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Gene Review: 

C2CD4B  -  C2 calcium-dependent domain containing 4B

Homo sapiens

Synonyms: C2 calcium-dependent domain-containing protein 4B, FAM148B, NLF2, Nuclear-localized factor 2, Protein FAM148B
 
 
 
 
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High impact information on NLF2

  • We propose that NLF1 and NLF2 belong to a novel gene family encoding nuclear factors with a role in regulating genes which control cellular architecture [1].
 

Anatomical context of NLF2

  • NLF1 and NLF2 transcripts were found predominantly in endothelial cells, and the encoded proteins were localised to the nuclear compartment suggesting a role in the regulation of transcription [1].

References

  1. A novel gene family induced by acute inflammation in endothelial cells. Warton, K., Foster, N.C., Gold, W.A., Stanley, K.K. Gene (2004) [Pubmed]
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