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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Gene: Vps26a
-
vacuolar protein sorting 26 homolog A (yeast)
Mus musculus
Synonyms: AA407240, H58 protein, HB58, H beta 58, mVPS26, Vacuolar protein sorting 26, vacuolar protein sorting 26 (yeast), Vacuolar protein sorting-associated protein 26A, Vesicle protein sorting 26, Vesicle protein sorting 26A, Vps26
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By Day 12, the fetal vasculature extended into the placental labyrinth, and the erythroid stem cells continued to strongly express H beta 58[1].
The expression pattern of H beta maternal and fetal placental tissues and its early expression in fetal erythroid stem cells during formation and maturation of the chorioallantoic placenta suggest that H beta 58 plays key roles in the regulatory networks that control hematopoietic development and placentation[1].
Immunoreactive H beta 58 localized to erythroid cells within the developing fetal vasculature of the chorioallantoic primordia at Day 10 of pregnancy [1].
Immunodetection in the early postimplantation uterus (Days 6-8 of pregnancy) showed H beta 58 localized in the luminal and glandular epithelia and some stromal cells[1].
Stable cell lines (HRP/LRP) isolated from the rat labyrinthine placenta expressed H beta 58 mRNA and protein [1].
H beta 58 mutant embryonic stem cells are clearly pluripotent but they appear to be more restricted in their developmental potential, suggesting that the H beta 58 gene product may be required by specific tissues of the embryo [3].
The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.
