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Gene Review

Aprt  -  Adenine phosphoribosyltransferase

Drosophila melanogaster

Synonyms: APRT, BcDNA:LP07986, CG18315, Dmel\CG18315, aprt
 
 
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High impact information on Aprt

 

Biological context of Aprt

  • Putative promoter sequences positioned upstream of the predicted transcriptional start site in the two Aprt genes have a similar structure of direct repeats with an overlapping dyad symmetry, but the DNA sequence of these motifs is not conserved between the two species [3].
  • Biological features in mutants of Aprt as well as natural variants suggest that dosage compensation of this gene in Drosophila pseudoobscura is due to a general control mechanism on X-linked genes rather than a gene-specific mechanism [3].
  • Nucleotide sequencing shows that four APRT cDNAs have a common 5' terminus with an apparent cap consensus sequence but two different 3' sites of polyadenylation [2].
 

Anatomical context of Aprt

 

Associations of Aprt with chemical compounds

References

 
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