Gene Review:
bcd - bicoid
Drosophila melanogaster
Synonyms:
BCD, BG:DS00276.7, Bcd, CG1034, Dmel\CG1034, ...
- Heads or tails: host-parasite interactions in the Drosophila-Wolbachia system. Veneti, Z., Clark, M.E., Karr, T.L., Savakis, C., Bourtzis, K. Appl. Environ. Microbiol. (2004)
- RNA loop-loop interactions as dynamic functional motifs. Brunel, C., Marquet, R., Romby, P., Ehresmann, C. Biochimie (2002)
- RNA nanotechnology: engineering, assembly and applications in detection, gene delivery and therapy. Guo, P. Journal of nanoscience and nanotechnology. (2005)
- Evaluation of the antibacterial spectrum of drosocin analogues. Bikker, F.J., Kaman-van Zanten, W.E., de Vries-van de Ruit, A.M., Voskamp-Visser, I., van Hooft, P.A., Mars-Groenendijk, R.H., de Visser, P.C., Noort, D. Chemical biology & drug design. (2006)
- A new paradigm for translational control: inhibition via 5'-3' mRNA tethering by Bicoid and the eIF4E cognate 4EHP. Cho, P.F., Poulin, F., Cho-Park, Y.A., Cho-Park, I.B., Chicoine, J.D., Lasko, P., Sonenberg, N. Cell (2005)
- In vivo analysis of Drosophila bicoid mRNA localization reveals a novel microtubule-dependent axis specification pathway. Cha, B.J., Koppetsch, B.S., Theurkauf, W.E. Cell (2001)
- The Drosophila homolog of C. elegans PAR-1 organizes the oocyte cytoskeleton and directs oskar mRNA localization to the posterior pole. Shulman, J.M., Benton, R., St Johnston, D. Cell (2000)
- Staufen protein associates with the 3'UTR of bicoid mRNA to form particles that move in a microtubule-dependent manner. Ferrandon, D., Elphick, L., Nüsslein-Volhard, C., St Johnston, D. Cell (1994)
- Synergy between the hunchback and bicoid morphogens is required for anterior patterning in Drosophila. Simpson-Brose, M., Treisman, J., Desplan, C. Cell (1994)
- Implications for bcd mRNA localization from spatial distribution of exu protein in Drosophila oogenesis. Wang, S., Hazelrigg, T. Nature (1994)
- Mediation of Drosophila head development by gap-like segmentation genes. Cohen, S.M., Jürgens, G. Nature (1990)
- Regulation of even-skipped stripe 2 in the Drosophila embryo. Small, S., Blair, A., Levine, M. EMBO J. (1992)
- Bicoid cooperative DNA binding is critical for embryonic patterning in Drosophila. Lebrecht, D., Foehr, M., Smith, E., Lopes, F.J., Vanario-Alonso, C.E., Reinitz, J., Burz, D.S., Hanes, S.D. Proc. Natl. Acad. Sci. U.S.A. (2005)
- The molecular motor dynein is involved in targeting swallow and bicoid RNA to the anterior pole of Drosophila oocytes. Schnorrer, F., Bohmann, K., Nüsslein-Volhard, C. Nat. Cell Biol. (2000)
- Persistence of Hunchback in the terminal region of the Drosophila blastoderm embryo impairs anterior development. Janody, F., Reischl, J., Dostatni, N. Development (2000)
- Differential regulation of the two transcripts from the Drosophila gap segmentation gene hunchback. Schröder, C., Tautz, D., Seifert, E., Jäckle, H. EMBO J. (1988)
- Mutations that perturb poly(A)-dependent maternal mRNA activation block the initiation of development. Lieberfarb, M.E., Chu, T., Wreden, C., Theurkauf, W., Gergen, J.P., Strickland, S. Development (1996)
- The solution structure of the native K50 Bicoid homeodomain bound to the consensus TAATCC DNA-binding site. Baird-Titus, J.M., Clark-Baldwin, K., Dave, V., Caperelli, C.A., Ma, J., Rance, M. J. Mol. Biol. (2006)
- Small circular DNA in Drosophila melanogaster. Stanfield, S., Helinski, D.R. Cell (1976)
- Reprogrammable recognition codes in bicoid homeodomain-DNA interaction. Dave, V., Zhao, C., Yang, F., Tung, C.S., Ma, J. Mol. Cell. Biol. (2000)
- Regulation of inositol 1,4,5-trisphosphate 3-kinases by calcium and localization in cells. Lloyd-Burton, S.M., Yu, J.C., Irvine, R.F., Schell, M.J. J. Biol. Chem. (2007)
- Enhancer sequences influence the role of the amino-terminal domain of bicoid in transcription. Fu, D., Zhao, C., Ma, J. Mol. Cell. Biol. (2003)
- Sequences outside the homeodomain of bicoid are required for protein-protein interaction. Yuan, D., Ma, X., Ma, J. J. Biol. Chem. (1996)
