Gene Review:
A4GALT - alpha 1,4-galactosyltransferase
Homo sapiens
Synonyms:
A14GALT, A4GALT1, Alpha-1,4-N-acetylglucosaminyltransferase, Alpha-1,4-galactosyltransferase, Alpha4Gal-T1, ...
- Genetic influence on the structural variations of the abnormal prion protein. Parchi, P., Zou, W., Wang, W., Brown, P., Capellari, S., Ghetti, B., Kopp, N., Schulz-Schaeffer, W.J., Kretzschmar, H.A., Head, M.W., Ironside, J.W., Gambetti, P., Chen, S.G. Proc. Natl. Acad. Sci. U.S.A. (2000)
- Multiple forms of protein kinase from normal human brain and glioblastoma. Frattola, L., Canal, N., Ferrarese, C., Tonini, C., Tonon, G., Villani, R., Trabucchi, M. Cancer Res. (1983)
- Assembly of Theiler's virus recombinants used in mapping determinants of neurovirulence. Pritchard, A.E., Jensen, K., Lipton, H.L. J. Virol. (1993)
- Immunogenicity of synthetic peptides of Haemophilus influenzae type b outer membrane protein P1. Chong, P., Yang, Y.P., Persaud, D., Haer, M., Tripet, B., Tam, E., Sia, C., Klein, M. Infect. Immun. (1995)
- Detection of scrapie-associated fibril (SAF) proteins using anti-SAF antibody in non-purified tissue preparations. Rubenstein, R., Kascsak, R.J., Merz, P.A., Papini, M.C., Carp, R.I., Robakis, N.K., Wisniewski, H.M. J. Gen. Virol. (1986)
- Chronic wasting disease of elk and deer and Creutzfeldt-Jakob disease: comparative analysis of the scrapie prion protein. Xie, Z., O'Rourke, K.I., Dong, Z., Jenny, A.L., Langenberg, J.A., Belay, E.D., Schonberger, L.B., Petersen, R.B., Zou, W., Kong, Q., Gambetti, P., Chen, S.G. J. Biol. Chem. (2006)
- Insulin stimulates the kinase activity of RAC-PK, a pleckstrin homology domain containing ser/thr kinase. Kohn, A.D., Kovacina, K.S., Roth, R.A. EMBO J. (1995)
- Isolation of multipotent progenitor cells from human fetal liver capable of differentiating into liver and mesenchymal lineages. Dan, Y.Y., Riehle, K.J., Lazaro, C., Teoh, N., Haque, J., Campbell, J.S., Fausto, N. Proc. Natl. Acad. Sci. U.S.A. (2006)
- Protein turnover as a component in the light/dark regulation of phosphoenolpyruvate carboxylase protein-serine kinase activity in C4 plants. Jiao, J., Echevarría, C., Vidal, J., Chollet, R. Proc. Natl. Acad. Sci. U.S.A. (1991)
- Furin gene (fur) regulation in differentiating human megakaryoblastic Dami cells: involvement of the proximal GATA recognition motif in the P1 promoter and impact on the maturation of furin substrates. Laprise, M.H., Grondin, F., Cayer, P., McDonald, P.P., Dubois, C.M. Blood (2002)
- Functional interactions of phosphatidylinositol 3-kinase with GTPase-activating protein in 3T3-L1 adipocytes. DePaolo, D., Reusch, J.E., Carel, K., Bhuripanyo, P., Leitner, J.W., Draznin, B. Mol. Cell. Biol. (1996)
- Insomnia associated with thalamic involvement in E200K Creutzfeldt-Jakob disease. Taratuto, A.L., Piccardo, P., Reich, E.G., Chen, S.G., Sevlever, G., Schultz, M., Luzzi, A.A., Rugiero, M., Abecasis, G., Endelman, M., Garcia, A.M., Capellari, S., Xie, Z., Lugaresi, E., Gambetti, P., Dlouhy, S.R., Ghetti, B. Neurology (2002)
- Co-existence of hereditary spherocytosis and a new red cell pyruvate kinase variant: PK mallorca. Zarza, R., Moscardó, M., Alvarez, R., García, J., Morey, M., Pujades, A., Vives-Corrons, J.L. Haematologica (2000)
- Differential oncogene amplification in tumor cells from a patient treated with cisplatin and 5-fluorouracil. Kashani-Sabet, M., Lu, Y., Leong, L., Haedicke, K., Scanlon, K.J. Eur. J. Cancer (1990)
- Influence of guanidine on proteinase K resistance in vitro and infectivity of scrapie prion protein PrP(Sc). Gao, J.M., Zhou, X.B., Xiao, X.L., Zhang, J., Chen, L., Gao, C., Zhang, B.Y., Dong, X.P. Acta Virol. (2006)
