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Gene Review

Sac1  -  CG9128 gene product from transcript CG9128-RB

Drosophila melanogaster

Synonyms: CG9128, Dmel\CG9128, Phosphatidylinositide phosphatase SAC1, Sacm1l, Suppressor of actin mutations 1-like protein, ...
 
 
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High impact information on Sac1

  • The Sac1 lipid phosphatase regulates cell shape change and the JNK cascade during dorsal closure in Drosophila [1].
  • The Sac1 lipid phosphatase dephosphorylates several phosphatidylinositol (PtdIns) phosphates and, in yeast, regulates a diverse range of cellular processes including organization of the actin cytoskeleton and secretion [1].
  • Six essential complementation groups were assigned to specific genes, including genes encoding a porphobilinogen deaminase and a Sac1-like protein [2].

References

  1. The Sac1 lipid phosphatase regulates cell shape change and the JNK cascade during dorsal closure in Drosophila. Wei, H.C., Sanny, J., Shu, H., Baillie, D.L., Brill, J.A., Price, J.V., Harden, N. Curr. Biol. (2003) [Pubmed]
  2. Functional genomic analysis of the 61D-61F region of the third chromosome of Drosophila melanogaster. Wei, H.C., Shu, H., Price, J.V. Genome (2003) [Pubmed]
 
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