Gene Review:
NPY5R - neuropeptide Y receptor Y5
Homo sapiens
Synonyms:
NPY-Y5 receptor, NPY5-R, NPYR5, NPYY5-R, Neuropeptide Y receptor type 5, ...
Ramanathan,
Woodroffe,
Flodman,
Mays,
Hanouni,
Modahl,
Steinberg-Epstein,
Bocian,
Spence,
Smith,
Gehlert,
Yang,
George,
Wang,
Schober,
Gackenheimer,
Johnson,
Beavers,
Gadski,
Baez,
Haynes,
Arch,
Wilson,
McClue,
Buckingham,
Kakui,
Tanaka,
Tabata,
Asai,
Masuda,
Miyara,
Nakatani,
Ohsawa,
Nishikawa,
Sugai,
Suzuki,
Aoki,
Kitaguchi,
Félétou,
Nicolas,
Rodriguez,
Beauverger,
Galizzi,
Boutin,
Duhault,
Qin,
Wang,
Fei,
Liu,
Cui,
Chen,
Jenkinson,
Cray,
Walder,
Herzog,
Hanson,
Ravussin,
- Novel polymorphisms in the neuropeptide-Y Y5 receptor associated with obesity in Pima Indians. Jenkinson, C.P., Cray, K., Walder, K., Herzog, H., Hanson, n.u.l.l., Ravussin, E. Int. J. Obes. Relat. Metab. Disord. (2000)
- Neuropeptide Y5 receptor antagonism does not induce clinically meaningful weight loss in overweight and obese adults. Erondu, N., Gantz, I., Musser, B., Suryawanshi, S., Mallick, M., Addy, C., Cote, J., Bray, G., Fujioka, K., Bays, H., Hollander, P., Sanabria-Boh??rquez, S.M., Eng, W., L??ngstr??m, B., Hargreaves, R.J., Burns, H.D., Kanatani, A., Fukami, T., Macneil, D.J., Gottesdiener, K.M., Amatruda, J.M., Kaufman, K.D., Heymsfield, S.B. Cell metabolism. (2006)
- Screening for mutations in the neuropeptide Y Y5 receptor gene in cohorts belonging to different weight extremes. Rosenkranz, K., Hinney, A., Ziegler, A., von Prittwitz, S., Barth, N., Roth, H., Mayer, H., Siegfried, W., Lehmkuhl, G., Poustka, F., Schmidt, M., Schäfer, H., Remschmidt, H., Hebebrand, J. Int. J. Obes. Relat. Metab. Disord. (1998)
- Treating obesity: Does antagonism of NPY fit the bill? Farooqi, S. Cell metabolism. (2006)
- Functional characterization of human neuropeptide Y receptor subtype five specific antagonists using a luciferase reporter gene assay. Beauverger, P., Rodriguez, M., Nicolas, J.P., Audinot, V., Lamamy, V., Dromaint, S., Nagel, N., Macia, C., Léopold, O., Galizzi, J.P., Caignard, D.H., Aldana, I., Monge, A., Chomarat, P., Boutin, J.A. Cell. Signal. (2005)
- The neuropeptide-Y Y5 receptor antagonist L-152,804 decreases alcohol self-administration in inbred alcohol-preferring (iP) rats. Schroeder, J.P., Overstreet, D.H., Hodge, C.W. Alcohol (2005)
- A receptor subtype involved in neuropeptide-Y-induced food intake. Gerald, C., Walker, M.W., Criscione, L., Gustafson, E.L., Batzl-Hartmann, C., Smith, K.E., Vaysse, P., Durkin, M.M., Laz, T.M., Linemeyer, D.L., Schaffhauser, A.O., Whitebread, S., Hofbauer, K.G., Taber, R.I., Branchek, T.A., Weinshank, R.L. Nature (1996)
- Emerging functions for neuropeptide Y5 receptors. Bischoff, A., Michel, M.C. Trends Pharmacol. Sci. (1999)
- Conservation of expression of neuropeptide Y5 receptor between human and rat hypothalamus and limbic regions suggests an integral role in central neuroendocrine control. Nichol, K.A., Morey, A., Couzens, M.H., Shine, J., Herzog, H., Cunningham, A.M. J. Neurosci. (1999)
- NPY regulates catecholamine secretion from human adrenal chromaffin cells. Cavadas, C., Silva, A.P., Mosimann, F., Cotrim, M.D., Ribeiro, C.A., Brunner, H.R., Grouzmann, E. J. Clin. Endocrinol. Metab. (2001)
- Overlapping gene structure of the human neuropeptide Y receptor subtypes Y1 and Y5 suggests coordinate transcriptional regulation. Herzog, H., Darby, K., Ball, H., Hort, Y., Beck-Sickinger, A., Shine, J. Genomics (1997)
