Gene Review:
CD207 - CD207 molecule, langerin
Homo sapiens
Synonyms:
C-type lectin domain family 4 member K, CLEC4K, Langerin
Geissmann,
Lepelletier,
Fraitag,
Valladeau,
Bodemer,
Debré,
Leborgne,
Saeland,
Brousse,
Larregina,
Morelli,
Spencer,
Logar,
Watkins,
Thomson,
Falo,
Smetana,
Mericka,
Saeland,
Homolka,
Brabec,
Gabius,
Valladeau,
Dezutter-Dambuyant,
Saeland,
Tirlapur,
Mulholland,
Bellhouse,
Kendall,
Cornhill,
Cui,
Patterson,
Donaghy,
Amjadi,
Gazzard,
Gotch,
Kelleher,
Bousarghin,
Hubert,
Franzen,
Jacobs,
Boniver,
Delvenne,
- Langerhans cells utilize CD1a and langerin to efficiently present nonpeptide antigens to T cells. Hunger, R.E., Sieling, P.A., Ochoa, M.T., Sugaya, M., Burdick, A.E., Rea, T.H., Brennan, P.J., Belisle, J.T., Blauvelt, A., Porcelli, S.A., Modlin, R.L. J. Clin. Invest. (2004)
- Human papillomavirus 16 virus-like particles use heparan sulfates to bind dendritic cells and colocalize with langerin in Langerhans cells. Bousarghin, L., Hubert, P., Franzen, E., Jacobs, N., Boniver, J., Delvenne, P. J. Gen. Virol. (2005)
- Comparison of the expression of Langerin and 175 kD mannose receptor in antigen-presenting cells in normal human skin and basal cell carcinoma. Plzáková, Z., Chovanec, M., Smetana, K., Plzák, J., Stork, J., Saeland, S. Folia Biol. (Praha) (2004)
- Langerin, a novel C-type lectin specific to Langerhans cells, is an endocytic receptor that induces the formation of Birbeck granules. Valladeau, J., Ravel, O., Dezutter-Dambuyant, C., Moore, K., Kleijmeer, M., Liu, Y., Duvert-Frances, V., Vincent, C., Schmitt, D., Davoust, J., Caux, C., Lebecque, S., Saeland, S. Immunity (2000)
- Dermal-resident CD14+ cells differentiate into Langerhans cells. Larregina, A.T., Morelli, A.E., Spencer, L.A., Logar, A.J., Watkins, S.C., Thomson, A.W., Falo, L.D. Nat. Immunol. (2001)
- Fetal and neonatal murine skin harbors Langerhans cell precursors. Chang-Rodriguez, S., Hoetzenecker, W., Schwärzler, C., Biedermann, T., Saeland, S., Elbe-Bürger, A. J. Leukoc. Biol. (2005)
- Large-scale isolation of immature dendritic cells with features of Langerhans cells by sorting CD34+ cord blood stem cells cultured in the presence of TGF-beta1 for cutaneous leukocyte antigen (CLA). Bartz, H., Rothoeft, T., Anhenn, O., Bunse, D., Schauer, U. J. Immunol. Methods (2003)
- A lack of Birbeck granules in Langerhans cells is associated with a naturally occurring point mutation in the human Langerin gene. Verdijk, P., Dijkman, R., Plasmeijer, E.I., Mulder, A.A., Zoutman, W.H., Mieke Mommaas, A., Tensen, C.P. J. Invest. Dermatol. (2005)
- Polymorphisms in human langerin affect stability and sugar binding activity. Ward, E.M., Stambach, N.S., Drickamer, K., Taylor, M.E. J. Biol. Chem. (2006)
- Langerin/CD207 sheds light on formation of birbeck granules and their possible function in Langerhans cells. Valladeau, J., Dezutter-Dambuyant, C., Saeland, S. Immunol. Res. (2003)
- Langerin (CD207) staining in normal pediatric tissues, reactive lymph nodes, and childhood histiocytic disorders. Chikwava, K., Jaffe, R. Pediatr. Dev. Pathol. (2004)
- The role of dendritic cell C-type lectin receptors in HIV pathogenesis. Turville, S., Wilkinson, J., Cameron, P., Dable, J., Cunningham, A.L. J. Leukoc. Biol. (2003)
- Identification and characterization of endogenous Langerin ligands in murine extracellular matrix. Tada, Y., Riedl, E., Lowenthal, M.S., Liotta, L.A., Briner, D.M., Crouch, E.C., Udey, M.C. J. Invest. Dermatol. (2006)
- Characterization of carbohydrate recognition by langerin, a C-type lectin of Langerhans cells. Stambach, N.S., Taylor, M.E. Glycobiology (2003)
- Despite differences between dendritic cells and Langerhans cells in the mechanism of papillomavirus-like particle antigen uptake, both cells cross-prime T cells. Yan, M., Peng, J., Jabbar, I.A., Liu, X., Filgueira, L., Frazer, I.H., Thomas, R. Virology (2004)
- Carbohydrate microarrays reveal sulphation as a modulator of siglec binding. Campanero-Rhodes, M.A., Childs, R.A., Kiso, M., Komba, S., Le Narvor, C., Warren, J., Otto, D., Crocker, P.R., Feizi, T. Biochem. Biophys. Res. Commun. (2006)
- Antagonistic effects of IL-4 and TGF-beta1 on Langerhans cell-related antigen expression by human monocytes. Guironnet, G., Dezutter-Dambuyant, C., Vincent, C., Bechetoille, N., Schmitt, D., Péguet-Navarro, J. J. Leukoc. Biol. (2002)
- Differentiation of Langerhans cells in Langerhans cell histiocytosis. Geissmann, F., Lepelletier, Y., Fraitag, S., Valladeau, J., Bodemer, C., Debré, M., Leborgne, M., Saeland, S., Brousse, N. Blood (2001)
- Human BDCA-1-positive blood dendritic cells differentiate into phenotypically distinct immature and mature populations in the absence of exogenous maturational stimuli: differentiation failure in HIV infection. Patterson, S., Donaghy, H., Amjadi, P., Gazzard, B., Gotch, F., Kelleher, P. J. Immunol. (2005)
- Interleukin-3 in cooperation with transforming growth factor beta induces granulocyte macrophage colony stimulating factor independent differentiation of human CD34+ hematopoietic progenitor cells into dendritic cells with features of Langerhans cells. Mollah, Z.U., Aiba, S., Nakagawa, S., Mizuashi, M., Ohtani, T., Yoshino, Y., Tagami, H. J. Invest. Dermatol. (2003)
- Femtosecond two-photon high-resolution 3D imaging, spatial-volume rendering and microspectral characterization of immunolocalized MHC-II and mLangerin/CD207 antigens in the mouse epidermis. Tirlapur, U.K., Mulholland, W.J., Bellhouse, B.J., Kendall, M., Cornhill, J.F., Cui, Z. Microsc. Res. Tech. (2006)
- Diagnostic relevance of Langerin detection in cells from bronchoalveolar lavage of patients with pulmonary Langerhans cell histiocytosis, sarcoidosis and idiopathic pulmonary fibrosis. Smetana, K., Mericka, O., Saeland, S., Homolka, J., Brabec, J., Gabius, H.J. Virchows Arch. (2004)