Gene Review:
THBD - thrombomodulin
Bos taurus
- Hypoxia modulates the barrier and coagulant function of cultured bovine endothelium. Increased monolayer permeability and induction of procoagulant properties. Ogawa, S., Gerlach, H., Esposito, C., Pasagian-Macaulay, A., Brett, J., Stern, D. J. Clin. Invest. (1990)
- Conservative mutations in the immunosuppressive region of the bovine leukemia virus transmembrane protein affect fusion but not infectivity in vivo. Gatot, J.S., Callebaut, I., Mornon, J.P., Portetelle, D., Burny, A., Kerkhofs, P., Kettmann, R., Willems, L. J. Biol. Chem. (1998)
- Decrease in endothelial cell-dependent protein C activation induced by thrombomodulin by treatment with cyclosporine. Garcia-Maldonado, M., Kaufman, C.E., Comp, P.C. Transplantation (1991)
- Recombinant Jembrana disease virus proteins as antigens for the detection of antibody to bovine lentiviruses. Burkala, E.J., Narayani, I., Hartaningsih, N., Kertayadnya, G., Berryman, D.I., Wilcox, G.E. J. Virol. Methods (1998)
- Endothelial receptor-mediated binding of glucose-modified albumin is associated with increased monolayer permeability and modulation of cell surface coagulant properties. Esposito, C., Gerlach, H., Brett, J., Stern, D., Vlassara, H. J. Exp. Med. (1989)
- Solution structure of the smallest cofactor-active fragment of thrombomodulin. Wood, M.J., Sampoli Benitez, B.A., Komives, E.A. Nat. Struct. Biol. (2000)
- Characterization of a thrombomodulin cDNA reveals structural similarity to the low density lipoprotein receptor. Jackman, R.W., Beeler, D.L., VanDeWater, L., Rosenberg, R.D. Proc. Natl. Acad. Sci. U.S.A. (1986)
- Bovine leukemia virus gp30 transmembrane (TM) protein is not tyrosine phosphorylated: examining potential interactions with host tyrosine-mediated signaling. Hamilton, V.T., Stone, D.M., Pritchard, S.M., Cantor, G.H. Virus Res. (2002)
- Tumor necrosis factor leads to the internalization and degradation of thrombomodulin from the surface of bovine aortic endothelial cells in culture. Moore, K.L., Esmon, C.T., Esmon, N.L. Blood (1989)
- The active site of the thrombin-thrombomodulin complex. A fluorescence energy transfer measurement of its distance above the membrane surface. Lu, R.L., Esmon, N.L., Esmon, C.T., Johnson, A.E. J. Biol. Chem. (1989)
- The effect of bovine thrombomodulin on the specificity of bovine thrombin. Jakubowski, H.V., Kline, M.D., Owen, W.G. J. Biol. Chem. (1986)
- Thrombomodulin blocks the ability of thrombin to activate platelets. Esmon, N.L., Carroll, R.C., Esmon, C.T. J. Biol. Chem. (1983)
- Regulation of brain capillary endothelial thrombomodulin mRNA expression. Tran, N.D., Wong, V.L., Schreiber, S.S., Bready, J.V., Fisher, M. Stroke (1996)
- Endothelial expression of thrombomodulin is reversibly regulated by fluid shear stress. Malek, A.M., Jackman, R., Rosenberg, R.D., Izumo, S. Circ. Res. (1994)
- Thrombomodulin expression in bovine brain capillaries. Anticoagulant function of the blood-brain barrier, regional differences, and regulatory mechanisms. Wang, L., Tran, N.D., Kittaka, M., Fisher, M.J., Schreiber, S.S., Zlokovic, B.V. Arterioscler. Thromb. Vasc. Biol. (1997)
- cAMP influence on transcription of thrombomodulin is dependent on de novo synthesis of a protein intermediate: evidence for cohesive regulation of myogenic proteins in vascular smooth muscle. Traynor, A.E., Cundiff, D.L., Soff, G.A. J. Lab. Clin. Med. (1995)
- Reconstitution of rabbit thrombomodulin into phospholipid vesicles. Galvin, J.B., Kurosawa, S., Moore, K., Esmon, C.T., Esmon, N.L. J. Biol. Chem. (1987)
- Formation of activated protein C and inactivation of cell-bound thrombin by antithrombin III at the surface of cultured vascular endothelial cells--a comparative study of two anticoagulant mechanisms. Delvos, U., Meusel, P., Preissner, K.T., Müller-Berghaus, G. Thromb. Haemost. (1987)
- Chelerythrine, a selective protein kinase C inhibitor, counteracts pyrogen-induced expression of tissue factor without effect on thrombomodulin down-regulation in endothelial cells. Herbert, J.M., Savi, P., Laplace, M.C., Dumas, A., Dol, F. Thromb. Res. (1993)