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High impact information on TUBG2
- We now report the identification of a second expressed human gamma-tubulin gene (TUBG2) and a gamma-tubulin pseudogene (TUBG1P) in addition to the previously identified gamma-tubulin gene (TUBG1) [1].
Biological context of TUBG2
- TUBG1 and TUBG2 are within 20 kb of each other in region q21 of chromosome 17, and TUBG1P is on chromosome 7 [1].
Other interactions of TUBG2
- The proteins encoded by TUBG1 and TUBG2 share 97.3% amino acid identity, and the two genes are coexpressed in a variety of tissues [1].
Analytical, diagnostic and therapeutic context of TUBG2
- While this assumption is not correct, the similarity of the products of TUBG1 and TUBG2 suggests that results of previous immunolocalization and immunoprecipitation studies in human cells and tissues are likely to be valid [1].
References
- The gamma-tubulin gene family in humans. Wise, D.O., Krahe, R., Oakley, B.R. Genomics (2000) [Pubmed]
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