Gene Review:
LAD1 - ladinin 1
Homo sapiens
Synonyms:
LAD, LADA, Lad-1, Ladinin-1, Linear IgA disease antigen
- The 97 kDa linear IgA bullous dermatosis antigen is not expressed in a patient with generalized atrophic benign epidermolysis bullosa with a novel homozygous G258X mutation in COL17A1. Shimizu, H., Takizawa, Y., Pulkkinen, L., Zone, J.J., Matsumoto, K., Saida, T., Uitto, J., Nishikawa, T. J. Invest. Dermatol. (1998)
- LAD-1, the linear IgA bullous dermatosis autoantigen, is a novel 120-kDa anchoring filament protein synthesized by epidermal cells. Marinkovich, M.P., Taylor, T.B., Keene, D.R., Burgeson, R.E., Zone, J.J. J. Invest. Dermatol. (1996)
- Isolated disease of left anterior descending coronary artery. Angiocardiographic and clinical study of 218 patients. Brooks, N., Cattell, M., Jennings, K., Balcon, R., Honey, M., Layton, C. British heart journal. (1982)
- LAD-1 is absent in a subset of junctional epidermolysis bullosa patients. Marinkovich, M.P., Tran, H.H., Rao, S.K., Giudice, G.J., Balding, S., Jonkman, M.F., Pas, H.H., McGuire, J.S., Herron, G.S., Bruckner-Tuderman, L. J. Invest. Dermatol. (1997)
- Autoantibodies in a subgroup of patients with linear IgA disease react with the NC16A domain of BP1801. Zillikens, D., Herzele, K., Georgi, M., Schmidt, E., Chimanovitch, I., Schumann, H., Mascaro, J.M., Diaz, L.A., Bruckner-Tuderman, L., Bröcker, E.B., Giudice, G.J. J. Invest. Dermatol. (1999)
- Performance in the cross-maze and slip funnel tests of four pairs of rat lines selectively bred for divergent alcohol drinking behavior. Salimov, R.M., McBride, W.J., Sinclair, J.D., Lumeng, L., Li, T. Addiction biology. (1996)
- A novel leukocyte adhesion deficiency caused by expressed but nonfunctional beta2 integrins Mac-1 and LFA-1. Hogg, N., Stewart, M.P., Scarth, S.L., Newton, R., Shaw, J.M., Law, S.K., Klein, N. J. Clin. Invest. (1999)
- Dysfunctional LAD-1 neutrophils and colitis. Uzel, G., Kleiner, D.E., Kuhns, D.B., Holland, S.M. Gastroenterology (2001)
- Molecular complexity of the cutaneous basement membrane zone. Uitto, J., Pulkkinen, L. Mol. Biol. Rep. (1996)
- Pain thresholds in alcohol preferring and non-preferring rats: diurnal and repeated trial line differences. Kimpel, M.W., Brown, M.M., Froehlich, J.C. Alcohol. Clin. Exp. Res. (2003)
- Bullous pemphigoid antigen II (BP180) and its soluble extracellular domains are major autoantigens in mucous membrane pemphigoid: the pathogenic relevance to HLA class II alleles and disease severity. Oyama, N., Setterfield, J.F., Powell, A.M., Sakuma-Oyama, Y., Albert, S., Bhogal, B.S., Vaughan, R.W., Kaneko, F., Challacombe, S.J., Black, M.M. Br. J. Dermatol. (2006)
- BP180 (type XVII collagen) and its role in cutaneous biology and disease. Van den Bergh, F., Giudice, G.J. Advances in dermatology. (2003)
- Loss of flow-dependent coronary artery dilatation in patients with hypertension. Antony, I., Lerebours, G., Nitenberg, A. Circulation (1995)
- CD18 in Monogenic and Polygenic Inflammatory Processes of the Skin. Peters, T., Sindrilaru, A., Wang, H., Oreshkova, T., Renkl, A.C., Kess, D., Scharffetter-Kochanek, K. J. Invest. Dermatol. (2006)
- Effects of neuropeptide Y on sucrose and ethanol intake and on anxiety-like behavior in high alcohol drinking (HAD) and low alcohol drinking (LAD) rats. Badia-Elder, N.E., Stewart, R.B., Powrozek, T.A., Murphy, J.M., Li, T.K. Alcohol. Clin. Exp. Res. (2003)
- Migration of CD18-deficient neutrophils in vitro: evidence for a CD18-independent pathway induced by IL-8. Morland, C.M., Morland, B.J., Darbyshire, P.J., Stockley, R.A. Biochim. Biophys. Acta (2000)
- 97 kDa linear IgA bullous dermatosis antigen localizes in the lamina lucida between the NC16A and carboxyl terminal domains of the 180 kDa bullous pemphigoid antigen. Ishiko, A., Shimizu, H., Masunaga, T., Yancey, K.B., Giudice, G.J., Zone, J.J., Nishikawa, T. J. Invest. Dermatol. (1998)
- Type XVII collagen (BP180) and LAD-1 are present as separate trimeric complexes. Pas, H.H., Kloosterhuis, G.J., Nijenhuis, M., de Jong, M.C., van der Meer, J.B., Jonkman, M.F. J. Invest. Dermatol. (1999)
- Localized bullous pemphigoid in a patient with B-cell lymphoma. Egan, C.A., Florell, S.R., Zone, J.J. South. Med. J. (1999)