Krzewinski-Recchi, M.A., Julien, S., Juliant, S., Teintenier-Lelièvre, M., Samyn-Petit, B., Montiel, M.D., Mir, A.M., Cerutti, M., Harduin-Lepers, A., Delannoy, P. Eur. J. Biochem. (2003) [Pubmed]
Comparison of the enzymatic properties of mouse beta-galactoside alpha2,6-sialyltransferases, ST6Gal I and II. Takashima, S., Tsuji, S., Tsujimoto, M. J. Biochem. (2003) [Pubmed]

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St6gal2 - beta galactoside alpha 2,6...

Mus musculus

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