Gene Review:
E2f1 - E2F transcription factor 1
Rattus norvegicus
Synonyms:
E2F-1, Transcription factor E2F1
- Transactivation of E2F-regulated genes by polyomavirus large T antigen: evidence for a two-step mechanism. Nemethova, M., Smutny, M., Wintersberger, E. Mol. Cell. Biol. (2004)
- Synergistic gene expressions of cyclin E, cdk2, cdk5 and E2F-1 during the prolactin-induced G1/S transition in rat Nb2 pre-T lymphoma cells. Hosokawa, Y., Yang, M., Kaneko, S., Tanaka, M., Nakashima, K. Biochem. Mol. Biol. Int. (1995)
- Inhibition of DNA synthesis by RB: effects on G1/S transition and S-phase progression. Knudsen, E.S., Buckmaster, C., Chen, T.T., Feramisco, J.R., Wang, J.Y. Genes Dev. (1998)
- Anoxic fibroblasts activate a replication checkpoint that is bypassed by E1a. Gardner, L.B., Li, F., Yang, X., Dang, C.V. Mol. Cell. Biol. (2003)
- Effect of energy restriction on cell cycle machinery in 1-methyl-1-nitrosourea-induced mammary carcinomas in rats. Jiang, W., Zhu, Z., Thompson, H.J. Cancer Res. (2003)
- Tumor-selective transgene expression in vivo mediated by an E2F-responsive adenoviral vector. Parr, M.J., Manome, Y., Tanaka, T., Wen, P., Kufe, D.W., Kaelin, W.G., Fine, H.A. Nat. Med. (1997)
- Regulation of neuron survival and death by p130 and associated chromatin modifiers. Liu, D.X., Nath, N., Chellappan, S.P., Greene, L.A. Genes Dev. (2005)
- Regulation of neuronal survival and death by E2F-dependent gene repression and derepression. Liu, D.X., Greene, L.A. Neuron (2001)
- Role of c-fos and E2F in the induction of cyclin A transcription and vascular smooth muscle cell proliferation. Sylvester, A.M., Chen, D., Krasinski, K., Andrés, V. J. Clin. Invest. (1998)
- E2Fs link the control of G1/S and G2/M transcription. Zhu, W., Giangrande, P.H., Nevins, J.R. EMBO J. (2004)
- Local delivery of E2F decoy oligodeoxynucleotides using ultrasound with microbubble agent (Optison) inhibits intimal hyperplasia after balloon injury in rat carotid artery model. Hashiya, N., Aoki, M., Tachibana, K., Taniyama, Y., Yamasaki, K., Hiraoka, K., Makino, H., Yasufumi, K., Ogihara, T., Morishita, R. Biochem. Biophys. Res. Commun. (2004)
- Hyperglycemia enhances VSMC proliferation with NF-kappaB activation by angiotensin II and E2F-1 augmentation by growth factors. Fujita, N., Furukawa, Y., Du, J., Itabashi, N., Fujisawa, G., Okada, K., Saito, T., Ishibashi, S. Mol. Cell. Endocrinol. (2002)
- E1A can provoke G1 exit that is refractory to p21 and independent of activating cdk2. Akli, S., Zhan, S., Abdellatif, M., Schneider, M.D. Circ. Res. (1999)
- Ursodeoxycholic acid modulates E2F-1 and p53 expression through a caspase-independent mechanism in transforming growth factor beta1-induced apoptosis of rat hepatocytes. Sola, S., Ma, X., Castro, R.E., Kren, B.T., Steer, C.J., Rodrigues, C.M. J. Biol. Chem. (2003)
- 2-acetaminofluorene blocks cell cycle progression after hepatectomy by p21 induction and lack of cyclin E expression. Trautwein, C., Will, M., Kubicka, S., Rakemann, T., Flemming, P., Manns, M.P. Oncogene (1999)
- Roles of E2F1 in mesangial cell proliferation in vitro. Inoshita, S., Terada, Y., Nakashima, O., Kuwahara, M., Sasaki, S., Marumo, F. Kidney Int. (1999)
- Differences in E2F subunit expression in quiescent and proliferating vascular smooth muscle cells. Fujita, N., Furukawa, Y., Itabashi, N., Okada, K., Saito, T., Ishibashi, S. Am. J. Physiol. Heart Circ. Physiol. (2002)
- E2F1-specific induction of apoptosis and p53 accumulation, which is blocked by Mdm2. Kowalik, T.F., DeGregori, J., Leone, G., Jakoi, L., Nevins, J.R. Cell Growth Differ. (1998)
- Mitoinhibitory effects of the tumor promoter 2-acetylaminofluorene in rat liver: loss of E2F-1 and E2F-3 expression and cdk 2 kinase activity in late G1. Ohlson, L.C., Koroxenidou, L., Porsch-Hällström, I. J. Hepatol. (2004)
- Inhibition of the E2F-1/p53/Bax pathway by tauroursodeoxycholic acid in amyloid beta-peptide-induced apoptosis of PC12 cells. Ramalho, R.M., Ribeiro, P.S., Solá, S., Castro, R.E., Steer, C.J., Rodrigues, C.M. J. Neurochem. (2004)
- Modulation of nuclear steroid receptors by ursodeoxycholic acid inhibits TGF-beta1-induced E2F-1/p53-mediated apoptosis of rat hepatocytes. Solá, S., Castro, R.E., Kren, B.T., Steer, C.J., Rodrigues, C.M. Biochemistry (2004)
- Differential activation of cyclin and cyclin-dependent kinase genes by adenovirus E1A12S cDNA product. Ishii, T., Shimizu, M., Kanayama, Y., Nakada, S., Nojima, H., Oda, K. Exp. Cell Res. (1993)
- Deregulated expression of E2F-1 induces cyclin A- and E-associated kinase activities independently from cell cycle position. Soucek, T., Pusch, O., Hengstschläger-Ottnad, E., Adams, P.D., Hengstschläger, M. Oncogene (1997)
- Activation of Cdk2-pRB-E2F1 cell cycle pathway by repeated electroconvulsive shock in the rat frontal cortex. Kim, Y., Seo, M.S., Kang, U.G., Yoon, S.C., Ahn, Y.M., Kim, Y.S., Juhnn, Y.S. Biol. Psychiatry (2005)
- Cell cycle deregulation in liver lesions of rats with and without genetic predisposition to hepatocarcinogenesis. Pascale, R.M., Simile, M.M., De Miglio, M.R., Muroni, M.R., Calvisi, D.F., Asara, G., Casabona, D., Frau, M., Seddaiu, M.A., Feo, F. Hepatology (2002)
- pRb and p107 regulate E2F activity during lens fiber cell differentiation. Rampalli, A.M., Gao, C.Y., Chauthaiwale, V.M., Zelenka, P.S. Oncogene (1998)
- A gene therapy strategy using a transcription factor decoy of the E2F binding site inhibits smooth muscle proliferation in vivo. Morishita, R., Gibbons, G.H., Horiuchi, M., Ellison, K.E., Nakama, M., Zhang, L., Kaneda, Y., Ogihara, T., Dzau, V.J. Proc. Natl. Acad. Sci. U.S.A. (1995)