Gene Review:
PLIN1 - perilipin 1
Homo sapiens
Synonyms:
FPLD4, Lipid droplet-associated protein, PERI, PLIN, Perilipin-1
- Obese subjects carrying the 11482G>A polymorphism at the perilipin locus are resistant to weight loss after dietary energy restriction. Corella, D., Qi, L., Sorlí, J.V., Godoy, D., Portolés, O., Coltell, O., Greenberg, A.S., Ordovas, J.M. J. Clin. Endocrinol. Metab. (2005)
- Polymorphisms in PLIN and hypertension combined with obesity and lipid profiles in Han Chinese. Yan, W., Chen, S., Huang, J., Shen, Y., Qiang, B., Gu, D. Obes. Res. (2004)
- Genetic variation at the perilipin (PLIN) locus is associated with obesity-related phenotypes in White women. Qi, L., Corella, D., Sorlí, J.V., Portolés, O., Shen, H., Coltell, O., Godoy, D., Greenberg, A.S., Ordovas, J.M. Clin. Genet. (2004)
- Genes of cholesterol metabolism in human atheroma: overexpression of perilipin and genes promoting cholesterol storage and repression of ABCA1 expression. Forcheron, F., Legedz, L., Chinetti, G., Feugier, P., Letexier, D., Bricca, G., Beylot, M. Arterioscler. Thromb. Vasc. Biol. (2005)
- Rett syndrome: case reports and management strategies. Burd, L., Gascon, G., Kerbeshian, J. Neuroscience and biobehavioral reviews. (1988)
- Peri-sleep-onset cortisol levels in children and adolescents with affective disorders. Forbes, E.E., Williamson, D.E., Ryan, N.D., Birmaher, B., Axelson, D.A., Dahl, R.E. Biol. Psychiatry (2006)
- Predictors of chronic post-traumatic stress disorder. A prospective study. Freedman, S.A., Brandes, D., Peri, T., Shalev, A. The British journal of psychiatry : the journal of mental science. (1999)
- Post-partum depression and the mother-infant relationship in a South African peri-urban settlement. Cooper, P.J., Tomlinson, M., Swartz, L., Woolgar, M., Murray, L., Molteno, C. The British journal of psychiatry : the journal of mental science. (1999)
- Suppression of aggregate formation and apoptosis by transglutaminase inhibitors in cells expressing truncated DRPLA protein with an expanded polyglutamine stretch. Igarashi, S., Koide, R., Shimohata, T., Yamada, M., Hayashi, Y., Takano, H., Date, H., Oyake, M., Sato, T., Sato, A., Egawa, S., Ikeuchi, T., Tanaka, H., Nakano, R., Tanaka, K., Hozumi, I., Inuzuka, T., Takahashi, H., Tsuji, S. Nat. Genet. (1998)
- Down-regulation of plasminogen activator inhibitor 1 expression promotes myocardial neovascularization by bone marrow progenitors. Xiang, G., Schuster, M.D., Seki, T., Kocher, A.A., Eshghi, S., Boyle, A., Itescu, S. J. Exp. Med. (2004)
- Sex steroids, bone mass, and bone loss. A prospective study of pre-, peri-, and postmenopausal women. Slemenda, C., Longcope, C., Peacock, M., Hui, S., Johnston, C.C. J. Clin. Invest. (1996)
- Full-thickness biopsy of the jejunum reveals inflammation and enteric neuropathy in irritable bowel syndrome. Törnblom, H., Lindberg, G., Nyberg, B., Veress, B. Gastroenterology (2002)
- Endosonography-guided fine-needle aspiration biopsy: diagnostic accuracy and complication assessment. Wiersema, M.J., Vilmann, P., Giovannini, M., Chang, K.J., Wiersema, L.M. Gastroenterology (1997)