- DSP1 interacts with bicoid for knirps enhancement. Daulny, A., Rappailles, A., Landemarre, L., Locker, D., Decoville, M. Genesis (2003)
- The role of localization of bicoid RNA in organizing the anterior pattern of the Drosophila embryo. Berleth, T., Burri, M., Thoma, G., Bopp, D., Richstein, S., Frigerio, G., Noll, M., Nüsslein-Volhard, C. EMBO. J. (1988)
- The bicoid protein determines position in the Drosophila embryo in a concentration-dependent manner. Driever, W., Nüsslein-Volhard, C. Cell. (1988)
- The gradient morphogen bicoid is a concentration-dependent transcriptional activator. Struhl, G., Struhl, K., Macdonald, P.M. Cell. (1989)
- Target selectivity of bicoid is dependent on nonconsensus site recognition and protein-protein interaction. Zhao, C., Dave, V., Yang, F., Scarborough, T., Ma, J. Mol. Cell. Biol. (2000)
- Reprogrammable recognition codes in bicoid homeodomain-DNA interaction. Dave, V., Zhao, C., Yang, F., Tung, C.S., Ma, J. Mol. Cell. Biol. (2000)
- Sequences outside the homeodomain of bicoid are required for protein-protein interaction. Yuan, D., Ma, X., Ma, J. J. Biol. Chem. (1996)
- Aromatic amino acids are critical for stability of the bicoid homeodomain. Subramaniam, V., Jovin, T.M., Rivera-Pomar, R.V. J. Biol. Chem. (2001)
- The Drosophila morphogenetic protein Bicoid binds DNA cooperatively. Ma, X., Yuan, D., Diepold, K., Scarborough, T., Ma, J. Development. (1996)
- Cooperative DNA-binding by Bicoid provides a mechanism for threshold-dependent gene activation in the Drosophila embryo. Burz, D.S., Rivera-Pomar, R., Jäckle, H., Hanes, S.D. EMBO. J. (1998)
- Isolation of mutations that disrupt cooperative DNA binding by the Drosophila bicoid protein. Burz, D.S., Hanes, S.D. J. Mol. Biol. (2001)
- Par-1 regulates bicoid mRNA localisation by phosphorylating Exuperantia. Riechmann, V., Ephrussi, A. Development (2004)
- Protein encoded by the exuperantia gene is concentrated at sites of bicoid mRNA accumulation in Drosophila nurse cells but not in oocytes or embryos. Macdonald, P.M., Luk, S.K., Kilpatrick, M. Genes Dev. (1991)
- RNA regulatory elements mediate control of Drosophila body pattern by the posterior morphogen nanos. Wharton, R.P., Struhl, G. Cell (1991)
- A morphogenetic gradient of hunchback protein organizes the expression of the gap genes Krüppel and knirps in the early Drosophila embryo. Hülskamp, M., Pfeifle, C., Tautz, D. Nature (1990)
- An anterior function for the Drosophila posterior determinant Pumilio. Gamberi, C., Peterson, D.S., He, L., Gottlieb, E. Development (2002)
- The co-activator CREB-binding protein participates in enhancer-dependent activities of bicoid. Fu, D., Wen, Y., Ma, J. J. Biol. Chem. (2004)
- RNA binding and translational suppression by bicoid. Rivera-Pomar, R., Niessing, D., Schmidt-Ott, U., Gehring, W.J., Jäckle, H. Nature (1996)
- Establishment of developmental precision and proportions in the early Drosophila embryo. Houchmandzadeh, B., Wieschaus, E., Leibler, S. Nature (2002)
- Competition for overlapping sites in the regulatory region of the Drosophila gene Krüppel. Hoch, M., Gerwin, N., Taubert, H., Jäckle, H. Science (1992)
- Phosphorylation of bicoid on MAP-kinase sites: contribution to its interaction with the torso pathway. Janody, F., Sturny, R., Catala, F., Desplan, C., Dostatni, N. Development (2000)
- The role of localization of bicoid RNA in organizing the anterior pattern of the Drosophila embryo. Berleth, T., Burri, M., Thoma, G., Bopp, D., Richstein, S., Frigerio, G., Noll, M., Nüsslein-Volhard, C. EMBO J. (1988)
- Targeting gene expression to the head: the Drosophila orthodenticle gene is a direct target of the Bicoid morphogen. Gao, Q., Finkelstein, R. Development (1998)
- Identification of drosophila bicoid-interacting proteins using a custom two-hybrid selection. Zhu, W., Hanes, S.D. Gene (2000)
- Functional colocalization of ribozymes and target mRNAs in Drosophila oocytes. Lee, N.S., Sun, B., Williamson, R., Gunkel, N., Salvaterra, P.M., Rossi, J.J. FASEB J. (2001)