Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Javascript disabled

Please enable Javascript support in your browser to use this application.

Instructions on how to enable JavaScript on different browsers can be found here: http://www.google.com/support/bin/answer.py?answer=23852.

[edit this page]

Gene Review:

myoC - class I myosin

Dictyostelium discoideum AX4

Temesvari, L.A. et al., De La Roche, M.A. et al.

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on myoC

No alteration in contractile vacuole structure or function was observed in the myoB-, myoC- or myoB-/C- cell lines [1].
Sequence analysis of the MyoD light chain showed it to be a unique protein, termed MlcD, that shares 44% sequence identity with Dictyostelium calmodulin and 43% sequence identity with Acanthamoeba castellanii myosin IC light chain [2].

Biological context of myoC

Various properties of the endosomal pathway in the myoB-/C- double mutant as well as in the myoB- and myoC- single mutants, including intravesicular pH, and intracellular retention time and exocytosis of a fluid phase marker, were found to be indistinguishable from wild-type parental cells [1].

References

Examination of the endosomal and lysosomal pathways in Dictyostelium discoideum myosin I mutants. Temesvari, L.A., Bush, J.M., Peterson, M.D., Novak, K.D., Titus, M.A., Cardelli, J.A. J. Cell. Sci. (1996) [Pubmed]
The Dictyostelium class I myosin, MyoD, contains a novel light chain that lacks high-affinity calcium-binding sites. De La Roche, M.A., Lee, S.F., Côté, G.P. Biochem. J. (2003) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use

[search][advanced]