Gene Review:
ITIH4 - inter-alpha-trypsin inhibitor heavy chain...
Homo sapiens
Synonyms:
GP120, Gp120, H4P, IHRP, ITI heavy chain H4, ...
Brooke,
McLaughlin,
Cortopassi,
Sapolsky,
Balzarini,
Van Laethem,
Hatse,
Froeyen,
Peumans,
Van Damme,
Schols,
Harraghy,
Mitchell,
Miller,
Geleziunas,
Bianchi,
Lennard,
Hrin,
Zhang,
Lu,
An,
Ingallinella,
Finotto,
Mattu,
Finnefrock,
Bramhill,
Cook,
Eckert,
Hampton,
Patel,
Jarantow,
Joyce,
Ciliberto,
Cortese,
Lu,
Strohl,
Schleif,
McElhaugh,
Lane,
Lloyd,
Lowe,
Osbourn,
Vaughan,
Emini,
Barbato,
Kim,
Hazuda,
Shiver,
Pessi,
Stefano,
Salzet,
Rialas,
Mattocks,
Fimiani,
Bilfinger,
Yusa,
Maeda,
Fujioka,
Monde,
Harada,
Fung,
Yip,
Lomas,
Wang,
Yip,
Meng,
Lin,
Zhang,
Zhang,
Chan,
Weinberger,
Piñeiro,
Alava,
González-Ramón,
Osada,
Lasierra,
Larrad,
Piñeiro,
Lampreave,
Diarra-Mehrpour,
Sarafan,
Bourguignon,
Bonnet,
Bost,
Martin,
- Hypercholesterolemia associated with splice-junction variation of inter-alpha-trypsin inhibitor heavy chain 4 (ITIH4) gene. Fujita, Y., Ezura, Y., Emi, M., Sato, K., Takada, D., Iino, Y., Katayama, Y., Takahashi, K., Kamimura, K., Bujo, H., Saito, Y. J. Hum. Genet. (2004)
- Classification of cancer types by measuring variants of host response proteins using SELDI serum assays. Fung, E.T., Yip, T.T., Lomas, L., Wang, Z., Yip, C., Meng, X.Y., Lin, S., Zhang, F., Zhang, Z., Chan, D.W., Weinberger, S.R. Int. J. Cancer (2005)
- ITIH4 serum concentration increases during acute-phase processes in human patients and is up-regulated by interleukin-6 in hepatocarcinoma HepG2 cells. Piñeiro, M., Alava, M.A., González-Ramón, N., Osada, J., Lasierra, P., Larrad, L., Piñeiro, A., Lampreave, F. Biochem. Biophys. Res. Commun. (1999)
- A human monoclonal antibody neutralizes diverse HIV-1 isolates by binding a critical gp41 epitope. Miller, M.D., Geleziunas, R., Bianchi, E., Lennard, S., Hrin, R., Zhang, H., Lu, M., An, Z., Ingallinella, P., Finotto, M., Mattu, M., Finnefrock, A.C., Bramhill, D., Cook, J., Eckert, D.M., Hampton, R., Patel, M., Jarantow, S., Joyce, J., Ciliberto, G., Cortese, R., Lu, P., Strohl, W., Schleif, W., McElhaugh, M., Lane, S., Lloyd, C., Lowe, D., Osbourn, J., Vaughan, T., Emini, E., Barbato, G., Kim, P.S., Hazuda, D.J., Shiver, J.W., Pessi, A. Proc. Natl. Acad. Sci. U.S.A. (2005)
- Inhibition of functional properties of tetanus antigen-specific T-cell clones by envelope glycoprotein GP120 of human immunodeficiency virus. Chirmule, N., Kalyanaraman, V.S., Oyaizu, N., Slade, H.B., Pahwa, S. Blood (1990)
- Effect of GP120 on glutathione peroxidase activity in cortical cultures and the interaction with steroid hormones. Brooke, S.M., McLaughlin, J.R., Cortopassi, K.M., Sapolsky, R.M. J. Neurochem. (2002)
- Molecular mimicry between the rabies virus glycoprotein and human immunodeficiency virus-1 GP120: cross-reacting antibodies induced by rabies vaccination. Bracci, L., Ballas, S.K., Spreafico, A., Neri, P. Blood (1997)
