Gene Review:
osk - oskar
Drosophila melanogaster
Synonyms:
CG10901, Dm-osk, Dmel\CG10901, Maternal effect protein oskar, OSK, ...
- Heads or tails: host-parasite interactions in the Drosophila-Wolbachia system. Veneti, Z., Clark, M.E., Karr, T.L., Savakis, C., Bourtzis, K. Appl. Environ. Microbiol. (2004)
- Oskar gains weight. Ryder, S.P. Nat. Struct. Mol. Biol. (2006)
- Bruno acts as a dual repressor of oskar translation, promoting mRNA oligomerization and formation of silencing particles. Chekulaeva, M., Hentze, M.W., Ephrussi, A. Cell (2006)
- The Drosophila SDE3 homolog armitage is required for oskar mRNA silencing and embryonic axis specification. Cook, H.A., Koppetsch, B.S., Wu, J., Theurkauf, W.E. Cell (2004)
- The Drosophila homolog of C. elegans PAR-1 organizes the oocyte cytoskeleton and directs oskar mRNA localization to the posterior pole. Shulman, J.M., Benton, R., St Johnston, D. Cell (2000)
- Translational regulation of oskar mRNA by bruno, an ovarian RNA-binding protein, is essential. Kim-Ha, J., Kerr, K., Macdonald, P.M. Cell (1995)
- MOESIN crosslinks actin and cell membrane in Drosophila oocytes and is required for OSKAR anchoring. Jankovics, F., Sinka, R., Lukácsovich, T., Erdélyi, M. Curr. Biol. (2002)
- The Drosophila hnRNPA/B homolog, Hrp48, is specifically required for a distinct step in osk mRNA localization. Huynh, J.R., Munro, T.P., Smith-Litière, K., Lepesant, J.A., St Johnston, D. Dev. Cell (2004)
- Rab11 polarization of the Drosophila oocyte: a novel link between membrane trafficking, microtubule organization, and oskar mRNA localization and translation. Dollar, G., Struckhoff, E., Michaud, J., Cohen, R.S. Development (2002)
- Kinesin I-dependent cortical exclusion restricts pole plasm to the oocyte posterior. Cha, B.J., Serbus, L.R., Koppetsch, B.S., Theurkauf, W.E. Nat. Cell Biol. (2002)
- Barentsz is essential for the posterior localization of oskar mRNA and colocalizes with it to the posterior pole. van Eeden, F.J., Palacios, I.M., Petronczki, M., Weston, M.J., St Johnston, D. J. Cell Biol. (2001)
- Control of oskar mRNA translation by Bruno in a novel cell-free system from Drosophila ovaries. Castagnetti, S., Hentze, M.W., Ephrussi, A., Gebauer, F. Development (2000)
- Localization-dependent oskar protein accumulation; control after the initiation of translation. Braat, A.K., Yan, N., Arn, E., Harrison, D., Macdonald, P.M. Dev. Cell (2004)
- The receptor-like tyrosine phosphatase lar is required for epithelial planar polarity and for axis determination within drosophila ovarian follicles. Frydman, H.M., Spradling, A.C. Development (2001)
- Oskar protein interaction with Vasa represents an essential step in polar granule assembly. Breitwieser, W., Markussen, F.H., Horstmann, H., Ephrussi, A. Genes Dev. (1996)
- Bruno regulates gurken during Drosophila oogenesis. Filardo, P., Ephrussi, A. Mech. Dev. (2003)
- Smaug, a novel RNA-binding protein that operates a translational switch in Drosophila. Dahanukar, A., Walker, J.A., Wharton, R.P. Mol. Cell (1999)
- Premature translation of oskar in oocytes lacking the RNA-binding protein bicaudal-C. Saffman, E.E., Styhler, S., Rother, K., Li, W., Richard, S., Lasko, P. Mol. Cell. Biol. (1998)
- A function for kinesin I in the posterior transport of oskar mRNA and Staufen protein. Brendza, R.P., Serbus, L.R., Duffy, J.B., Saxton, W.M. Science (2000)
- The actin-binding protein Lasp promotes Oskar accumulation at the posterior pole of the Drosophila embryo. Suyama, R., Jenny, A., Curado, S., Pellis-van Berkel, W., Ephrussi, A. Development (2009)
- Squid is required for efficient posterior localization of oskar mRNA during Drosophila oogenesis. Norvell, A., Debec, A., Finch, D., Gibson, L., Thoma, B. Dev. Genes Evol. (2005)
- Drosophila cup is an eIF4E binding protein that associates with Bruno and regulates oskar mRNA translation in oogenesis. Nakamura, A., Sato, K., Hanyu-Nakamura, K. Dev. Cell (2004)
- Dynein and the actin cytoskeleton control kinesin-driven cytoplasmic streaming in Drosophila oocytes. Serbus, L.R., Cha, B.J., Theurkauf, W.E., Saxton, W.M. Development (2005)
- Roles of Bifocal, Homer, and F-actin in anchoring Oskar to the posterior cortex of Drosophila oocytes. Babu, K., Cai, Y., Bahri, S., Yang, X., Chia, W. Genes Dev. (2004)
- aubergine enhances oskar translation in the Drosophila ovary. Wilson, J.E., Connell, J.E., Macdonald, P.M. Development (1996)
- Oskar allows nanos mRNA translation in Drosophila embryos by preventing its deadenylation by Smaug/CCR4. Zaessinger, S., Busseau, I., Simonelig, M. Development (2006)
- Parcas, a regulator of non-receptor tyrosine kinase signaling, acts during anterior-posterior patterning and somatic muscle development in Drosophila melanogaster. Beckett, K., Baylies, M.K. Dev. Biol. (2006)
- An oskar-dependent positive feedback loop maintains the polarity of the Drosophila oocyte. Zimyanin, V., Lowe, N., St Johnston, D. Curr. Biol. (2007)
- Drosophila Y14 shuttles to the posterior of the oocyte and is required for oskar mRNA transport. Hachet, O., Ephrussi, A. Curr. Biol. (2001)
- Functional colocalization of ribozymes and target mRNAs in Drosophila oocytes. Lee, N.S., Sun, B., Williamson, R., Gunkel, N., Salvaterra, P.M., Rossi, J.J. FASEB J. (2001)
- Abdominal segmentation, pole cell formation, and embryonic polarity require the localized activity of oskar, a maternal gene in Drosophila. Lehmann, R., Nüsslein-Volhard, C. Cell (1986)
- oskar gene expression in the vector mosquitoes, Anopheles gambiae and Aedes aegypti. Juhn, J., James, A.A. Insect Mol. Biol. (2006)
- Molecular beacons: Fluorescent probes for detection of endogenous mRNAs in living cells. Bratu, D.P. Methods Mol. Biol. (2006)