- Evidence for an important role of perilipin in the regulation of human adipocyte lipolysis. Mottagui-Tabar, S., Rydén, M., Löfgren, P., Faulds, G., Hoffstedt, J., Brookes, A.J., Andersson, I., Arner, P. Diabetologia (2003)
- The 11482G >A polymorphism in the perilipin gene is associated with weight gain with rosiglitazone treatment in type 2 diabetes. Kang, E.S., Cha, B.S., Kim, H.J., Kim, H.J., Kim, S.H., Hur, K.Y., Lee, H.J., Shim, W.S., Ahn, C.W., Lee, H.C. Diabetes Care (2006)
- Effects of Aralia mandshurica and Engelhardtia chrysolepis extracts on some parameters of lipid metabolism in women with nondiabetic obesity. Abidov, M.T., del Rio, M.J., Ramazanov, T.Z., Klimenov, A.L., Dzhamirze, S.h., Kalyuzhin, O.V. Bull. Exp. Biol. Med. (2006)
- The dobutamine stress test with thallium-201 single-photon emission computed tomography and radionuclide angiography: postinfarction study. Coma-Canella, I., Gómez Martínez, M.V., Rodrigo, F., Castro Beiras, J.M. J. Am. Coll. Cardiol. (1993)
- Intragenic linkage disequilibrium structure of the human perilipin gene (PLIN) and haplotype association with increased obesity risk in a multiethnic Asian population. Qi, L., Tai, E.S., Tan, C.E., Shen, H., Chew, S.K., Greenberg, A.S., Corella, D., Ordovas, J.M. J. Mol. Med. (2005)
- Perilipin targets a novel pool of lipid droplets for lipolytic attack by hormone-sensitive lipase. Moore, H.P., Silver, R.B., Mottillo, E.P., Bernlohr, D.A., Granneman, J.G. J. Biol. Chem. (2005)
- Perilipin expression in human adipose tissue is elevated with obesity. Kern, P.A., Di Gregorio, G., Lu, T., Rassouli, N., Ranganathan, G. J. Clin. Endocrinol. Metab. (2004)
- Effects of the human immunodeficiency virus-protease inhibitor, ritonavir, on basal and catecholamine-stimulated lipolysis. Adler-Wailes, D.C., Liu, H., Ahmad, F., Feng, N., Londos, C., Manganiello, V., Yanovski, J.A. J. Clin. Endocrinol. Metab. (2005)
- Effect of testosterone on lipolysis in human pre-adipocytes from different fat depots. Dicker, A., Rydén, M., Näslund, E., Muehlen, I.E., Wirén, M., Lafontan, M., Arner, P. Diabetologia (2004)
- Targets for TNF-alpha-induced lipolysis in human adipocytes. Rydén, M., Arvidsson, E., Blomqvist, L., Perbeck, L., Dicker, A., Arner, P. Biochem. Biophys. Res. Commun. (2004)
- Involvement of a cGMP-dependent pathway in the natriuretic peptide-mediated hormone-sensitive lipase phosphorylation in human adipocytes. Sengenes, C., Bouloumie, A., Hauner, H., Berlan, M., Busse, R., Lafontan, M., Galitzky, J. J. Biol. Chem. (2003)
- Eukaryotic lipid body proteins in oleogenous actinomycetes and their targeting to intracellular triacylglycerol inclusions: impact on models of lipid body biogenesis. H??nisch, J., W??ltermann, M., Robenek, H., Steinb??chel, A. Appl. Environ. Microbiol. (2006)
- Isolation and chromosomal mapping of the human homolog of perilipin (PLIN), a rat adipose tissue-specific gene, by differential display method. Nishiu, J., Tanaka, T., Nakamura, Y. Genomics (1998)
- Functional Compensation for Adipose Differentiation-related Protein (ADFP) by Tip47 in an ADFP Null Embryonic Cell Line. Sztalryd, C., Bell, M., Lu, X., Mertz, P., Hickenbottom, S., Chang, B.H., Chan, L., Kimmel, A.R., Londos, C. J. Biol. Chem. (2006)