- Carbohydrate-binding agents cause deletions of highly conserved glycosylation sites in HIV GP120: a new therapeutic concept to hit the achilles heel of HIV. Balzarini, J., Van Laethem, K., Hatse, S., Froeyen, M., Peumans, W., Van Damme, E., Schols, D. J. Biol. Chem. (2005)
- Isolation of TAK-779-resistant HIV-1 from an R5 HIV-1 GP120 V3 loop library. Yusa, K., Maeda, Y., Fujioka, A., Monde, K., Harada, S. J. Biol. Chem. (2005)
- Antigenic properties of peptide mimotopes of HIV-1-associated carbohydrate antigens. Pashov, A., Canziani, G., Monzavi-Karbassi, B., Kaveri, S.V., Macleod, S., Saha, R., Perry, M., Vancott, T.C., Kieber-Emmons, T. J. Biol. Chem. (2005)
- Brucella abortus conjugated with a gp120 or V3 loop peptide derived from human immunodeficiency virus (HIV) type 1 induces neutralizing anti-HIV antibodies, and the V3-B. abortus conjugate is effective even after CD4+ T-cell depletion. Golding, B., Inman, J., Highet, P., Blackburn, R., Manischewitz, J., Blyveis, N., Angus, R.D., Golding, H. J. Virol. (1995)
- Interferon-gamma decreases cell surface expression of galactosyl ceramide, the receptor for HIV-1 GP120 on human colonic epithelial cells. Yahi, N., Spitalnik, S.L., Stefano, K.A., De Micco, P., Gonzalez-Scarano, F., Fantini, J. Virology (1994)
- Role of the V2, V3, and CD4-binding domains of GP120 in curdlan sulfate neutralization sensitivity of HIV-1 during infection of T lymphocytes. Jagodzinski, P.P., Wustner, J., Kmieciak, D., Wasik, T.J., Fertala, A., Sieron, A.L., Takahashi, M., Tsuji, T., Mimura, T., Fung, M.S., Gorny, M.K., Kloczewiak, M., Kaneko, Y., Kozbor, D. Virology (1996)
- Macrophage behavior associated with acute and chronic exposure to HIV GP120, morphine and anandamide: endothelial implications. Stefano, G.B., Salzet, M., Rialas, C.M., Mattocks, D., Fimiani, C., Bilfinger, T.V. International journal of cardiology. (1998)
- BIP co-chaperone MTJ1/ERDJ1 interacts with inter-alpha-trypsin inhibitor heavy chain 4. Kroczynska, B., King-Simmons, L., Alloza, L., Alava, M.A., Elguindi, E.C., Blond, S.Y. Biochem. Biophys. Res. Commun. (2005)
- The H4P heavy chain of inter-alpha-inhibitor family largely differs in the structure and synthesis of its prolin-rich region from rat to human. Soury, E., Olivier, E., Daveau, M., Hiron, M., Claeyssens, S., Risler, J.L., Salier, J.P. Biochem. Biophys. Res. Commun. (1998)
- Isolation and characterization of the promoter and partial enhancer region of the porcine inter-alpha-trypsin inhibitor heavy chain 4 gene. Harraghy, N., Mitchell, T.J. Clin. Diagn. Lab. Immunol. (2005)
- Increased immunogenicity of human immunodeficiency virus gp120 engineered to express Galalpha1-3Galbeta1-4GlcNAc-R epitopes. Abdel-Motal, U., Wang, S., Lu, S., Wigglesworth, K., Galili, U. J. Virol. (2006)
- Rapid in vivo induction of HIV-specific CD8+ cytotoxic T lymphocytes by a 15-amino acid unmodified free peptide from the immunodominant V3-loop of GP120. Sastry, K.J., Nehete, P.N., Venkatnarayanan, S., Morkowski, J., Platsoucas, C.D., Arlinghaus, R.B. Virology (1992)