- Subtype selectivity of the novel nonpeptide neuropeptide Y Y1 receptor antagonist BIBO 3304 and its effect on feeding in rodents. Wieland, H.A., Engel, W., Eberlein, W., Rudolf, K., Doods, H.N. Br. J. Pharmacol. (1998)
- Cloning and characterization of Rhesus monkey neuropeptide Y receptor subtypes. Gehlert, D.R., Yang, P., George, C., Wang, Y., Schober, D., Gackenheimer, S., Johnson, D., Beavers, L.S., Gadski, R.A., Baez, M. Peptides (2001)
- NPY receptor subtype in the rabbit isolated ileum. Félétou, M., Nicolas, J.P., Rodriguez, M., Beauverger, P., Galizzi, J.P., Boutin, J.A., Duhault, J. Br. J. Pharmacol. (1999)
- Evidence for involvement of neuropeptide Y receptors in the regulation of food intake: studies with Y1-selective antagonist BIBP3226. Kask, A., Rägo, L., Harro, J. Br. J. Pharmacol. (1998)
- Discrete distribution of the neuropeptide Y Y5 receptor gene in the human brain: an in situ hybridization study. Jacques, D., Tong, Y., Shen, S.H., Quirion, R. Brain Res. Mol. Brain Res. (1998)
- Novel potent antagonists of human neuropeptide Y Y5 receptors. Part 2: substituted benzo[a]cycloheptene derivatives. Itani, H., Ito, H., Sakata, Y., Hatakeyama, Y., Oohashi, H., Satoh, Y. Bioorg. Med. Chem. Lett. (2002)
- Neuropeptide Y lowers blood glucose in anaesthetized rats via a Y5 receptor subtype. Bischoff, A., Michel, M.C. Endocrinology (1998)
- Pharmacological Characterization and Feeding-Suppressive Property of FMS586 [3-(5,6,7,8-Tetrahydro-9-isopropyl-carbazol-3-yl)-1-methyl-1-(2-pyridin-4-yl-ethyl)-urea Hydrochloride], a Novel, Selective, and Orally Active Antagonist for Neuropeptide Y Y5 Receptor. Kakui, N., Tanaka, J., Tabata, Y., Asai, K., Masuda, N., Miyara, T., Nakatani, Y., Ohsawa, F., Nishikawa, N., Sugai, M., Suzuki, M., Aoki, K., Kitaguchi, H. J. Pharmacol. Exp. Ther. (2006)
- From transcription profile to expression: the signaling repertoire of the SK-N-MC neuroepithelioma cell-line. Bader, J.E., Deckert, C.M., Koglin, N., Pluder, F., Mörl, K., Koczan, D., Thiesen, H.J., Beck-Sickinger, A.G. J. Recept. Signal Transduct. Res. (2004)
- Neuropeptide Y induces migration, proliferation, and tube formation of endothelial cells bimodally via Y1, Y2, and Y5 receptors. Movafagh, S., Hobson, J.P., Spiegel, S., Kleinman, H.K., Zukowska, Z. FASEB J. (2006)
- A case of autism with an interstitial deletion on 4q leading to hemizygosity for genes encoding for glutamine and glycine neurotransmitter receptor sub-units (AMPA 2, GLRA3, GLRB) and neuropeptide receptors NPY1R, NPY5R. Ramanathan, S., Woodroffe, A., Flodman, P.L., Mays, L.Z., Hanouni, M., Modahl, C.B., Steinberg-Epstein, R., Bocian, M.E., Spence, M.A., Smith, M. BMC Med. Genet. (2004)
- Characterisation of the neuropeptide Y receptor that mediates feeding in the rat: a role for the Y5 receptor? Haynes, A.C., Arch, J.R., Wilson, S., McClue, S., Buckingham, R.E. Regul. Pept. (1998)
- Comparison of Y-receptor subtype expression in the rat hippocampus. Parker, R.M., Herzog, H. Regul. Pept. (1998)
- Involvement of dopamine D3 and neuropeptide Y Y5 receptors in diabetic gastroparetic rats without response to erythromycin. Qin, X.Y., Wang, Z.G., Fei, J., Liu, F.L., Cui, D.F., Chen, S.L. Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (2003)
- Attenuation of circadian light induced phase advances and delays by neuropeptide Y and a neuropeptide Y Y1/Y5 receptor agonist. Lall, G.S., Biello, S.M. Neuroscience (2003)
- Blockade of the NPY Y5 receptor potentiates circadian responses to light: complementary in vivo and in vitro studies. Yannielli, P.C., Brewer, J.M., Harrington, M.E. Eur. J. Neurosci. (2004)