Gene Review:
SERPINB5 - serpin peptidase inhibitor, clade B...
Homo sapiens
Synonyms:
Maspin, PI-5, PI5, Peptidase inhibitor 5, Serpin B5, ...
- Maspin mediates increased tumor cell apoptosis upon induction of the mitochondrial permeability transition. Latha, K., Zhang, W., Cella, N., Shi, H.Y., Zhang, M. Mol. Cell. Biol. (2005)
- Maspin expression is transactivated by p63 and is critical for the modulation of lung cancer progression. Kim, S., Han, J., Kim, J., Park, C. Cancer Res. (2004)
- Tumor-suppressive maspin regulates cell response to oxidative stress by direct interaction with glutathione S-transferase. Yin, S., Li, X., Meng, Y., Finley, R.L., Sakr, W., Yang, H., Reddy, N., Sheng, S. J. Biol. Chem. (2005)
- Role for DNA methylation in the control of cell type specific maspin expression. Futscher, B.W., Oshiro, M.M., Wozniak, R.J., Holtan, N., Hanigan, C.L., Duan, H., Domann, F.E. Nat. Genet. (2002)
- Maspin, a serpin with tumor-suppressing activity in human mammary epithelial cells. Zou, Z., Anisowicz, A., Hendrix, M.J., Thor, A., Neveu, M., Sheng, S., Rafidi, K., Seftor, E., Sager, R. Science (1994)
- Maspin sensitizes prostate cancer cells to doxazosin-induced apoptosis. Tahmatzopoulos, A., Sheng, S., Kyprianou, N. Oncogene (2005)
- Prognostic value of maspin mRNA expression in ER alpha-positive postmenopausal breast carcinomas. Bièche, I., Girault, I., Sabourin, J.C., Tozlu, S., Driouch, K., Vidaud, M., Lidereau, R. Br. J. Cancer (2003)
- Expression and regulation of tumor suppressor gene maspin in breast cancer. Maass, N., Nagasaki, K., Ziebart, M., Mundhenke, C., Jonat, W. Clin. Breast Cancer (2002)
- Epigenetic regulation of maspin expression in human ovarian carcinoma cells. Rose, S.L., Fitzgerald, M.P., White, N.O., Hitchler, M.J., Futscher, B.W., De Geest, K., Domann, F.E. Gynecol. Oncol. (2006)
- Mammary serine protease inhibitor (Maspin) binds directly to interferon regulatory factor 6: identification of a novel serpin partnership. Bailey, C.M., Khalkhali-Ellis, Z., Kondo, S., Margaryan, N.V., Seftor, R.E., Wheaton, W.W., Amir, S., Pins, M.R., Schutte, B.C., Hendrix, M.J. J. Biol. Chem. (2005)
- Pleiotrophic inhibition of pericellular urokinase-type plasminogen activator system by endogenous tumor suppressive maspin. Biliran, H., Sheng, S. Cancer Res. (2001)
- Maspin in thyroid cancer: its relationship with p53 and clinical outcome. Boltze, C., Schneider-Stock, R., Meyer, F., Peters, B., Quednow, C., Hoang-Vu, C., Roessner, A. Oncol. Rep. (2003)
- Loss of maspin expression is associated with development and progression of gastric carcinoma with p53 abnormality. Ito, R., Nakayama, H., Yoshida, K., Oda, N., Yasui, W. Oncol. Rep. (2004)
- Tamoxifen induces the expression of maspin through estrogen receptor-alpha. Liu, Z., Shi, H.Y., Nawaz, Z., Zhang, M. Cancer Lett. (2004)
- Maspin retards cell detachment via a novel interaction with the urokinase-type plasminogen activator/urokinase-type plasminogen activator receptor system. Yin, S., Lockett, J., Meng, Y., Biliran, H., Blouse, G.E., Li, X., Reddy, N., Zhao, Z., Lin, X., Anagli, J., Cher, M.L., Sheng, S. Cancer Res. (2006)
- TAp63gamma can substitute for p53 in inducing expression of the maspin tumor suppressor. Spiesbach, K., Tannapfel, A., Mössner, J., Engeland, K. Int. J. Cancer (2005)
- The surface of prostate carcinoma DU145 cells mediates the inhibition of urokinase-type plasminogen activator by maspin. McGowen, R., Biliran, H., Sager, R., Sheng, S. Cancer Res. (2000)
- Pathobiological significance of vascular endothelial growth factor and Maspin expressions in human gastric carcinoma. Li, J.J., Chen, Y., Zhang, S.M., Wu, D.Y., Wang, Y.P., Xin, Y. World J. Gastroenterol. (2004)