Gene Review:
SPARC - secreted protein, acidic, cysteine-rich...
Bos taurus
- Osteonectin mRNA: distribution in normal and transformed cells. Young, M.F., Bolander, M.E., Day, A.A., Ramis, C.I., Robey, P.G., Yamada, Y., Termine, J.D. Nucleic Acids Res. (1986)
- Immunological screening of SPARC/Osteonectin in nonmineralized tissues. Maillard, C., Malaval, L., Delmas, P.D. Bone (1992)
- Renaturation of SPARC expressed in Escherichia coli requires isomerization of disulfide bonds for recovery of biological activity. Bassuk, J.A., Braun, L.P., Motamed, K., Baneyx, F., Sage, E.H. Int. J. Biochem. Cell Biol. (1996)
- SPARC is expressed by ganglion cells and astrocytes in bovine retina. Yan, Q., Sage, E.H., Hendrickson, A.E. J. Histochem. Cytochem. (1998)
- SPARC inhibits endothelial cell adhesion but not proliferation through a tyrosine phosphorylation-dependent pathway. Motamed, K., Sage, E.H. J. Cell. Biochem. (1998)
- Expression of tissue transglutaminase in skeletal tissues correlates with events of terminal differentiation of chondrocytes. Aeschlimann, D., Wetterwald, A., Fleisch, H., Paulsson, M. J. Cell Biol. (1993)
- Focal adhesion integrity is downregulated by the alternatively spliced domain of human tenascin. Murphy-Ullrich, J.E., Lightner, V.A., Aukhil, I., Yan, Y.Z., Erickson, H.P., Höök, M. J. Cell Biol. (1991)
- SPARC, a secreted protein associated with cellular proliferation, inhibits cell spreading in vitro and exhibits Ca+2-dependent binding to the extracellular matrix. Sage, H., Vernon, R.B., Funk, S.E., Everitt, E.A., Angello, J. J. Cell Biol. (1989)
- Secreted protein acidic, rich in cysteine (SPARC), mediates cellular survival of gliomas through AKT activation. Shi, Q., Bao, S., Maxwell, J.A., Reese, E.D., Friedman, H.S., Bigner, D.D., Wang, X.F., Rich, J.N. J. Biol. Chem. (2004)
- Evidence for positive and negative regulatory elements in the 5'-flanking sequence of the mouse sparc (osteonectin) gene. Nomura, S., Hashmi, S., McVey, J.H., Ham, J., Parker, M., Hogan, B.L. J. Biol. Chem. (1989)
- Osteonectin cDNA sequence reveals potential binding regions for calcium and hydroxyapatite and shows homologies with both a basement membrane protein (SPARC) and a serine proteinase inhibitor (ovomucoid). Bolander, M.E., Young, M.F., Fisher, L.W., Yamada, Y., Termine, J.D. Proc. Natl. Acad. Sci. U.S.A. (1988)
- Characterization of porcine osteonectin extracted from foetal calvariae. Domenicucci, C., Goldberg, H.A., Hofmann, T., Isenman, D., Wasi, S., Sodek, J. Biochem. J. (1988)
- SPARC (secreted protein acidic and rich in cysteine) regulates endothelial cell shape and barrier function. Goldblum, S.E., Ding, X., Funk, S.E., Sage, E.H. Proc. Natl. Acad. Sci. U.S.A. (1994)
- The Ca2(+)-binding glycoprotein SPARC modulates cell cycle progression in bovine aortic endothelial cells. Funk, S.E., Sage, E.H. Proc. Natl. Acad. Sci. U.S.A. (1991)
- Cyclic GMP-dependent protein kinase is required for thrombospondin and tenascin mediated focal adhesion disassembly. Murphy-Ullrich, J.E., Pallero, M.A., Boerth, N., Greenwood, J.A., Lincoln, T.M., Cornwell, T.L. J. Cell. Sci. (1996)
- Isolation and characterization of native adult osteonectin. Romberg, R.W., Werness, P.G., Lollar, P., Riggs, B.L., Mann, K.G. J. Biol. Chem. (1985)
- Isolation and characterization of a cell surface albumin-binding protein from vascular endothelial cells. Tiruppathi, C., Finnegan, A., Malik, A.B. Proc. Natl. Acad. Sci. U.S.A. (1996)
- SPARC induces the expression of type 1 plasminogen activator inhibitor in cultured bovine aortic endothelial cells. Hasselaar, P., Loskutoff, D.J., Sawdey, M., Sage, E.H. J. Biol. Chem. (1991)
- Influence of titanium surfaces on attachment of osteoblast-like cells in vitro. Jayaraman, M., Meyer, U., Bühner, M., Joos, U., Wiesmann, H.P. Biomaterials (2004)
- Rat embryo fibroblasts transformed by c-Jun display highly metastatic and angiogenic activities in vivo and deregulate gene expression of both angiogenic and antiangiogenic factors. Kraemer, M., Tournaire, R., Dejong, V., Montreau, N., Briane, D., Derbin, C., Binétruy, B. Cell Growth Differ. (1999)
- Gene expression profiling of peripheral blood mononuclear cells from cattle infected with Mycobacterium paratuberculosis. Coussens, P.M., Colvin, C.J., Wiersma, K., Abouzied, A., Sipkovsky, S. Infect. Immun. (2002)
- Loss of insulin-like growth factor I receptor-dependent expression of p107 and cyclin A in cells that lack the extracellular matrix protein secreted protein acidic and rich in cysteine. Basu, A., Rodeck, U., Prendergast, G.C., Howe, C.C. Cell Growth Differ. (1999)
- Diverse forms of stress result in changes in cellular levels of osteonectin/SPARC without altering mRNA levels in osteoligament cells. Sauk, J.J., Norris, K., Kerr, J.M., Somerman, M.J., Young, M.F. Calcif. Tissue Int. (1991)
- Endotoxin alters the expression of extracellular matrix proteins by cultured endothelial cells. Sawhney, R.S., Bone, R.C. Cell. Mol. Biol. Res. (1993)