Gene Review:
J2R - temporal expression: early
Vaccinia virus
- Fine structure analysis and nucleotide sequence of the vaccinia virus thymidine kinase gene. Hruby, D.E., Maki, R.A., Miller, D.B., Ball, L.A. Proc. Natl. Acad. Sci. U.S.A. (1983)
- Similar genetic organization between a region of fowlpox virus DNA and the vaccinia virus HindIII J fragment despite divergent location of the thymidine kinase gene. Drillien, R., Spehner, D., Villeval, D., Lecocq, J.P. Virology (1987)
- Distinct thymidine kinases encoded by cowpox virus and herpes simplex virus contribute significantly to the differential antiviral activity of nucleoside analogs. Prichard, M.N., Williams, A.D., Keith, K.A., Harden, E.A., Kern, E.R. Antiviral Res. (2006)
- Prevention of vaccinia virus infection in immunodeficient mice by vector-directed IL-2 expression. Flexner, C., Hügin, A., Moss, B. Nature (1987)
- Epitopes derived by incidental translational frameshifting give rise to a protective CTL response. Zook, M.B., Howard, M.T., Sinnathamby, G., Atkins, J.F., Eisenlohr, L.C. J. Immunol. (2006)
- A single amino acid substitution abolishes feedback inhibition of vaccinia virus thymidine kinase. Black, M.E., Hruby, D.E. J. Biol. Chem. (1992)
- The nucleotide sequence of the chicken thymidine kinase gene and the relationship of its predicted polypeptide to that of the vaccinia virus thymidine kinase. Kwoh, T.J., Engler, J.A. Nucleic Acids Res. (1984)
- Dominant negative selection of vaccinia virus using a thymidine kinase/thymidylate kinase fusion gene and the prodrug azidothymidine. Holzer, G.W., Mayrhofer, J., Gritschenberger, W., Falkner, F.G. Virology (2005)
- Inhibition of vaccinia virus thymidine kinase by the distal products of its own metabolic pathway. Hruby, D.E. Virus Res. (1985)
- Nucleotide sequence of the vaccinia virus thymidine kinase gene and the nature of spontaneous frameshift mutations. Weir, J.P., Moss, B. J. Virol. (1983)
- Dominant host range selection of vaccinia recombinants by rescue of an essential gene. Holzer, G.W., Gritschenberger, W., Mayrhofer, J.A., Wieser, V., Dorner, F., Falkner, F.G. Virology (1998)
- Synthesis of vaccinia virus thymidine kinase in microinjected Xenopus oocytes. Hruby, D.E., Miller, D.B., Ball, L.A. Virology (1982)
- Site-directed mutagenesis of a conserved domain in vaccinia virus thymidine kinase. Evidence for a potential role in magnesium binding. Black, M.E., Hruby, D.E. J. Biol. Chem. (1992)
- Introduction of foreign DNA into the vaccinia virus genome by in vitro ligation: recombination-independent selectable cloning vectors. Merchlinsky, M., Moss, B. Virology (1992)
- Quaternary structure of vaccinia virus thymidine kinase. Black, M.E., Hruby, D.E. Biochem. Biophys. Res. Commun. (1990)
- Expression and single-step purification of enzymatically active vaccinia virus thymidine kinase containing an engineered oligohistidine domain by immobilized metal affinity chromatography. Franke, C.A., Hruby, D.E. Protein Expr. Purif. (1993)