Gene Review:
EXOSC10 - exosome component 10
Homo sapiens
Synonyms:
Autoantigen PM/Scl 2, Exosome component 10, P100 polymyositis-scleroderma overlap syndrome-associated autoantigen, PM-Scl, PM/Scl-100, ...
- Molecular characterization of an autoantigen of PM-Scl in the polymyositis/scleroderma overlap syndrome: a unique and complete human cDNA encoding an apparent 75-kD acidic protein of the nucleolar complex. Alderuccio, F., Chan, E.K., Tan, E.M. J. Exp. Med. (1991)
- IgE reactivity pattern to timothy and birch pollen allergens in Finnish and Russian Karelia. Movérare, R., Petays, T., Vartiainen, E., Haahtela, T. Int. Arch. Allergy Immunol. (2005)
- Mechanism of inhibition of the retroviral protease by a Rous sarcoma virus peptide substrate representing the cleavage site between the gag p2 and p10 proteins. Cameron, C.E., Grinde, B., Jentoft, J., Leis, J., Weber, I.T., Copeland, T.D., Wlodawer, A. J. Biol. Chem. (1992)
- Abeta 17-42 in Alzheimer's disease activates JNK and caspase-8 leading to neuronal apoptosis. Wei, W., Norton, D.D., Wang, X., Kusiak, J.W. Brain (2002)
- Crystal structure of peach Pru p 3, the prototypic member of the family of plant non-specific lipid transfer protein pan-allergens. Pasquato, N., Berni, R., Folli, C., Folloni, S., Cianci, M., Pantano, S., Helliwell, J.R., Zanotti, G. J. Mol. Biol. (2006)
- The yeast exosome and human PM-Scl are related complexes of 3' --> 5' exonucleases. Allmang, C., Petfalski, E., Podtelejnikov, A., Mann, M., Tollervey, D., Mitchell, P. Genes Dev. (1999)
- Processing of 3'-extended read-through transcripts by the exosome can generate functional mRNAs. Torchet, C., Bousquet-Antonelli, C., Milligan, L., Thompson, E., Kufel, J., Tollervey, D. Mol. Cell (2002)
- Cloning of a complementary DNA coding for the 100-kD antigenic protein of the PM-Scl autoantigen. Ge, Q., Frank, M.B., O'Brien, C., Targoff, I.N. J. Clin. Invest. (1992)
- A segmental gene duplication generated differentially expressed myb-homologous genes in maize. Zhang, P., Chopra, S., Peterson, T. Plant Cell (2000)
- The global regulators GacA and sigma(S) form part of a cascade that controls alginate production in Azotobacter vinelandii. Castañeda, M., Sánchez, J., Moreno, S., Núñez, C., Espín, G. J. Bacteriol. (2001)
- Assembly of multimeric phage nanostructures through leucine zipper interactions. Sweeney, R.Y., Park, E.Y., Iverson, B.L., Georgiou, G. Biotechnol. Bioeng. (2006)
- Molecular characterization of the group 4 house dust mite allergen from Dermatophagoides pteronyssinus and its amylase homologue from Euroglyphus maynei. Mills, K.L., Hart, B.J., Lynch, N.R., Thomas, W.R., Smith, W. Int. Arch. Allergy Immunol. (1999)
- Immunologic aspects of scleroderma. Needleman, B.W. Current opinion in rheumatology. (1992)
- Structure and localization of mouse Pmscl1 and Pmscl2 genes. Bliskovski, V., Liddell, R., Ramsay, E.S., Miller, M.J., Mock, B.A. Genomics (2000)
- Nuclear mRNA degradation pathway(s) are implicated in Xist regulation and X chromosome inactivation. Ciaudo, C., Bourdet, A., Cohen-Tannoudji, M., Dietz, H.C., Rougeulle, C., Avner, P. PLoS Genet. (2006)
- Rrp47p is an exosome-associated protein required for the 3' processing of stable RNAs. Mitchell, P., Petfalski, E., Houalla, R., Podtelejnikov, A., Mann, M., Tollervey, D. Mol. Cell. Biol. (2003)
- Serum autoantibody to the nucleolar antigen PM-Scl. Clinical and immunogenetic associations. Oddis, C.V., Okano, Y., Rudert, W.A., Trucco, M., Duquesnoy, R.J., Medsger, T.A. Arthritis Rheum. (1992)
