Gene Review:
QPCT - glutaminyl-peptide cyclotransferase
Homo sapiens
Synonyms:
EC, GCT, Glutaminyl cyclase, Glutaminyl-peptide cyclotransferase, Glutaminyl-tRNA cyclotransferase, ...
- Epigenetic silencing of novel tumor suppressors in malignant melanoma. Muthusamy, V., Duraisamy, S., Bradbury, C.M., Hobbs, C., Curley, D.P., Nelson, B., Bosenberg, M. Cancer Res. (2006)
- Heterologous expression and characterization of human glutaminyl cyclase: evidence for a disulfide bond with importance for catalytic activity. Schilling, S., Hoffmann, T., Rosche, F., Manhart, S., Wasternack, C., Demuth, H.U. Biochemistry (2002)
- Relationship between parental trinucleotide GCT repeat length and severity of myotonic dystrophy in offspring. Redman, J.B., Fenwick, R.G., Fu, Y.H., Pizzuti, A., Caskey, C.T. JAMA (1993)
- Triplet repeat polymorphism in the transmembrane region of the MICA gene: a strong association of six GCT repetitions with Behçet disease. Mizuki, N., Ota, M., Kimura, M., Ohno, S., Ando, H., Katsuyama, Y., Yamazaki, M., Watanabe, K., Goto, K., Nakamura, S., Bahram, S., Inoko, H. Proc. Natl. Acad. Sci. U.S.A. (1997)
- Human cell lines that elaborate colon-stimulating activity for the marrow cells of man and other species. Di Persio, J.F., Brennan, J.K., Lichtman, M.A., Speiser, B.L. Blood (1978)
- Crystal structures of human glutaminyl cyclase, an enzyme responsible for protein N-terminal pyroglutamate formation. Huang, K.F., Liu, Y.L., Cheng, W.J., Ko, T.P., Wang, A.H. Proc. Natl. Acad. Sci. U.S.A. (2005)
- Combination chemotherapy with gemcitabine plus oxaliplatin in patients with intensively pretreated or refractory germ cell cancer: a study of the German Testicular Cancer Study Group. Kollmannsberger, C., Beyer, J., Liersch, R., Schoeffski, P., Metzner, B., Hartmann, J.T., Rick, O., Stengele, K., Hohloch, K., Spott, C., Kanz, L., Bokemeyer, C. J. Clin. Oncol. (2004)
- Negative cooperativity of substrate binding but not enzyme activity in wild-type and mutant forms of CTP:glycerol-3-phosphate cytidylyltransferase. Sanker, S., Campbell, H.A., Kent, C. J. Biol. Chem. (2001)
- Hepatocytic transcription factor expression in human embryonal carcinoma and yolk sac carcinoma cell lines: expression of HNF-3 alpha in models of early endodermal cell differentiation. Roach, S., Schmid, W., Pera, M.F. Exp. Cell Res. (1994)
- Two missense mutations causing tyrosinemia type 1 with presence and absence of immunoreactive fumarylacetoacetase. Rootwelt, H., Chou, J., Gahl, W.A., Berger, R., Coşkun, T., Brodtkorb, E., Kvittingen, E.A. Hum. Genet. (1994)
- Seladin-1/DHCR24 expression in normal ovary, ovarian epithelial and granulosa tumours. Fuller, P.J., Alexiadis, M., Jobling, T., McNeilage, J. Clin. Endocrinol. (Oxf) (2005)
- Association of multiple nucleotide variations in the pituitary glutaminyl cyclase gene (QPCT) with low radial BMD in adult women. Ezura, Y., Kajita, M., Ishida, R., Yoshida, S., Yoshida, H., Suzuki, T., Hosoi, T., Inoue, S., Shiraki, M., Orimo, H., Emi, M. J. Bone Miner. Res. (2004)
- Evidence for essential histidines in human pituitary glutaminyl cyclase. Bateman, R.C., Temple, J.S., Misquitta, S.A., Booth, R.E. Biochemistry (2001)
- Molecular cloning, sequence analysis and expression of human pituitary glutaminyl cyclase. Song, I., Chuang, C.Z., Bateman, R.C. J. Mol. Endocrinol. (1994)
- The fractionation, characterization, and subcellular localization of colony-stimulating activities released by the human monocyte-like cell line, GCT. DiPersio, J.F., Brennan, J.K., Lichtman, M.A., Abboud, C.N., Kirkpatrick, F.H. Blood (1980)
- Biological characterization of a granulomonopoietic enhancing activity derived from cultured human lipid-containing macrophages. Wang, S.Y., Castro-Malaspina, H., Lu, L., Moore, M.A. Blood (1985)
- Monocyte-macrophage-derived acidic isoferritins: normal feedback regulators of granulocyte-macrophage progenitor cells in vitro. Broxmeyer, H.E., Bognacki, J., Ralph, P., Dörner, M.H., Lu, L., Castro-Malaspina, H. Blood (1982)
- Autostimulation of growth by human myelogenous leukemia cells (HL-60). Brennan, J.K., Abboud, C.N., DiPersio, J.F., Barlow, G.H., Lichtman, M.A. Blood (1981)
- Identification of human glutaminyl cyclase as a metalloenzyme. Potent inhibition by imidazole derivatives and heterocyclic chelators. Schilling, S., Niestroj, A.J., Rahfeld, J.U., Hoffmann, T., Wermann, M., Zunkel, K., Wasternack, C., Demuth, H.U. J. Biol. Chem. (2003)
- Microarray evidence of glutaminyl cyclase gene expression in melanoma: implications for tumor antigen specific immunotherapy. Gillis, J.S. Journal of translational medicine [electronic resource]. (2006)
- Detection of three wound-induced proteins in papaya latex. Azarkan, M., Wintjens, R., Looze, Y., Baeyens-Volant, D. Phytochemistry (2004)
- A general strategy for random insertion and substitution mutagenesis: substoichiometric coupling of trinucleotide phosphoramidites. Sondek, J., Shortle, D. Proc. Natl. Acad. Sci. U.S.A. (1992)
- Clinical impact of germ cell tumor cells in apheresis products of patients receiving high-dose chemotherapy. Bokemeyer, C., Gillis, A.J., Pompe, K., Mayer, F., Metzner, B., Schleucher, N., Schleicher, J., Pflugrad-Jauch, G., Oosterhuis, J.W., Kanz, L., Looijenga, L.H. J. Clin. Oncol. (2001)