- Intracerebral injection of human immunodeficiency virus type 1 coat glycoprotein GP120 does not produce neurodegeneration in rats. Bagetta, G., Finazzi-Agrò, A., Palma, E., Nisticò, G. Neurosci. Lett. (1994)
- Cloning and characterization of cDNA for inter-alpha-trypsin inhibitor family heavy chain-related protein (IHRP), a novel human plasma glycoprotein. Saguchi, K., Tobe, T., Hashimoto, K., Sano, Y., Nakano, Y., Miura, N.H., Tomita, M. J. Biochem. (1995)
- Stimulation of protein tyrosine phosphorylation, phosphoinositide turnover, and multiple previously unidentified serine/threonine-specific protein kinases by the Pan-B-cell receptor CD40/Bp50 at discrete developmental stages of human B-cell ontogeny. Uckun, F.M., Schieven, G.L., Dibirdik, I., Chandan-Langlie, M., Tuel-Ahlgren, L., Ledbetter, J.A. J. Biol. Chem. (1991)
- Sulfation of the human immunodeficiency virus envelope glycoprotein. Bernstein, H.B., Compans, R.W. J. Virol. (1992)
- Current use of anti-HIV drugs in AIDS. Clumeck, N. J. Antimicrob. Chemother. (1993)
- Human inter-alpha-trypsin inhibitor heavy chain H3 gene. Genomic organization, promoter analysis, and gene linkage. Diarra-Mehrpour, M., Sarafan, N., Bourguignon, J., Bonnet, F., Bost, F., Martin, J.P. J. Biol. Chem. (1998)
- Purification and characterization of a novel glycoprotein which has significant homology to heavy chains of inter-alpha-trypsin inhibitor family from human plasma. Choi-Miura, N.H., Sano, Y., Oda, E., Nakano, Y., Tobe, T., Yanagishita, T., Taniyama, M., Katagiri, T., Tomita, M. J. Biochem. (1995)
- Role of CD4 hinge region in GP120 utilization by immunoglobulin domain 1. Murray, J.L., Hu, Q.X., Navenot, J.M., Peiper, S.C. Biochem. Biophys. Res. Commun. (2002)
- Peptide T blocks GP120/CCR5 chemokine receptor-mediated chemotaxis. Redwine, L.S., Pert, C.B., Rone, J.D., Nixon, R., Vance, M., Sandler, B., Lumpkin, M.D., Dieter, D.J., Ruff, M.R. Clin. Immunol. (1999)
- Quantification of fragments of human serum inter-alpha-trypsin inhibitor heavy chain 4 by a surface-enhanced laser desorption/ionization-based immunoassay. Song, J., Patel, M., Rosenzweig, C.N., Chan-Li, Y., Sokoll, L.J., Fung, E.T., Choi-Miura, N.H., Goggins, M., Chan, D.W., Zhang, Z. Clin. Chem. (2006)
- Assignment of the porcine inter-alpha trypsin inhibitor heavy chain 4 (ITIH4) gene to SSC13q2.1-->q2.2 by fluorescence in situ hybridization and radiation hybrid mapping. Kuiper, H., Spötter, A., Drögemüller, C., Brenig, B., Leeb, T., Distl, O. Cytogenet. Cell Genet. (2001)
- Mapping of human inter-alpha-trypsin inhibitor family heavy chain-related protein gene (ITIHL1) to human chromosome 3p21-->p14. Tobe, T., Saguchi, K., Hashimoto, K., Miura, N.H., Tomita, M., Li, F., Wang, Y., Minoshima, S., Shimizu, N. Cytogenet. Cell Genet. (1995)