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Gene Review

mib1  -  mind bomb 1

Drosophila melanogaster

Synonyms: CG5841, D-mib, D-mib1, Dmel\CG5841, Dmib, ...
 
 
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High impact information on mib1

  • Here, we present evidence that the Drosophila ortholog of Mib (Dmib) is required for ubiquitination and signaling activity of DSL ligands in cells that normally do not express Neur, and can be functionally replaced by ectopically expressed Neur [1].
  • During wing development, expression of D-mib in dorsal cells appears to be necessary and sufficient for wing margin specification, indicating that D-mib also regulates Ser signaling [2].
 

Biological context of mib1

  • Moreover, the activity of the D-mib gene is required for the endocytosis of Ser in wing imaginal disc cells [2].

References

 
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