Gene Review:
KCNIP1 - Kv channel interacting protein 1
Homo sapiens
Synonyms:
A-type potassium channel modulatory protein 1, KCHIP1, KChIP1, Kv channel-interacting protein 1, Potassium channel-interacting protein 1, ...
- Two N-terminal domains of Kv4 K(+) channels regulate binding to and modulation by KChIP1. Scannevin, R.H., Wang, K., Jow, F., Megules, J., Kopsco, D.C., Edris, W., Carroll, K.C., Lü, Q., Xu, W., Xu, Z., Katz, A.H., Olland, S., Lin, L., Taylor, M., Stahl, M., Malakian, K., Somers, W., Mosyak, L., Bowlby, M.R., Chanda, P., Rhodes, K.J. Neuron (2004)
- Traffic of Kv4 K+ channels mediated by KChIP1 is via a novel post-ER vesicular pathway. Hasdemir, B., Fitzgerald, D.J., Prior, I.A., Tepikin, A.V., Burgoyne, R.D. J. Cell Biol. (2005)
- Residues within the myristoylation motif determine intracellular targeting of the neuronal Ca2+ sensor protein KChIP1 to post-ER transport vesicles and traffic of Kv4 K+ channels. O'Callaghan, D.W., Hasdemir, B., Leighton, M., Burgoyne, R.D. J. Cell. Sci. (2003)
- Evidence showing an intermolecular interaction between KChIP proteins and Taiwan cobra cardiotoxins. Lin, Y.L., Lin, S.R., Wu, T.T., Chang, L.S. Biochem. Biophys. Res. Commun. (2004)
- Elucidating KChIP effects on Kv4.3 inactivation and recovery kinetics with a minimal KChIP2 isoform. Patel, S.P., Campbell, D.L., Strauss, H.C. J. Physiol. (Lond.) (2002)
- Experimental study on the new significant function domains of KCHIP1 protein. Liu, Z., Xiao, X.J., Fan, F.Y., Sun, Y.M., Li, Y.M., Yang, F.J. Sheng li xue bao [Acta physiologica Sinica]. (2005)
- Contributions of sustained INa and IKv43 to transmural heterogeneity of early repolarization and arrhythmogenesis in canine left ventricular myocytes. Flaim, S.N., Giles, W.R., McCulloch, A.D. Am. J. Physiol. Heart Circ. Physiol. (2006)
- High-affinity interaction of the N-terminal myristoylation motif of the neuronal calcium sensor protein hippocalcin with phosphatidylinositol 4,5-bisphosphate. O'Callaghan, D.W., Haynes, L.P., Burgoyne, R.D. Biochem. J. (2005)
- Identification and characterization of small molecule modulators of KChIP/Kv4 function. Bowlby, M.R., Chanda, P., Edris, W., Hinson, J., Jow, F., Katz, A.H., Kennedy, J., Krishnamurthy, G., Pitts, K., Ryan, K., Zhang, H., Greenblatt, L. Bioorg. Med. Chem. (2005)
- Phenotypic differences in transient outward K+ current of human and canine ventricular myocytes: insights into molecular composition of ventricular Ito. Akar, F.G., Wu, R.C., Deschenes, I., Armoundas, A.A., Piacentino, V., Houser, S.R., Tomaselli, G.F. Am. J. Physiol. Heart Circ. Physiol. (2004)