Gene Review:
ROR2 - receptor tyrosine kinase-like orphan...
Homo sapiens
Synonyms:
BDB, BDB1, NTRKR2, Neurotrophic tyrosine kinase, receptor-related 2, Tyrosine-protein kinase transmembrane receptor ROR2
- Comparative genomics on ROR1 and ROR2 orthologs. Katoh, M., Katoh, M. Oncol. Rep. (2005)
- Interstitial deletion of chromosome 9, int del(9)(9q22.31-q31.2), including the genes causing multiple basal cell nevus syndrome and Robinow/brachydactyly 1 syndrome. Olivieri, C., Maraschio, P., Caselli, D., Martini, C., Beluffi, G., Maserati, E., Danesino, C. Eur. J. Pediatr. (2003)
- One gene, two phenotypes: ROR2 mutations in autosomal recessive Robinow syndrome and autosomal dominant brachydactyly type B. Afzal, A.R., Jeffery, S. Hum. Mutat. (2003)
- The orphan receptor tyrosine kinase Ror2 promotes osteoblast differentiation and enhances ex vivo bone formation. Liu, Y., Bhat, R.A., Seestaller-Wehr, L.M., Fukayama, S., Mangine, A., Moran, R.A., Komm, B.S., Bodine, P.V., Billiard, J. Mol. Endocrinol. (2007)
- Dominant mutations in ROR2, encoding an orphan receptor tyrosine kinase, cause brachydactyly type B. Oldridge, M., Fortuna, A.M., Maringa, M., Propping, P., Mansour, S., Pollitt, C., DeChiara, T.M., Kimble, R.B., Valenzuela, D.M., Yancopoulos, G.D., Wilkie, A.O. Nat. Genet. (2000)
- Recessive Robinow syndrome, allelic to dominant brachydactyly type B, is caused by mutation of ROR2. Afzal, A.R., Rajab, A., Fenske, C.D., Oldridge, M., Elanko, N., Ternes-Pereira, E., Tüysüz, B., Murday, V.A., Patton, M.A., Wilkie, A.O., Jeffery, S. Nat. Genet. (2000)
- Mutation of the gene encoding the ROR2 tyrosine kinase causes autosomal recessive Robinow syndrome. van Bokhoven, H., Celli, J., Kayserili, H., van Beusekom, E., Balci, S., Brussel, W., Skovby, F., Kerr, B., Percin, E.F., Akarsu, N., Brunner, H.G. Nat. Genet. (2000)
- Robinow syndrome. Patton, M.A., Afzal, A.R. J. Med. Genet. (2002)
- ER-associated protein degradation is a common mechanism underpinning numerous monogenic diseases including Robinow syndrome. Chen, Y., Bellamy, W.P., Seabra, M.C., Field, M.C., Ali, B.R. Hum. Mol. Genet. (2005)
- Identification of protein kinases dysregulated in CD4(+) T cells in pathogenic versus apathogenic simian immunodeficiency virus infection. Bostik, P., Wu, P., Dodd, G.L., Villinger, F., Mayne, A.E., Bostik, V., Grimm, B.D., Robinson, D., Kung, H.J., Ansari, A.A. J. Virol. (2001)
- Genetic linkage of human height is confirmed to 9q22 and Xq24. Liu, Y.Z., Xiao, P., Guo, Y.F., Xiong, D.H., Zhao, L.J., Shen, H., Liu, Y.J., Dvornyk, V., Long, J.R., Deng, H.Y., Li, J.L., Recker, R.R., Deng, H.W. Hum. Genet. (2006)
- The receptor tyrosine kinase Ror2 associates with the melanoma-associated antigen (MAGE) family protein Dlxin-1 and regulates its intracellular distribution. Matsuda, T., Suzuki, H., Oishi, I., Kani, S., Kuroda, Y., Komori, T., Sasaki, A., Watanabe, K., Minami, Y. J. Biol. Chem. (2003)
- A novel family of cell surface receptors with tyrosine kinase-like domain. Masiakowski, P., Carroll, R.D. J. Biol. Chem. (1992)
- Screening for and validated quantification of amphetamines and of amphetamine- and piperazine-derived designer drugs in human blood plasma by gas chromatography/mass spectrometry. Peters, F.T., Schaefer, S., Staack, R.F., Kraemer, T., Maurer, H.H. Journal of mass spectrometry : JMS. (2003)
- Recent methods for assessing effectiveness of antihypertensive agents. Schneider, B.E., Littman, G.S., Walker, B.R. Clinical therapeutics. (1983)
- A behavioral comparison of Nexus, cathinone, BDB, and MDA. Bronson, M.E., Jiang, W., DeRuiter, J., Clark, C.R. Pharmacol. Biochem. Behav. (1995)
- Multiplex assay of amphetamine, methamphetamine, and ecstasy drug using CEDIA technology. Loor, R., Lingenfelter, C., Wason, P.P., Tang, K., Davoudzadeh, D. Journal of analytical toxicology. (2002)
- Homodimerization of Ror2 tyrosine kinase receptor induces 14-3-3(beta) phosphorylation and promotes osteoblast differentiation and bone formation. Liu, Y., Ross, J.F., Bodine, P.V., Billiard, J. Mol. Endocrinol. (2007)
- Distinct mutations in the receptor tyrosine kinase gene ROR2 cause brachydactyly type B. Schwabe, G.C., Tinschert, S., Buschow, C., Meinecke, P., Wolff, G., Gillessen-Kaesbach, G., Oldridge, M., Wilkie, A.O., Kömec, R., Mundlos, S. Am. J. Hum. Genet. (2000)
- A Thai mother and son with distal symphalangism, hypoplastic carpal bones, microdontia, dental pulp stones, and narrowing of the zygomatic arch: a new distal symphalangism syndrome? Kantaputra, P.N., Kinoshita, A., Limwonges, C., Praditsup, O., Niikawa, N. Am. J. Med. Genet. (2002)
- Excretion of MBDB and BDB in urine, saliva, and sweat following single oral administration. Kintz, P. Journal of analytical toxicology. (1997)