Gene Review:
NT5C - 5', 3'-nucleotidase, cytosolic
Homo sapiens
Synonyms:
5'(3')-deoxyribonucleotidase, cytosolic type, Cytosolic 5',3'-pyrimidine nucleotidase, DNT, DNT-1, DNT1, ...
- Evidence for essential catalytic determinants for human erythrocyte pyrimidine 5'-nucleotidase. Amici, A., Ciccioli, K., Naponelli, V., Raffaelli, N., Magni, G. Cell. Mol. Life Sci. (2005)
- Hemoglobin adducts in workers exposed to nitrotoluenes. Jones, C.R., Liu, Y.Y., Sepai, O., Yan, H., Sabbioni, G. Carcinogenesis (2005)
- The glioma cell-derived neurite promoting activity protein is functionally and immunologically related to human protease nexin-I. Knauer, D.J., Orlando, R.A., Rosenblatt, D. J. Cell. Physiol. (1987)
- Biochemical and genetic evidence for meta-ring cleavage of 2,4, 5-trihydroxytoluene in Burkholderia sp. strain DNT. Haigler, B.E., Johnson, G.R., Suen, W.C., Spain, J.C. J. Bacteriol. (1999)
- Aerobic and anaerobic toluene degradation by a newly isolated denitrifying bacterium, Thauera sp. strain DNT-1. Shinoda, Y., Sakai, Y., Uenishi, H., Uchihashi, Y., Hiraishi, A., Yukawa, H., Yurimoto, H., Kato, N. Appl. Environ. Microbiol. (2004)
- Triptans for migraine therapy: a comparison based on number needed to treat and doses needed to treat. Mullins, C.D., Weis, K.A., Perfetto, E.M., Subedi, P.R., Healey, P.J. Journal of managed care pharmacy : JMCP. (2005)
- Protease-nexin I as an androgen-dependent secretory product of the murine seminal vesicle. Vassalli, J.D., Huarte, J., Bosco, D., Sappino, A.P., Sappino, N., Velardi, A., Wohlwend, A., Ernø, H., Monard, D., Belin, D. EMBO J. (1993)
- A deoxyribonucleotidase in mitochondria: involvement in regulation of dNTP pools and possible link to genetic disease. Rampazzo, C., Gallinaro, L., Milanesi, E., Frigimelica, E., Reichard, P., Bianchi, V. Proc. Natl. Acad. Sci. U.S.A. (2000)
- Immunophenotypic profiles in families with autoimmune lymphoproliferative syndrome. Bleesing, J.J., Brown, M.R., Straus, S.E., Dale, J.K., Siegel, R.M., Johnson, M., Lenardo, M.J., Puck, J.M., Fleisher, T.A. Blood (2001)
- Purification and sequence analysis of 4-methyl-5-nitrocatechol oxygenase from Burkholderia sp. strain DNT. Haigler, B.E., Suen, W.C., Spain, J.C. J. Bacteriol. (1996)
- Saturation mutagenesis of 2,4-DNT dioxygenase of Burkholderia sp. strain DNT for enhanced dinitrotoluene degradation. Leungsakul, T., Keenan, B.G., Yin, H., Smets, B.F., Wood, T.K. Biotechnol. Bioeng. (2005)
- TNT and nitroaromatic compounds are chemoattractants for Burkholderia cepacia R34 and Burkholderia sp. strain DNT. Leungsakul, T., Keenan, B.G., Smets, B.F., Wood, T.K. Appl. Microbiol. Biotechnol. (2005)
- Assignment of the human gene for uridine 5'-monophosphate phosphohydrolase (UMPH2) to the long arm of chromosome 17. Wilson, D.E., Swallow, D.M., Povey, S. Ann. Hum. Genet. (1986)
- Protease nexin I, thrombin- and urokinase-inhibiting serpin, concentrated in normal human cerebrospinal fluid. Festoff, B.W., Rao, J.S., Chen, M. Neurology (1992)
- Biomarkers of exposure, effect, and susceptibility in workers exposed to nitrotoluenes. Sabbioni, G., Jones, C.R., Sepai, O., Hirvonen, A., Norppa, H., Järventaus, H., Glatt, H., Pomplun, D., Yan, H., Brooks, L.R., Warren, S.H., Demarini, D.M., Liu, Y.Y. Cancer Epidemiol. Biomarkers Prev. (2006)
- Mouse cytosolic and mitochondrial deoxyribonucleotidases: cDNA cloning of the mitochondrial enzyme, gene structures, chromosomal mapping and comparison with the human orthologs. Rampazzo, C., Kost-Alimova, M., Ruzzenente, B., Dumanski, J.P., Bianchi, V. Gene (2002)
- Cytosolic high K(m) 5'-nucleotidase and 5'(3')-deoxyribonucleotidase in substrate cycles involved in nucleotide metabolism. Gazziola, C., Ferraro, P., Moras, M., Reichard, P., Bianchi, V. J. Biol. Chem. (2001)
- Peripheral blood lymphocytes in SLE--hyperexpression of CD154 on T and B lymphocytes and increased number of double negative T cells. Devi, B.S., Van Noordin, S., Krausz, T., Davies, K.A. J. Autoimmun. (1998)
- Pyrimidine nucleotidases/phosphotransferases from human erythrocyte. Amici, A., Emanuelli, M., Raffaelli, N., Ruggieri, S., Magni, G. Nucleosides Nucleotides (1999)
- Protease nexins: cell-secreted proteins that mediate the binding, internalization, and degradation of regulatory serine proteases. Knauer, D.J., Thompson, J.A., Cunningham, D.D. J. Cell. Physiol. (1983)
- Determination of nitroaromatic compounds in air samples at femtogram level using C18 membrane sampling and on-line extraction with LC-MS. Sánchez, C., Carlsson, H., Colmsjö, A., Crescenzi, C., Batlle, R. Anal. Chem. (2003)
- Human erythrocyte pyrimidine 5'-nucleotidase isoenzymes: effect of sulfhydryl reagents and electrophoretic discrimination. Manco, L., Amorim, A. Electrophoresis (1993)
- Cytosolic and mitochondrial deoxyribonucleotidases: activity with substrate analogs, inhibitors and implications for therapy. Mazzon, C., Rampazzo, C., Scaini, M.C., Gallinaro, L., Karlsson, A., Meier, C., Balzarini, J., Reichard, P., Bianchi, V. Biochem. Pharmacol. (2003)
- 5'-(3')-nucleotidase mRNA levels in blast cells are a prognostic factor in acute myeloid leukemia patients treated with cytarabine. Galmarini, C.M., Cros, E., Graham, K., Thomas, X., Mackey, J.R., Dumontet, C. Haematologica (2004)
- Human erythrocyte pyrimidine 5'-nucleotidase, PN-I. Amici, A., Magni, G. Arch. Biochem. Biophys. (2002)