Gene Review:
GSN - gelsolin
Homo sapiens
Synonyms:
ADF, AGEL, Actin-depolymerizing factor, Brevin, DKFZp313L0718, ...
- Gelsolin-derived familial amyloidosis caused by asparagine or tyrosine substitution for aspartic acid at residue 187. de la Chapelle, A., Tolvanen, R., Boysen, G., Santavy, J., Bleeker-Wagemakers, L., Maury, C.P., Kere, J. Nat. Genet. (1992)
- Modulation of androgen receptor transactivation by gelsolin: a newly identified androgen receptor coregulator. Nishimura, K., Ting, H.J., Harada, Y., Tokizane, T., Nonomura, N., Kang, H.Y., Chang, H.C., Yeh, S., Miyamoto, H., Shin, M., Aozasa, K., Okuyama, A., Chang, C. Cancer Res. (2003)
- Gelsolin variant (Asn-187) in familial amyloidosis, Finnish type. Ghiso, J., Haltia, M., Prelli, F., Novello, J., Frangione, B. Biochem. J. (1990)
- ADF, a growth-promoting factor derived from adult T cell leukemia and homologous to thioredoxin: involvement in lymphocyte immortalization by HTLV-I and EBV. Yodoi, J., Tursz, T. Adv. Cancer Res. (1991)
- Increased expression of human thioredoxin/adult T cell leukemia-derived factor in Sjögren's syndrome. Saito, I., Shimuta, M., Terauchi, K., Tsubota, K., Yodoi, J., Miyasaka, N. Arthritis Rheum. (1996)
- Two actin binding proteins, actin depolymerizing factor and cofilin, are associated with Hirano bodies. Maciver, S.K., Harrington, C.R. Neuroreport (1995)
- Redox regulation of cellular activation. Nakamura, H., Nakamura, K., Yodoi, J. Annu. Rev. Immunol. (1997)
- Beta-secretase-cleaved amyloid precursor protein accumulates at actin inclusions induced in neurons by stress or amyloid beta: a feedforward mechanism for Alzheimer's disease. Maloney, M.T., Minamide, L.S., Kinley, A.W., Boyle, J.A., Bamburg, J.R. J. Neurosci. (2005)
- Scavenging system efficiency is crucial for cell resistance to ROS-mediated methylglyoxal injury. Amicarelli, F., Colafarina, S., Cattani, F., Cimini, A., Di Ilio, C., Ceru, M.P., Miranda, M. Free Radic. Biol. Med. (2003)
- Human glioblastoma ADF cells express tyrosinase, L-tyrosine hydroxylase and melanosomes and are sensitive to L-tyrosine and phenylthiourea. Bonfigli, A., Zarivi, O., Colafarina, S., Cimini, A.M., Ragnelli, A.M., Aimola, P., Natali, P.G., Cerù, M.P., Amicarelli, F., Miranda, M. J. Cell. Physiol. (2006)
- PPARgamma-dependent effects of conjugated linoleic acid on the human glioblastoma cell line (ADF). Cimini, A., Cristiano, L., Colafarina, S., Benedetti, E., Di Loreto, S., Festuccia, C., Amicarelli, F., Canuto, R.A., Cerù, M.P. Int. J. Cancer (2005)
- Analysis of localization of adult T-cell leukemia-derived factor in the transient ischemic rat retina after treatment with OP-1206 alpha-CD, a prostaglandin E1 analogue. Yamamoto, M., Ohira, A., Honda, O., Sato, N., Furuke, K., Yodoi, J., Honda, Y. J. Histochem. Cytochem. (1997)
- Identification of a highly polymorphic microsatellite VNTR within the argininosuccinate synthetase locus: exclusion of the dystonia gene on 9q32-34 as the cause of dopa-responsive dystonia in a large kindred. Kwiatkowski, D.J., Nygaard, T.G., Schuback, D.E., Perman, S., Trugman, J.M., Bressman, S.B., Burke, R.E., Brin, M.F., Ozelius, L., Breakefield, X.O. Am. J. Hum. Genet. (1991)
- Age-dependent transcription factor (ADF) interacts with prostate-specific antigen (PSA) gene enhancer. Zaidi, G., Supakar, P.C. Mol. Biol. Rep. (2002)
- Phosphorylation of actin-depolymerizing factor/cofilin by LIM-kinase mediates amyloid beta-induced degeneration: a potential mechanism of neuronal dystrophy in Alzheimer's disease. Heredia, L., Helguera, P., de Olmos, S., Kedikian, G., Solá Vigo, F., LaFerla, F., Staufenbiel, M., de Olmos, J., Busciglio, J., Cáceres, A., Lorenzo, A. J. Neurosci. (2006)
- Differential regulation of actin depolymerizing factor and cofilin in response to alterations in the actin monomer pool. Minamide, L.S., Painter, W.B., Schevzov, G., Gunning, P., Bamburg, J.R. J. Biol. Chem. (1997)
- LIM-kinase 2 induces formation of stress fibres, focal adhesions and membrane blebs, dependent on its activation by Rho-associated kinase-catalysed phosphorylation at threonine-505. Amano, T., Tanabe, K., Eto, T., Narumiya, S., Mizuno, K. Biochem. J. (2001)
- Organization and translation of mRNA in sympathetic axons. Lee, S.K., Hollenbeck, P.J. J. Cell. Sci. (2003)
- Adenovirus mediated gelsolin gene therapy for orthotopic human bladder cancer in nude mice. Sazawa, A., Watanabe, T., Tanaka, M., Haga, K., Fujita, H., Harabayashi, T., Shinohara, N., Koyanagi, T., Kuzumaki, N. J. Urol. (2002)
- Antagonistic effects of cofilin, beryllium fluoride complex, and phalloidin on subdomain 2 and nucleotide-binding cleft in f-actin. Muhlrad, A., Ringel, I., Pavlov, D., Peyser, Y.M., Reisler, E. Biophys. J. (2006)
- Voltage-dependent actions of endogenous and exogenous serotonin on identified neurones. Cottrell, G.A. Comp. Biochem. Physiol. C, Comp. Pharmacol. (1982)
- Posttranslational N-myristoylation is required for the anti-apoptotic activity of human tGelsolin, the C-terminal caspase cleavage product of human gelsolin. Sakurai, N., Utsumi, T. J. Biol. Chem. (2006)
- Amyloid protein in familial amyloidosis (Finnish type) is homologous to gelsolin, an actin-binding protein. Haltia, M., Prelli, F., Ghiso, J., Kiuru, S., Somer, H., Palo, J., Frangione, B. Biochem. Biophys. Res. Commun. (1990)
- Prescription for the design and selection of density functional approximations: more constraint satisfaction with fewer fits. Perdew, J.P., Ruzsinszky, A., Tao, J., Staroverov, V.N., Scuseria, G.E., Csonka, G.I. The Journal of chemical physics. (2005)
- Brevin, a serum protein that acts on the barbed end of actin filaments. Wilkins, J.A., Schwartz, J.H., Harris, D.A. Cell Biol. Int. Rep. (1983)
- Remodeling of actin cytoskeleton in lupeol-induced B16 2F2 cell differentiation. Hata, K., Hori, K., Murata, J., Takahashi, S. J. Biochem. (2005)
- Transmission disequilibrium analysis of the GSN gene in a cohort of family trios with schizophrenia. Xi, Z.R., Qin, W., Yang, Y.F., He, G., Gao, S.H., Ren, M.S., Peng, Y.W., Zhang, Z., He, L. Neurosci. Lett. (2004)