- A single base insertion of the 4-alpha-galactosyltransferase gene led to the deficiency of Gb3 biosynthesis. Tanaka, M., Yamashita, N., Takahashi, J., Hirayama, F., Tani, Y., Shibata, H. Immunohematology / American Red Cross. (2006)
- Two previously proposed P1/P2-differentiating and nine novel polymorphisms at the A4GALT (Pk) locus do not correlate with the presence of the P1 blood group antigen. Hellberg, A., Chester, M.A., Olsson, M.L. BMC Genet. (2005)
- Cloning and expression of the histo-blood group Pk UDP-galactose: Ga1beta-4G1cbeta1-cer alpha1, 4-galactosyltransferase. Molecular genetic basis of the p phenotype. Steffensen, R., Carlier, K., Wiels, J., Levery, S.B., Stroud, M., Cedergren, B., Nilsson Sojka, B., Bennett, E.P., Jersild, C., Clausen, H. J. Biol. Chem. (2000)
- Molecular basis for the p phenotype. Identification of distinct and multiple mutations in the alpha 1,4-galactosyltransferase gene in Swedish and Japanese individuals. Furukawa, K., Iwamura, K., Uchikawa, M., Sojka, B.N., Wiels, J., Okajima, T., Urano, T., Furukawa, K. J. Biol. Chem. (2000)
- Human calcium-sensing receptor gene. Vitamin D response elements in promoters P1 and P2 confer transcriptional responsiveness to 1,25-dihydroxyvitamin D. Canaff, L., Hendy, G.N. J. Biol. Chem. (2002)
- The blood group P1 synthase gene is identical to the Gb3/CD77 synthase gene. A clue to the solution of the P1/P2/p puzzle. Iwamura, K., Furukawa, K., Uchikawa, M., Sojka, B.N., Kojima, Y., Wiels, J., Shiku, H., Urano, T., Furukawa, K. J. Biol. Chem. (2003)
- Expression of the Gb3/CD77 synthase gene in megakaryoblastic leukemia cells: implication in the sensitivity to verotoxins. Furukawa, K., Yokoyama, K., Sato, T., Wiels, J., Hirayama, Y., Ohta, M., Furukawa, K. J. Biol. Chem. (2002)
- Myotonic dystrophy kinase is a component of neuromuscular junctions. van der Ven, P.F., Jansen, G., van Kuppevelt, T.H., Perryman, M.B., Lupa, M., Dunne, P.W., ter Laak, H.J., Jap, P.H., Veerkamp, J.H., Epstein, H.F. Hum. Mol. Genet. (1993)
- Isolation and characterization of cytotoxic granules from human lymphokine (interleukin 2) activated killer cells. Lowrey, D.M., Hameed, A., Lichtenheld, M., Podack, E.R. Cancer Res. (1988)
- Characterization of a deaminated neuraminic acid-containing glycoprotein from the skin mucus of the loach, Misgurnus anguillicaudatus. Kimura, M., Hama, Y., Sumi, T., Asakawa, M., Rao, B.N., Horne, A.P., Li, S.C., Li, Y.T., Nakagawa, H. J. Biol. Chem. (1994)
- The reactions of antibodies to paragloboside (lacto-N-neotetraosyl ceramide) with human erythrocytes and lymphocytes. Schwarting, G.A., Marcus, D.M. J. Immunol. (1977)
- Curcumin decreases binding of Shiga-like toxin-1B on human intestinal epithelial cell line HT29 stimulated with TNF-alpha and IL-1beta: suppression of p38, JNK and NF-kappaB p65 as potential targets. Moon, D.O., Jin, C.Y., Lee, J.D., Choi, Y.H., Ahn, S.C., Lee, C.M., Jeong, S.C., Park, Y.M., Kim, G.Y. Biol. Pharm. Bull. (2006)
- Molecular basis for high renal cell sensitivity to the cytotoxic effects of shigatoxin-1: upregulation of globotriaosylceramide expression. Hughes, A.K., Ergonul, Z., Stricklett, P.K., Kohan, D.E., Ergonal, Z. J. Am. Soc. Nephrol. (2002)
- Molecular cloning of globotriaosylceramide/CD77 synthase, a glycosyltransferase that initiates the synthesis of globo series glycosphingolipids. Kojima, Y., Fukumoto, S., Furukawa, K., Okajima, T., Wiels, J., Yokoyama, K., Suzuki, Y., Urano, T., Ohta, M., Furukawa, K. J. Biol. Chem. (2000)
- Life-threatening nonspherocytic hemolytic anemia in a patient with a null mutation in the PKLR gene and no compensatory PKM gene expression. Diez, A., Gilsanz, F., Martinez, J., Pérez-Benavente, S., Meza, N.W., Bautista, J.M. Blood (2005)