Gene Review:
MYL2 - myosin, light chain 2, regulatory, cardiac...
Homo sapiens
Synonyms:
CMH10, MLC-2, MLC-2v, MLC2, Myosin regulatory light chain 2, ventricular/cardiac muscle isoform
- Interaction of a conserved peptide domain in recombinant human ventricular myosin light chain-2 with myosin heavy chain. Wadgaonkar, R., Shafiq, S., Rajmanickam, C., Siddiqui, M.A. Cell. Mol. Biol. Res. (1993)
- A ternary complex of transcription factors, Nishéd and NFATc4, and co-activator p300 bound to an intronic sequence, intronic regulatory element, is pivotal for the up-regulation of myosin light chain-2v gene in cardiac hypertrophy. Mathew, S., Mascareno, E., Siddiqui, M.A. J. Biol. Chem. (2004)
- A P19Cl6 GFP reporter line to quantify cardiomyocyte differentiation of stem cells. Moore, J.C., Spijker, R., Martens, A.C., de Boer, T., Rook, M.B., van der Heyden, M.A., Tertoolen, L.G., Mummery, C.L. Int. J. Dev. Biol. (2004)
- Endosomes generate localized Rho-ROCK-MLC2-based contractile signals via Endo180 to promote adhesion disassembly. Sturge, J., Wienke, D., Isacke, C.M. J. Cell Biol. (2006)
- Adeno-associated viral vector delivers cardiac-specific and hypoxia-inducible VEGF expression in ischemic mouse hearts. Su, H., Joho, S., Huang, Y., Barcena, A., Arakawa-Hoyt, J., Grossman, W., Kan, Y.W. Proc. Natl. Acad. Sci. U.S.A. (2004)
- Fine-tuning in Ca2+ homeostasis underlies progression of cardiomyopathy in myocytes derived from genetically modified embryonic stem cells. Grey, C., Méry, A., Pucéat, M. Hum. Mol. Genet. (2005)
- Cardiac hypertrophy: signal transduction, transcriptional adaptation, and altered growth control. Wagner, M., Mascareno, E., Siddiqui, M.A. Ann. N. Y. Acad. Sci. (1999)
- Systematic analysis of the regulatory and essential myosin light chain genes: genetic variants and mutations in hypertrophic cardiomyopathy. Kabaeva, Z.T., Perrot, A., Wolter, B., Dietz, R., Cardim, N., Correia, J.M., Schulte, H.D., Aldashev, A.A., Mirrakhimov, M.M., Osterziel, K.J. Eur. J. Hum. Genet. (2002)
- Changes in essential myosin light chain isoform expression provide a molecular basis for isometric force regulation in the failing human heart. Morano, I., Hädicke, K., Haase, H., Böhm, M., Erdmann, E., Schaub, M.C. J. Mol. Cell. Cardiol. (1997)
- Genetically selected stem cells from human adipose tissue express cardiac markers. Bai, X., Pinkernell, K., Song, Y.H., Nabzdyk, C., Reiser, J., Alt, E. Biochem. Biophys. Res. Commun. (2007)
- Tissue-specific transcription of the cardiac myosin light-chain 2 gene is regulated by an upstream repressor element. Shen, R.A., Goswami, S.K., Mascareno, E., Kumar, A., Siddiqui, M.A. Mol. Cell. Biol. (1991)
- Key role of myosin light chain (MLC) kinase-mediated MLC2a phosphorylation in the alpha 1-adrenergic positive inotropic effect in human atrium. Grimm, M., Haas, P., Willipinski-Stapelfeldt, B., Zimmermann, W.H., Rau, T., Pantel, K., Weyand, M., Eschenhagen, T. Cardiovasc. Res. (2005)
- Elevated MHC class I and II antigens in cultured human embryonic myoblasts following stimulation with gamma-interferon. Bao, S.S., King, N.J., dos Remedios, C.G. Immunol. Cell Biol. (1990)
- A Proteomic Assessment of Muscle Contractile Alterations during Unloading and Reloading. Seo, Y., Lee, K., Park, K., Bae, K., Choi, I. J. Biochem. (2006)
- Dephosphorylation specificities of protein phosphatase for cardiac troponin I, troponin T, and sites within troponin T. Jideama, N.M., Crawford, B.H., Hussain, A.A., Raynor, R.L. Int. J. Biol. Sci. (2006)
- A new serum-responsive, cardiac tissue-specific transcription factor that recognizes the MEF-2 site in the myosin light chain-2 promoter. Zhou, M.D., Goswami, S.K., Martin, M.E., Siddiqui, M.A. Mol. Cell. Biol. (1993)
- Embryonic gene expression in nonoverloaded ventricles of hereditary hypertrophic cardiomyopathic hamsters. Di Nardo, P., Fiaccavento, R., Natali, A., Minieri, M., Sampaolesi, M., Fusco, A., Janmot, C., Cuda, G., Carbone, A., Rogliani, P., Peruzzi, G. Lab. Invest. (1997)
- Modulation of MLC-2v gene expression by AP-1: complex regulatory role of Jun in cardiac myocytes. Goswami, S.K., Shafiq, S., Siddiqui, M.A. Mol. Cell. Biochem. (2001)
- Dilated cardiomyopathy-associated proteins and their presentation in a WWW-accessible two-dimensional gel protein database. Pleissner, K.P., Söding, P., Sander, S., Oswald, H., Neuss, M., Regitz-Zagrosek, V., Fleck, E. Electrophoresis (1997)
- The human adult cardiomyocyte phenotype. Bird, S.D., Doevendans, P.A., van Rooijen, M.A., Brutel de la Riviere, A., Hassink, R.J., Passier, R., Mummery, C.L. Cardiovasc. Res. (2003)