Gene Review:
IL16 - interleukin 16
Homo sapiens
Synonyms:
FLJ16806, FLJ42735, HsT19289, IL-16, LCF, ...
Kurth,
Mahajan,
Tavares,
Blaschke,
Brabeck,
Reich,
Sampaio,
Norley,
Schluesener,
Kurth,
Asomuddinov,
Vollhardt,
de Oliveira,
Baier,
Schwartz,
Mendes,
Kim,
Hewitt,
Xavier,
König,
Neumann,
Guo,
Bannert,
Mittelbronn,
Heine,
Werner,
Whitney,
Haag,
Middel,
Mueller,
Nair,
Yujun Zhang,
Marina Tuzova,
Zhi-Xiong J. Xiao,
William W. Cruikshank,
David M. Center,
Bannert,
Lang,
Hugo,
- Nef triggers a transcriptional program in T cells imitating single-signal T cell activation and inducing HIV virulence mediators. Simmons, A., Aluvihare, V., McMichael, A. Immunity (2001)
- Association of allergic contact dermatitis with a promoter polymorphism in the IL16 gene. Reich, K., Westphal, G., König, I.R., Mössner, R., Krüger, U., Ziegler, A., Neumann, C., Schnuch, A. J. Allergy Clin. Immunol. (2003)
- The maturation-dependent production of interleukin-16 is impaired in monocyte-derived dendritic cells from atopic dermatitis patients but is restored by inflammatory cytokines TNF-alpha and IL-1beta. Reich, K., Hugo, S., Middel, P., Blaschke, V., Heine, A., Neumann, C. Exp. Dermatol. (2004)
- IL-16 represses HIV-1 promoter activity. Maciaszek, J.W., Parada, N.A., Cruikshank, W.W., Center, D.M., Kornfeld, H., Viglianti, G.A. J. Immunol. (1997)
- IL-16 is critical for Tropheryma whipplei replication in Whipple's disease. Desnues, B., Raoult, D., Mege, J.L. J. Immunol. (2005)
- Association of drug abuse with inhibition of HIV-1 immune responses: studies with long-term of HIV-1 non-progressors. Nair, M.P., Mahajan, S., Hewitt, R., Whitney, Z.R., Schwartz, S.A. J. Neuroimmunol. (2004)
- Early clinical predictive factors during coma recovery. Formisano, R., Bivona, U., Penta, F., Giustini, M., Buzzi, M.G., Ciurli, P., Matteis, M., Barba, C., Della Vedova, C., Vinicola, V., Taggi, F. Acta Neurochir. Suppl. (2005)
- Human CD4+ cells transfected with IL-16 cDNA are resistant to HIV-1 infection: inhibition of mRNA expression. Zhou, P., Goldstein, S., Devadas, K., Tewari, D., Notkins, A.L. Nat. Med. (1997)
- CD4-mediated stimulation of human eosinophils: lymphocyte chemoattractant factor and other CD4-binding ligands elicit eosinophil migration. Rand, T.H., Cruikshank, W.W., Center, D.M., Weller, P.F. J. Exp. Med. (1991)
- Expression of interleukin-16 by microglial cells in inflammatory, autoimmune, and degenerative lesions of the rat brain. Guo, L.H., Mittelbronn, M., Brabeck, C., Mueller, C.A., Schluesener, H.J. J. Neuroimmunol. (2004)
- IL-16- and other CD4 ligand-induced migration is dependent upon protein kinase C. Parada, N.A., Cruikshank, W.W., Danis, H.L., Ryan, T.C., Center, D.M. Cell. Immunol. (1996)
- Assignment of human interleukin 16 (IL16) to chromosome 15q26.3 by radiation hybrid mapping. Kim, H.S. Cytogenet. Cell Genet. (1999)
- Molecular cloning, sequence, expression, and processing of the interleukin 16 precursor. Baier, M., Bannert, N., Werner, A., Lang, K., Kurth, R. Proc. Natl. Acad. Sci. U.S.A. (1997)
- Human and mouse mast cells use the tetraspanin CD9 as an alternate interleukin-16 receptor. Qi, J.C., Wang, J., Mandadi, S., Tanaka, K., Roufogalis, B.D., Madigan, M.C., Lai, K., Yan, F., Chong, B.H., Stevens, R.L., Krilis, S.A. Blood (2006)
- Molecular and functional analysis of a lymphocyte chemoattractant factor: association of biologic function with CD4 expression. Cruikshank, W.W., Center, D.M., Nisar, N., Wu, M., Natke, B., Theodore, A.C., Kornfeld, H. Proc. Natl. Acad. Sci. U.S.A. (1994)
- PDZ Domain-mediated interaction of interleukin-16 precursor proteins with myosin phosphatase targeting subunits. Bannert, N., Vollhardt, K., Asomuddinov, B., Haag, M., König, H., Norley, S., Kurth, R. J. Biol. Chem. (2003)
- GA-binding protein factors, in concert with the coactivator CREB binding protein/p300, control the induction of the interleukin 16 promoter in T lymphocytes. Bannert, N., Avots, A., Baier, M., Serfling, E., Kurth, R. Proc. Natl. Acad. Sci. U.S.A. (1999)
- Structure of interleukin 16 resembles a PDZ domain with an occluded peptide binding site. Mühlhahn, P., Zweckstetter, M., Georgescu, J., Ciosto, C., Renner, C., Lanzendörfer, M., Lang, K., Ambrosius, D., Baier, M., Kurth, R., Holak, T.A. Nat. Struct. Biol. (1998)
- A role for IL-16 in the cross-talk between dendritic cells and T cells. Kaser, A., Dunzendorfer, S., Offner, F.A., Ryan, T., Schwabegger, A., Cruikshank, W.W., Wiedermann, C.J., Tilg, H. J. Immunol. (1999)
- The CD4-associated tyrosine kinase p56lck is required for lymphocyte chemoattractant factor-induced T lymphocyte migration. Ryan, T.C., Cruikshank, W.W., Kornfeld, H., Collins, T.L., Center, D.M. J. Biol. Chem. (1995)
- Pro-IL-16 recruits histone deacetylase 3 to the Skp2 core promoter through interaction with transcription factor GABP. Zhang, Y., Tuzova, M., Xiao, Z.X., Cruikshank, W.W., Center, D.M. J. Immunol. (2008)
- The synthesis by fine-needle aspiration biopsy cultures of IL-7, IL-16 and IL-18 is significantly associated with acute rejection in kidney transplants. de Oliveira, J.G., Xavier, P.D., Sampaio, S.M., Tavares, I.S., Mendes, A.A. Nephron (2002)
- Enhanced concentrations of interleukin 16 are associated with joint destruction in patients with rheumatoid arthritis. Lard, L.R., Roep, B.O., Toes, R.E., Huizinga, T.W. J. Rheumatol. (2004)
- Interleukin-12 and interleukin-16 in periodontal disease. Tsai, I.S., Tsai, C.C., Ho, Y.P., Ho, K.Y., Wu, Y.M., Hung, C.C. Cytokine (2005)
- Identification of a CD4 domain required for interleukin-16 binding and lymphocyte activation. Liu, Y., Cruikshank, W.W., O'Loughlin, T., O'Reilly, P., Center, D.M., Kornfeld, H. J. Biol. Chem. (1999)