The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.
wikigene or wiki gene protein drug chemical gene disease author authorship tracking evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
Gene Review: 

Socs36E  -  Suppressor of cytokine signaling at 36E

Drosophila melanogaster

 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text.

Ideally this entry shall become one comprehensive and continuous article. Bulleted lists, for instance, were only used because it is impossible to automatically integrate independent facts into a continuous text.

Much of the current information on this page has been automatically compiled from Pubmed.

This precompiled information serves as a substrate and matrix to embed your contributions, but it is by no means the final word - Homo sapiens can do much better!

WikiGenes is a non-profit and open access community project.

 

 

High impact information on Socs36E

  • Socs36E is expressed zygotically, predominantly during embryogenesis, in a highly dynamic pattern [1].
  • In vivo expression of SOCS36E in transgenic flies results in several adult phenotypes [1].
  • Cloning and expression of Drosophila SOCS36E and its potential regulation by the JAK/STAT pathway [2].
  • Examination of one Drosophila SOCS homologue, Socs36E, demonstrated that its expression is responsive to JAK pathway activity and it is capable of downregulating JAK signaling, similar to the well characterized mammalian SOCS [3].

References

  1. SOCS36E, a novel Drosophila SOCS protein, suppresses JAK/STAT and EGF-R signalling in the imaginal wing disc. Callus, B.A., Mathey-Prevot, B. Oncogene (2002)
  2. Cloning and expression of Drosophila SOCS36E and its potential regulation by the JAK/STAT pathway. Karsten, P., Häder, S., Zeidler, M.P. Mech. Dev. (2002)
  3. Two Drosophila suppressors of cytokine signaling (SOCS) differentially regulate JAK and EGFR pathway activities. Rawlings, J.S., Rennebeck, G., Harrison, S.M., Xi, R., Harrison, D.A. BMC Cell Biol. (2004)
 
 
 
 
 
 
 
[search][advanced]

Editor

Links

Table of contents