High impact information on milt

• A likely explanation of the apparent trafficking defect is offered by the coimmunoprecipitation of Milton and kinesin heavy chain [1].
• Milton protein is associated with mitochondria and is present primarily in axons and synapses [1].
• Photoreceptors mutant for milton show aberrant synaptic transmission despite normal phototransduction [1].
• Without Milton, synaptic terminals and axons lack mitochondria, although mitochondria are numerous in neuronal cell bodies [1].
• The recruitment of KHC to mitochondria is, in part, determined by the NH(2) terminus-splicing variant of milton [2].

Biological context of milt

• Axonal transport of mitochondria to synapses depends on milton, a novel Drosophila protein [1].

Anatomical context of milt

• Milton controls the early acquisition of mitochondria by Drosophila oocytes [3].

References