Gene Review:
ICAM2 - intercellular adhesion molecule 2
Homo sapiens
Synonyms:
CD102, ICAM-2, Intercellular adhesion molecule 2
- A functional integrin ligand on the surface of platelets: intercellular adhesion molecule-2. Diacovo, T.G., deFougerolles, A.R., Bainton, D.F., Springer, T.A. J. Clin. Invest. (1994)
- Intercellular adhesion molecules (ICAM)-1 ICAM-2 and ICAM-3 function as counter-receptors for lymphocyte function-associated molecule 1 in human immunodeficiency virus-mediated syncytia formation. Butini, L., De Fougerolles, A.R., Vaccarezza, M., Graziosi, C., Cohen, D.I., Montroni, M., Springer, T.A., Pantaleo, G., Fauci, A.S. Eur. J. Immunol. (1994)
- Beta2 integrin/ICAM expression in Crohn's disease. Bernstein, C.N., Sargent, M., Gallatin, W.M. Clin. Immunol. Immunopathol. (1998)
- DC-SIGN binds to HIV-1 glycoprotein 120 in a distinct but overlapping fashion compared with ICAM-2 and ICAM-3. Su, S.V., Hong, P., Baik, S., Negrete, O.A., Gurney, K.B., Lee, B. J. Biol. Chem. (2004)
- EBV peptide epitope sensitization restores human cytotoxic T cell recognition of Burkitt's lymphoma cells. Evidence for a critical role for ICAM-2. Khanna, R., Burrows, S.R., Suhrbier, A., Jacob, C.A., Griffin, H., Misko, I.S., Sculley, T.B., Rowe, M., Rickinson, A.B., Moss, D.J. J. Immunol. (1993)
- Expression of intercellular adhesion molecule 1 (ICAM-1) in Alzheimer's disease. Frohman, E.M., Frohman, T.C., Gupta, S., de Fougerolles, A., van den Noort, S. J. Neurol. Sci. (1991)
- Crystal structure of ICAM-2 reveals a distinctive integrin recognition surface. Casasnovas, J.M., Springer, T.A., Liu, J.H., Harrison, S.C., Wang, J.H. Nature (1997)
- Activation of the PKB/AKT pathway by ICAM-2. Perez, O.D., Kinoshita, S., Hitoshi, Y., Payan, D.G., Kitamura, T., Nolan, G.P., Lorens, J.B. Immunity (2002)
- DC-SIGN-ICAM-2 interaction mediates dendritic cell trafficking. Geijtenbeek, T.B., Krooshoop, D.J., Bleijs, D.A., van Vliet, S.J., van Duijnhoven, G.C., Grabovsky, V., Alon, R., Figdor, C.G., van Kooyk, Y. Nat. Immunol. (2000)
- Expression of adhesion molecules and chemotactic cytokines in cultured human mesothelial cells. Jonjić, N., Peri, G., Bernasconi, S., Sciacca, F.L., Colotta, F., Pelicci, P., Lanfrancone, L., Mantovani, A. J. Exp. Med. (1992)
- A monoclonal antibody to the human leukocyte adhesion molecule intercellular adhesion molecule-2. Cellular distribution and molecular characterization of the antigen. Nortamo, P., Salcedo, R., Timonen, T., Patarroyo, M., Gahmberg, C.G. J. Immunol. (1991)
- The human ICAM2 gene maps to 17q23-25. Sansom, D., Borrow, J., Solomon, E., Trowsdale, J. Genomics (1991)
- Lymphocyte function-associated antigen-1 binding residues in intercellular adhesion molecule-2 (ICAM-2) and the integrin binding surface in the ICAM subfamily. Casasnovas, J.M., Pieroni, C., Springer, T.A. Proc. Natl. Acad. Sci. U.S.A. (1999)
- {alpha}-Chain phosphorylation of the human leukocyte CD11b/CD18 (Mac-1) integrin is pivotal for integrin activation to bind ICAMs and leukocyte extravasation. Fagerholm, S.C., Varis, M., Stefanidakis, M., Hilden, T.J., Gahmberg, C.G. Blood (2006)
- Contribution of N-linked glycans to the conformation and function of intercellular adhesion molecules (ICAMs). Jiménez, D., Roda-Navarro, P., Springer, T.A., Casasnovas, J.M. J. Biol. Chem. (2005)
- Expression of ICAM-R (ICAM-3), a novel counter-receptor for LFA-1, in rheumatoid and nonrheumatoid synovium. Comparison with other adhesion molecules. el-Gabalawy, H., Gallatin, M., Vazeux, R., Peterman, G., Wilkins, J. Arthritis Rheum. (1994)
- Intercellular adhesion molecule-3 is the predominant co-stimulatory ligand for leukocyte function antigen-1 on human blood dendritic cells. Starling, G.C., McLellan, A.D., Egner, W., Sorg, R.V., Fawcett, J., Simmons, D.L., Hart, D.N. Eur. J. Immunol. (1995)
- Retinoic acid induces aggregation of the acute promyelocytic leukemia cell line NB-4 by utilization of LFA-1 and ICAM-2. Larson, R.S., Brown, D.C., Sklar, L.A. Blood (1997)
