Gene Review:
SENP1 - SUMO1/sentrin specific peptidase 1
Homo sapiens
Synonyms:
Sentrin-specific protease 1, Sentrin/SUMO-specific protease SENP1
- Mapping residues of SUMO precursors essential in differential maturation by SUMO-specific protease, SENP1. Xu, Z., Au, S.W. Biochem. J. (2005)
- Role of desumoylation in the development of prostate cancer. Cheng, J., Bawa, T., Lee, P., Gong, L., Yeh, E.T. Neoplasia (2006)
- SUMO-specific protease 1 (SENP1) reverses the hormone-augmented SUMOylation of androgen receptor and modulates gene responses in prostate cancer cells. Kaikkonen, S., Jääskeläinen, T., Karvonen, U., Rytinki, M.M., Makkonen, H., Gioeli, D., Paschal, B.M., Palvimo, J.J. Mol. Endocrinol. (2009)
- Nucleocytoplasmic shuttling modulates activity and ubiquitination-dependent turnover of SUMO-specific protease 2. Itahana, Y., Yeh, E.T., Zhang, Y. Mol. Cell. Biol. (2006)
- Fusion of the SUMO/Sentrin-specific protease 1 gene SENP1 and the embryonic polarity-related mesoderm development gene MESDC2 in a patient with an infantile teratoma and a constitutional t(12;15)(q13;q25). Veltman, I.M., Vreede, L.A., Cheng, J., Looijenga, L.H., Janssen, B., Schoenmakers, E.F., Yeh, E.T., van Kessel, A.G. Hum. Mol. Genet. (2005)
- SENP1 enhances androgen receptor-dependent transcription through desumoylation of histone deacetylase 1. Cheng, J., Wang, D., Wang, Z., Yeh, E.T. Mol. Cell. Biol. (2004)
- Differential regulation of c-Jun-dependent transcription by SUMO-specific proteases. Cheng, J., Perkins, N.D., Yeh, E.T. J. Biol. Chem. (2005)
- Desumoylation of homeodomain-interacting protein kinase 2 (HIPK2) through the cytoplasmic-nuclear shuttling of the SUMO-specific protease SENP1. Kim, Y.H., Sung, K.S., Lee, S.J., Kim, Y.O., Choi, C.Y., Kim, Y. FEBS Lett. (2005)
- The structure of SENP1-SUMO-2 complex suggests a structural basis for discrimination between SUMO paralogues during processing. Shen, L.N., Dong, C., Liu, H., Naismith, J.H., Hay, R.T. Biochem. J. (2006)
- Inhibition of SUMO-independent PML oligomerization by the human cytomegalovirus IE1 protein. Kang, H., Kim, E.T., Lee, H.R., Park, J.J., Go, Y.Y., Choi, C.Y., Ahn, J.H. J. Gen. Virol. (2006)
- Differential regulation of sentrinized proteins by a novel sentrin-specific protease. Gong, L., Millas, S., Maul, G.G., Yeh, E.T. J. Biol. Chem. (2000)
- Herpes simplex virus 1 ICP0 co-localizes with a SUMO-specific protease. Bailey, D., O'Hare, P. J. Gen. Virol. (2002)
- PIASy-mediated repression of the Ets-1 is independent of its sumoylation. Nishida, T., Terashima, M., Fukami, K. Biochem. Biophys. Res. Commun. (2006)
- Crystal structure of the SENP1 mutant C603S-SUMO complex reveals the hydrolytic mechanism of SUMO-specific protease. Xu, Z., Chau, S.F., Lam, K.H., Chan, H.Y., Ng, T.B., Au, S.W. Biochem. J. (2006)