The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

Links

 

Gene Review

Asns  -  asparagine synthetase (glutamine-hydrolyzing)

Rattus norvegicus

Synonyms: Glutamine-dependent asparagine synthetase
 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

Disease relevance of Asns

 

High impact information on Asns

 

Biological context of Asns

 

Anatomical context of Asns

  • We studied effects of various agents, including follicle-stimulating hormone (FSH), on changes in the level of asparagine synthetase in cultured rat Sertoli cells [8].
  • Assays on the levels of ASNase and asparagine synthetase indicated an induction of the latter activity, mainly in the pancreas when compared with the level observed in spleen or liver [10].
 

Associations of Asns with chemical compounds

 

Other interactions of Asns

 

Analytical, diagnostic and therapeutic context of Asns

References

  1. Properties of asparagine synthetase in asparagine-independent variants of Jensen rat sarcoma cells induced by 5-azacytidine. Sugiyama, R.H., Arfin, S.M., Harris, M. Mol. Cell. Biol. (1983) [Pubmed]
  2. Purification and properties of asparagine synthetase from rat liver. Hongo, S., Matsumoto, T., Sato, T. Biochim. Biophys. Acta (1978) [Pubmed]
  3. Topographical separation of the catalytic sites of asparagine synthetase explored with monoclonal antibodies. Pfeiffer, N.E., Mehlhaff, P.M., Wylie, D.E., Schuster, S.M. J. Biol. Chem. (1987) [Pubmed]
  4. Import and processing of hybrid proteins by mammalian mitochondria in vitro. Nguyen, M., Argan, C., Lusty, C.J., Shore, G.C. J. Biol. Chem. (1986) [Pubmed]
  5. Cloning of rat asparagine synthetase and specificity of the amino acid-dependent control of its mRNA content. Hutson, R.G., Kilberg, M.S. Biochem. J. (1994) [Pubmed]
  6. Transpupillary thermotherapy-induced modification of angiogenesis- and coagulation-related gene expression in the rat posterior fundus. Ito, Y.N., Ito, M., Takita, H., Yoneya, S., Peyman, G.A., Gehlbach, P.L., Mori, K. Mol. Vis. (2006) [Pubmed]
  7. Hypersensitivity of rat glioma sublines with acquired ACNU resistance to L-asparaginase. Saito, Y., Nakada, Y., Hotta, T., Mikami, T., Kurisu, K., Kiya, K., Kawamoto, K., Uozumi, T. J. Neurosurg. (1991) [Pubmed]
  8. Induction of asparagine synthetase by follicle-stimulating hormone in primary cultures of rat Sertoli cells. Hongo, S., Chiyo, T., Sato, T. Arch. Biochem. Biophys. (1994) [Pubmed]
  9. The effects of dietary amino acids on hepatic L-asparagine synthetase. Markin, R.S., Schuster, S.M. Metab. Clin. Exp. (1984) [Pubmed]
  10. Immobilization of L-asparaginase into a biocompatible poly(ethylene glycol)-albumin hydrogel: evaluation of performance in vivo. Jean-François, J., D'Urso, E.M., Fortier, G. Biotechnol. Appl. Biochem. (1997) [Pubmed]
  11. Methotrexate stimulation of asparagine synthetase activity in rat liver. Maul, D.M., Schuster, S.M. Life Sci. (1982) [Pubmed]
  12. Inhibition of rat liver asparagine synthetase by Cibacron Blue F3GA. Hongo, S., Sato, T. Enzyme (1984) [Pubmed]
  13. Purification of rat liver asparagine synthetase by affinity chromatography on reactive blue 2-agarose. Hongo, S., Sato, T. Anal. Biochem. (1981) [Pubmed]
 
WikiGenes - Universities