- Distribution of immunoglobulin superfamily members ICAM-1, -2, -3, and the beta 2 integrin LFA-1 in multiple sclerosis lesions. Bö, L., Peterson, J.W., Mørk, S., Hoffman, P.A., Gallatin, W.M., Ransohoff, R.M., Trapp, B.D. J. Neuropathol. Exp. Neurol. (1996)
- Aceclofenac, a new nonsteroidal antiinflammatory drug, decreases the expression and function of some adhesion molecules on human neutrophils. González-Alvaro, I., Carmona, L., Díaz-González, F., González-Amaro, R., Mollinedo, F., Sánchez-Madrid, F., Laffón, A., García-Vicuña, R. J. Rheumatol. (1996)
- Neutrophil accumulation on activated, surface-adherent platelets in flow is mediated by interaction of Mac-1 with fibrinogen bound to alphaIIbbeta3 and stimulated by platelet-activating factor. Weber, C., Springer, T.A. J. Clin. Invest. (1997)
- Intercellular adhesion molecule-2 (CD102) binds to the leukocyte integrin CD11b/CD18 through the A domain. Xie, J., Li, R., Kotovuori, P., Vermot-Desroches, C., Wijdenes, J., Arnaout, M.A., Nortamo, P., Gahmberg, C.G. J. Immunol. (1995)
- Intercellular adhesion molecule-2, a second counter-receptor for CD11a/CD18 (leukocyte function-associated antigen-1), provides a costimulatory signal for T-cell receptor-initiated activation of human T cells. Damle, N.K., Klussman, K., Aruffo, A. J. Immunol. (1992)
- A peptide derived from the intercellular adhesion molecule-2 regulates the avidity of the leukocyte integrins CD11b/CD18 and CD11c/CD18. Li, R., Xie, J., Kantor, C., Koistinen, V., Altieri, D.C., Nortamo, P., Gahmberg, C.G. J. Cell Biol. (1995)
- Crystallographic characterization of the radixin FERM domain bound to the cytoplasmic tail of the adhesion protein ICAM-2. Hamada, K., Shimizu, T., Matsui, T., Tsukita, S., Tsukita, S., Hakoshima, T. Acta Crystallogr. D Biol. Crystallogr. (2001)
- Functional intercellular adhesion molecule-3 is expressed by freshly isolated epidermal Langerhans cells and is not regulated during culture. Zambruno, G., Cossarizza, A., Zacchi, V., Ottani, D., Luppi, A.M., Giannetti, A., Girolomoni, G. J. Invest. Dermatol. (1995)
- Tumor necrosis factor (TNF)-alpha and interleukin (IL)-1beta down-regulate intercellular adhesion molecule (ICAM)-2 expression on the endothelium. McLaughlin, F., Hayes, B.P., Horgan, C.M., Beesley, J.E., Campbell, C.J., Randi, A.M. Cell Adhes. Commun. (1998)
- The pig analogue of CD59 protects transgenic mouse hearts from injury by human complement. Fisicaro, N., Aminian, A., Hinchliffe, S.J., Morgan, B.P., Pearse, M.J., D'Apice, A.J., Cowan, P.J. Transplantation (2000)
- Adhesion receptor profile of thymic B-cell lymphoma. Eichelmann, A., Koretz, K., Mechtersheimer, G., Möller, P. Am. J. Pathol. (1992)
- Binding sites of leukocyte beta 2 integrins (LFA-1, Mac-1) on the human ICAM-4/LW blood group protein. Hermand, P., Huet, M., Callebaut, I., Gane, P., Ihanus, E., Gahmberg, C.G., Cartron, J.P., Bailly, P. J. Biol. Chem. (2000)
- Neurofibromatosis 2 tumor suppressor protein colocalizes with ezrin and CD44 and associates with actin-containing cytoskeleton. Sainio, M., Zhao, F., Heiska, L., Turunen, O., den Bakker, M., Zwarthoff, E., Lutchman, M., Rouleau, G.A., Jääskeläinen, J., Vaheri, A., Carpén, O. J. Cell. Sci. (1997)
- Inhibitory effect of clarithromycin on costimulatory molecule expression and cytokine production by synovial fibroblast-like cells. Matsuoka, N., Eguchi, K., Kawakami, A., Tsuboi, M., Kawabe, Y., Aoyagi, T., Nagataki, S. Clin. Exp. Immunol. (1996)
- Microglia in the human fetal spinal cord--patterns of distribution, morphology and phenotype. Rezaie, P., Patel, K., Male, D.K. Brain Res. Dev. Brain Res. (1999)
- Intercellular adhesion molecule-2 (ICAM-2) expression on human dendritic cells. Hart, D.N., Prickett, T.C. Cell. Immunol. (1993)
- The human leukocyte-adhesion ligand, intercellular-adhesion molecule 2. Expression and characterization of the protein. Gahmberg, C.G., Nortamo, P., Zimmermann, D., Ruoslahti, E. Eur. J. Biochem. (1991)
- Ezrin/radixin/moesin (ERM) proteins bind to a positively charged amino acid cluster in the juxta-membrane cytoplasmic domain of CD44, CD43, and ICAM-2. Yonemura, S., Hirao, M., Doi, Y., Takahashi, N., Kondo, T., Tsukita, S., Tsukita, S. J. Cell Biol. (1998)