Gene Review:
PIK3R2 - phosphoinositide-3-kinase, regulatory...
Homo sapiens
Synonyms:
MPPH, MPPH1, P85B, PI3-kinase regulatory subunit beta, PI3-kinase subunit p85-beta, ...
- Expression and characterization of the p85 subunit of the phosphatidylinositol 3-kinase complex and a related p85 beta protein by using the baculovirus expression system. Gout, I., Dhand, R., Panayotou, G., Fry, M.J., Hiles, I., Otsu, M., Waterfield, M.D. Biochem. J. (1992)
- Characterization of two 85 kd proteins that associate with receptor tyrosine kinases, middle-T/pp60c-src complexes, and PI3-kinase. Otsu, M., Hiles, I., Gout, I., Fry, M.J., Ruiz-Larrea, F., Panayotou, G., Thompson, A., Dhand, R., Hsuan, J., Totty, N. Cell (1991)
- Regulation by insulin of phosphatidylinositol 3'-kinase bound to alpha- and beta-isoforms of p85 regulatory subunit. Baltensperger, K., Kozma, L.M., Jaspers, S.R., Czech, M.P. J. Biol. Chem. (1994)
- Divergent regulation of phosphatidylinositol 3-kinase P85 alpha and P85 beta isoforms upon T cell activation. Reif, K., Gout, I., Waterfield, M.D., Cantrell, D.A. J. Biol. Chem. (1993)
- Chromosomal localization of human p85 alpha, a subunit of phosphatidylinositol 3-kinase, and its homologue p85 beta. Volinia, S., Patracchini, P., Otsu, M., Hiles, I., Gout, I., Calzolari, E., Bernardi, F., Rooke, L., Waterfield, M.D. Oncogene (1992)
- Diversification of cardiac insulin signaling involves the p85 alpha/beta subunits of phosphatidylinositol 3-kinase. Kessler, A., Uphues, I., Ouwens, D.M., Till, M., Eckel, J. Am. J. Physiol. Endocrinol. Metab. (2001)
- Insulin-like growth factor-I stimulates Shc-dependent phosphatidylinositol 3-kinase activation via Grb2-associated p85 in vascular smooth muscle cells. Radhakrishnan, Y., Maile, L.A., Ling, Y., Graves, L.M., Clemmons, D.R. J. Biol. Chem. (2008)