- Response of a human T cell clone to a large panel of altered peptide ligands carrying single residue substitutions in an antigenic peptide: characterization and frequencies of TCR agonism and TCR antagonism with or without partial activation. Chen, Y.Z., Matsushita, S., Nishimura, Y. J. Immunol. (1996)
- Pancreatic-polypeptide in the human pancreas: expression and quantitative variation during development and in ductal adenocarcinoma. Tamiolakis, D., Simopoulos, C., Kotini, A., Venizelos, I., Jivannakis, T., Papadopoulos, N. Acta medica (Hradec Králové) / Universitas Carolina, Facultas Medica Hradec Králové. (2003)
- Amyloidogenic processing of the human amyloid precursor protein in primary cultures of rat hippocampal neurons. Simons, M., de Strooper, B., Multhaup, G., Tienari, P.J., Dotti, C.G., Beyreuther, K. J. Neurosci. (1996)
- Interaction of mite allergens Der p3 and Der p9 with protease-activated receptor-2 expressed by lung epithelial cells. Sun, G., Stacey, M.A., Schmidt, M., Mori, L., Mattoli, S. J. Immunol. (2001)
- Identification and HLA restriction of naturally derived Th1-cell epitopes from the secreted Mycobacterium tuberculosis antigen 85B recognized by antigen-specific human CD4(+) T-cell lines. Mustafa, A.S., Shaban, F.A., Abal, A.T., Al-Attiyah, R., Wiker, H.G., Lundin, K.E., Oftung, F., Huygen, K. Infect. Immun. (2000)
- Skin test with a timothy grass (Phleum pratense) pollen extract vs. IgE to a timothy extract vs. IgE to rPhl p 1, rPhl p 2, nPhl p 4, rPhl p 5, rPhl p 6, rPhl p 7, rPhl p 11, and rPhl p 12: epidemiological and diagnostic data. Mari, A. Clin. Exp. Allergy (2003)
- The alpha-type 85-kDa subunit of phosphatidylinositol 3-kinase is phosphorylated at tyrosines 368, 580, and 607 by the insulin receptor. Hayashi, H., Nishioka, Y., Kamohara, S., Kanai, F., Ishii, K., Fukui, Y., Shibasaki, F., Takenawa, T., Kido, H., Katsunuma, N. J. Biol. Chem. (1993)
- The isolation and characterization of a novel collagenolytic serine protease allergen (Der p 9) from the dust mite Dermatophagoides pteronyssinus. King, C., Simpson, R.J., Moritz, R.L., Reed, G.E., Thompson, P.J., Stewart, G.A. J. Allergy Clin. Immunol. (1996)
- Conformation- and fusion-defective mutations in the hypothetical phospholipid-binding and fusion peptides of viral hemorrhagic septicemia salmonid rhabdovirus protein G. Rocha, A., Ruiz, S., Tafalla, C., Coll, J.M. J. Virol. (2004)
- Effects of anti-PM-Scl 100 (Rrp6p exonuclease) antibodies on prenucleolar body dynamics at the end of mitosis. Fomproix, N., Hernandez-Verdun, D. Exp. Cell Res. (1999)
- The significance of some immunoserologic diagnostic tests in systemic diseases. Rozman, B., Kveder, T., Lestan, B. Acta Med. Austriaca (1988)
- Immunoserological aspects of idiopathic inflammatory muscle disease. Rozman, B., Bozic, B., Kos-Golja, M., Plesivcnik-Novljan, M., Kveder, T. Wien. Klin. Wochenschr. (2000)
- PM-Scl-75 is the main autoantigen in patients with the polymyositis/scleroderma overlap syndrome. Raijmakers, R., Renz, M., Wiemann, C., Egberts, W.V., Seelig, H.P., van Venrooij, W.J., Pruijn, G.J. Arthritis Rheum. (2004)
- Evaluation of recombinant and native timothy pollen (rPhl p 1, 2, 5, 6, 7, 11, 12 and nPhl p 4)- specific IgG4 antibodies induced by subcutaneous immunotherapy with timothy pollen extract in allergic patients. Rossi, R.E., Monasterolo, G. Int. Arch. Allergy Immunol. (2004)
- Allergens of wild house dust mites: environmental Der p 1 and Der p 2 sequence polymorphisms. Smith, W.A., Hales, B.J., Jarnicki, A.G., Thomas, W.R. J. Allergy Clin. Immunol. (2001)